Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Annette Höglund"'
Autor:
Jan Mitschke, Ralf Reski, Stefan A. Rensing, Oliver Kohlbacher, Janina Fuss, Torsten Blum, Annette Höglund
Publikováno v:
New Phytologist. 183:224-236
Summary • Dual targeting of proteins to more than one subcellular localization has been found in animals, in fungi and in plants. In the latter, ambiguous N-terminal targeting signals have been described that result in the protein being located in
Publikováno v:
Bioinformatics. 22:1158-1165
Motivation: Functional annotation of unknown proteins is a major goal in proteomics. A key annotation is the prediction of a protein's subcellular localization. Numerous prediction techniques have been developed, typically focusing on a single underl
Autor:
Annette Höglund, Pierre Dönnes
Publikováno v:
Genomics, Proteomics & Bioinformatics
Functional characterization of every single protein is a major challenge of the post-genomic era. The large-scale analysis of a cell’s proteins, proteomics, seeks to provide these proteins with reliable annotations regarding their interaction partn
Publikováno v:
Bioinformatics (Oxford, England). 23(11)
Motivation: Knowing the localization of a protein within the cell helps elucidate its role in biological processes, its function and its potential as a drug target. Thus, subcellular localization prediction is an active research area. Numerous locali
Autor:
Pierre Dönnes, John San Miguel, Hagit Shatkay, Torsten Blum, Scott Brady, Oliver Kohlbacher, Annette Höglund, Matthew Rocheford
Publikováno v:
Pacific Symposium on Biocomputing
Computational prediction of protein subcellular localization is a challenging problem. Several approaches have been presented during the past few years; some attempt to cover a wide variety of localizations, while others focus on a small number of lo
Autor:
Oliver Kohlbacher, Hans-Peter Lenhof, Nicole Comtesse, Pierre Dönnes, Annette Höglund, Marc Sturm, Christina Backes, Eckart Meese
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 18(12)
The development of human cancer is a highly complex process and can be considered the result of several combined events, such as genetic alterations, disturbance of signal transduction, or failure of immunological surveillance. Cancer-related databas
Publikováno v:
Functionalintegrative genomics. 3(3)
Dramatic progress in deciphering the regulatory controls in Saccharomyces cerevisiae has been enabled by the fusion of high-throughput genomics technologies with advanced sequence analysis algorithms. Sets of genes likely to function together and wit
Autor:
Annette Höglund, Oliver Kohlbacher
Publikováno v:
Proteome Science. 2:3
Gene regulation in higher organisms is achieved by a complex network of transcription factors (TFs). Modulating gene expression and exploring gene function are major aims in molecular biology. Furthermore, the identification of putative target genes
Publikováno v:
Bioinformatics; May2006, Vol. 22 Issue 10, p1158-1165, 8p