Zobrazeno 1 - 10
of 564
pro vyhledávání: '"Annette G Beck-Sickinger"'
Autor:
Xuan Zhang, Tina Weiß, Mary Hongying Cheng, Siqi Chen, Carla Katharina Ambrosius, Anne Sophie Czerniak, Kunpeng Li, Mingye Feng, Ivet Bahar, Annette G Beck-Sickinger, Cheng Zhang
Publikováno v:
PLoS Biology, Vol 21, Iss 12, p e3002188 (2023)
Chemokine-like receptor 1 (CMKLR1), also known as chemerin receptor 23 (ChemR23) or chemerin receptor 1, is a chemoattractant G protein-coupled receptor (GPCR) that responds to the adipokine chemerin and is highly expressed in innate immune cells, in
Externí odkaz:
https://doaj.org/article/3564aaff35224cb3be106e5a8988ac7e
Autor:
Gregory Sliwoski, Mario Schubert, Jan Stichel, David Weaver, Annette G Beck-Sickinger, Jens Meiler
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157146 (2016)
The human neuropeptide Y4 receptor (Y4R) and its native ligand, pancreatic polypeptide, are critically involved in the regulation of human metabolism by signaling satiety and regulating food intake, as well as increasing energy expenditure. Thus, thi
Externí odkaz:
https://doaj.org/article/5768531ec63840fbb1a6fec0b5b7d616
Autor:
Gerrit Vortmeier, Stephanie H DeLuca, Sylvia Els-Heindl, Constance Chollet, Holger A Scheidt, Annette G Beck-Sickinger, Jens Meiler, Daniel Huster
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122444 (2015)
The peptide hormone ghrelin activates the growth hormone secretagogue receptor 1a, also known as the ghrelin receptor. This 28-residue peptide is acylated at Ser3 and is the only peptide hormone in the human body that is lipid-modified by an octanoyl
Externí odkaz:
https://doaj.org/article/19d0b2b4c83e415fb09d733911cacbee
Publikováno v:
Frontiers in Endocrinology, Vol 4 (2013)
The neuropeptide Y system is a multireceptor/multiligand system consisting of four receptors in humans (hY1, hY2, hY4, hY5) and three agonists (NPY, PYY, PP) that activate these receptors with different potency. The relevance of this system in diseas
Externí odkaz:
https://doaj.org/article/e2bb3c36ef12455fb8539e9e9651bb21
Autor:
Robert Spinnler, Theresa Gorski, Katharina Stolz, Susanne Schuster, Antje Garten, Annette G Beck-Sickinger, Marten A Engelse, Eelco J P de Koning, Antje Körner, Wieland Kiess, Kathrin Maedler
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54106 (2013)
AIMS/HYPOTHESIS:Obesity is associated with a dysregulation of beta-cell and adipocyte function. The molecular interactions between adipose tissue and beta-cells are not yet fully elucidated. We investigated, whether or not the adipocytokine Nicotinam
Externí odkaz:
https://doaj.org/article/16ecf63bb88d40f49fadc4034a13247d
Autor:
Iulian Pana, Anca Constantina Parau, Cosmin Mihai Cotrut, Mihaela Dinu, Diana Maria Vranceanu, Adrian E. Kiss, Giuseppe Serratore, Dennis A. Böhner, Catalin Vitelaru, Giuseppina Ambrogio, Annette G. Beck-Sickinger, Alina Vladescu (Dragomir)
Publikováno v:
Ceramics International. 49:22340-22354
Publikováno v:
ChemBioChem.
Autor:
Thomas Westfall, Thue Schwartz, Remi Quirion, Martin C. Michel, Dan Larhammar, Herbert Herzog, Henri N. Doods, Helen M. Cox, William F. Colmers, Annette G. Beck-Sickinger
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Neuropeptide Y (NPY) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Neuropeptide Y Receptors [158]) are activated by the endogenous peptides neuropeptide Y, neuropeptide Y-(3-36), peptide YY, PYY-(3-36) and pancreatic polypeptide
Publikováno v:
Biological Chemistry. 403:625-642
Chemerin is a small chemotactic protein and a key player in initiating the early immune response. As an adipokine, chemerin is also involved in energy homeostasis and the regulation of reproductive functions. Secreted as inactive prochemerin, it reli
Autor:
Oanh Vu, Brian Joseph Bender, Lisa Pankewitz, Daniel Huster, Annette G. Beck-Sickinger, Jens Meiler
Publikováno v:
Molecules, Vol 27, Iss 210, p 210 (2022)
Molecules
Molecules
G protein-coupled receptors (GPCRs) represent the largest membrane protein family and a significant target class for therapeutics. Receptors from GPCRs’ largest class, class A, influence virtually every aspect of human physiology. About 45% of the