Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Annette Fink"'
Autor:
Julia K. Büttner, Sara Becker, Annette Fink, Melanie M. Brinkmann, Rafaela Holtappels, Matthias J. Reddehase, Niels A. Lemmermann
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
CD8 T cells are important antiviral effectors in the adaptive immune response to cytomegaloviruses (CMV). Naïve CD8 T cells can be primed by professional antigen-presenting cells (pAPCs) alternatively by “direct antigen presentation” or “antig
Externí odkaz:
https://doaj.org/article/79934bb9fe914af98a35679105d46474
Autor:
Louise Benning, Christian Morath, Annette Fink, Markus Rudek, Claudius Speer, Florian Kälble, Christian Nusshag, Jörg Beimler, Constantin Schwab, Rüdiger Waldherr, Martin Zeier, Caner Süsal, Thuong Hien Tran
Publikováno v:
Transplant International, Vol 36 (2023)
Donor-derived cell-free DNA (dd-cfDNA) identifies allograft injury and discriminates active rejection from no rejection. In this prospective study, 106 kidney transplant recipients with 108 clinically indicated biopsies were enrolled at Heidelberg Un
Externí odkaz:
https://doaj.org/article/dd27de4fe00d46a19c12bf2a47c50f5f
Autor:
Sara Becker, Annette Fink, Jürgen Podlech, Irina Giese, Julia K. Schmiedeke, Thomas Bukur, Matthias J. Reddehase, Niels A. Lemmermann
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Murine cytomegalovirus (mCMV) codes for MHC class-I trafficking modulators m04/gp34, m06/gp48, and m152/gp40. By interacting with the MHC class-Iα chain, these proteins disconnect peptide-loaded MHC class-I (pMHC-I) complexes from the constitutive v
Externí odkaz:
https://doaj.org/article/c237d69e45f24517b9089c80522eb416
Publikováno v:
Viruses, Vol 14, Iss 1, p 128 (2022)
Cytomegaloviruses (CMVs) are host species-specific and have adapted to their respective mammalian hosts during co-evolution. Host-adaptation is reflected by “private genes” that have specialized in mediating virus-host interplay and have no seque
Externí odkaz:
https://doaj.org/article/cc07751c5dc74a3d91106a6a0f0b0516
Autor:
Annette Fink, Julia K. Büttner, Doris Thomas, Rafaela Holtappels, Matthias J. Reddehase, Niels A. W. Lemmermann
Publikováno v:
Viruses, Vol 6, Iss 2, Pp 808-831 (2014)
Viral CD8 T-cell epitopes, represented by viral peptides bound to major histocompatibility complex class-I (MHC-I) glycoproteins, are often identified by “reverse immunology”, a strategy not requiring biochemical and structural knowledge of the a
Externí odkaz:
https://doaj.org/article/e8afdfcd268a44c88fd6c3a3a2f01459
Publikováno v:
Viruses, Vol 5, Iss 12, Pp 3171-3191 (2013)
The MHC-class I (MHC-I)-like viral (MHC-Iv) m152 gene product of murine cytomegalovirus (mCMV) was the first immune evasion molecule described for a member of the β-subfamily of herpesviruses as a paradigm for analogous functions of human cytomegalo
Externí odkaz:
https://doaj.org/article/e1852653903b47138e3ee6c3efc579db
Autor:
Martin Zeier, Sabine Scherer, Thuong Hien Tran, Andrea Ruhenstroth, Caner Süsal, Arianeb Mehrabi, Chen Tang, Annette Fink, Christian Morath, Sofia Cinca, Christian Unterrainer
Publikováno v:
HLA. 98:423-430
HLA matching and avoidance of unacceptable mismatches are important aspects in the selection of donors for solid organ transplantation. The impact of HLA-DPB1 incompatibility on the outcomes of kidney transplantation is not fully understood. We inves
Autor:
Luise Florin, Annette Fink, Franziska Blaum, Matthias J. Reddehase, Niels A. W. Lemmermann, Snježana Mikuličić
Publikováno v:
Medical Microbiology and Immunology. 208:531-542
As an immune evasion mechanism, cytomegaloviruses (CMVs) have evolved proteins that interfere with cell surface trafficking of MHC class-I (MHC-I) molecules to tone down recognition by antiviral CD8 T cells. This interference can affect the trafficki
Autor:
Annette Fink, Dianne De Santis, Manuela Testi, Marcel G.J. Tilanus, Blanka Vidan-Jeras, Thuong Hien Tran, Gottfried Fischer, Mathijs Groeneweg, Ingrid Fae, Marco Andreani, Ben M. Matern, Christina E.M. Voorter, R. Whidborne, Sendi Montanic
Publikováno v:
Human Immunology. 79(11):763-772
The gold standard for typing at the allele level of the highly polymorphic Human Leucocyte Antigen (HLA) gene system is sequence based typing. Since sequencing strategies have mainly focused on identification of the peptide binding groove, full-lengt
Autor:
Rafaela Holtappels, Dorothea Gillert-Marien, Annette Fink, Kirsten Freitag, Stefan Ebert, Kerstin M. Gergely, Jürgen Podlech, Julia K. Büttner, Matthias J. Reddehase, Doris Thomas
Publikováno v:
Medical Microbiology and Immunology. 201:527-539
Reactivation of latent cytomegalovirus (CMV) in the transient state of immunodeficiency after hematopoietic cell transplantation (HCT) is the most frequent and severe viral complication endangering leukemia therapy success. By infecting the bone marr