Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Annette Draeger"'
Autor:
Hervé Besançon, Viktoriia Babiychuk, Yu Larpin, René Köffel, Dominik Schittny, Lara Brockhus, Lucy J. Hathaway, Parham Sendi, Annette Draeger, Eduard Babiychuk
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Streptococcal infections are associated with life-threatening pneumonia and sepsis. The rise in antibiotic resistance calls for novel approaches to treat bacterial diseases. Anti-virulence strategies promote a natural way of patho
Externí odkaz:
https://doaj.org/article/ef137a52471f4d6bbf852b1b4d4f936b
Autor:
Heidi Wolfmeier, Samuel J. T. Wardell, Leo T. Liu, Reza Falsafi, Annette Draeger, Eduard B. Babiychuk, Daniel Pletzer, Robert E. W. Hancock
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aur
Externí odkaz:
https://doaj.org/article/840210bfc16444c586864df92061739c
Autor:
Heidi Wolfmeier, Sarah C. Mansour, Leo T. Liu, Daniel Pletzer, Annette Draeger, Eduard B. Babiychuk, Robert E.W. Hancock
Publikováno v:
EBioMedicine, Vol 33, Iss , Pp 211-217 (2018)
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), typified by the pulse-field type USA300, is an emerging endemic pathogen that is spreading rapidly among healthy people. CA-MRSA causes skin and soft tissue infections, life-
Externí odkaz:
https://doaj.org/article/015e710ff6b84a8094608431c5de5ae3
Autor:
René Köffel, Heidi Wolfmeier, Yu Larpin, Hervé Besançon, Roman Schoenauer, Viktoria S. Babiychuk, Patrick Drücker, Thomas Pabst, Timothy J. Mitchell, Eduard B. Babiychuk, Annette Draeger
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Bacterial infectious diseases are a leading cause of death. Pore-forming toxins (PFTs) are important virulence factors of Gram-positive pathogens, which disrupt the plasma membrane of host cells and can lead to cell death. Yet, host defense and cell
Externí odkaz:
https://doaj.org/article/ab204a27906c4eb7b16198098641d220
Autor:
Charlene Börtlein, Annette Draeger, Roman Schoenauer, Alexander Kuhlemann, Markus Sauer, Sibylle Schneider-Schaulies, Elita Avota
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
By promoting ceramide release at the cytosolic membrane leaflet, the neutral sphingomyelinase 2 (NSM) is capable of organizing receptor and signalosome segregation. Its role in T cell receptor (TCR) signaling remained so far unknown. We now show that
Externí odkaz:
https://doaj.org/article/6c049a1c658e433bbd1cfdc2bd0d7a32
Autor:
Alexander P Atanassoff, Heidi Wolfmeier, Roman Schoenauer, Andrea Hostettler, Avi Ring, Annette Draeger, Eduard B Babiychuk
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89743 (2014)
Pathogenic bacteria secrete pore-forming toxins that permeabilize the plasma membrane of host cells. Nucleated cells possess protective mechanisms that repair toxin-damaged plasmalemma. Currently two putative repair scenarios are debated: either the
Externí odkaz:
https://doaj.org/article/8beed59bec4244f78bc9e0a34ea23a3c
Autor:
Eduard B Babiychuk, Alexander P Atanassoff, Katia Monastyrskaya, Christina Brandenberger, Daniel Studer, Catherine Allemann, Annette Draeger
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23706 (2011)
Ceramide is a key lipid mediator of cellular processes such as differentiation, proliferation, growth arrest and apoptosis. During apoptosis, ceramide is produced within the plasma membrane. Although recent data suggest that the generation of intrace
Externí odkaz:
https://doaj.org/article/40a691cd877a49669246d82f976f1014
Autor:
Audrey Jalabert, Audrey Villard-Garon, Sophie Rome, Annette Draeger, Pascal Colosetti, Christophe O. Soulage, Françoise Hullin-Matsuda, Isabelle Delton, Cyrille Bergerot, Céline Luquain-Costaz, Elisabeth Errazuriz-Cerda, Valentin Leuzy, Mathilde Di Filippo, Annie Durand, Baptiste Fourmaux, Maxence Rabia, René Köffel, Philippe Moulin
Publikováno v:
Biochimie
Biochimie, 2020, ⟨10.1016/j.biochi.2020.07.005⟩
Biochimie, 2020, ⟨10.1016/j.biochi.2020.07.005⟩
International audience; Bis(monoacylglycero)phosphate (BMP), also known as lysobisphosphatidic acid (LBPA), is a phospholipid specifically enriched in the late endosome-lysosome compartment playing a crucial role for the fate of endocytosed component
Autor:
Heidi, Wolfmeier, Samuel J T, Wardell, Leo T, Liu, Reza, Falsafi, Annette, Draeger, Eduard B, Babiychuk, Daniel, Pletzer, Robert E W, Hancock
Publikováno v:
Frontiers in microbiology. 13
Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as
Autor:
Eduard B. Babiychuk, Yu Larpin, Annette Draeger, Mircea-Ioan Iacovache, Victoriia S. Babiychuk, Hervé Besançon, Benoît Zuber, René Köffel
Publikováno v:
The FASEB Journal. 34:1665-1678
Bacterial infectious diseases can lead to death or to serious illnesses. These outcomes are partly the consequence of pore‐forming toxins, which are secreted by the pathogenic bacteria (eg, pneumolysin of Streptococcus pneumoniae). Pneumolysin bind