Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Annette C. Crowley"'
Autor:
David E. Merriam, Janice S. Miller, Joseph D. Buxbaum, Wilma Wasco, Christina Lilliehook, Eun-Kyoung Choi, Nikhat F. Zaidi, Annette C. Crowley
Publikováno v:
Journal of Biological Chemistry. 276:19197-19204
Calsenilin is a member of the recoverin family of neuronal calcium-binding proteins that we have previously shown to interact with presenilin 1 (PS1) and presenilin 2 (PS2) holoproteins. The expression of calsenilin can regulate the levels of a prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb37e995ac08a8b70222e2e947087f19
https://doi.org/10.1074/jbc.m008597200
https://doi.org/10.1074/jbc.m008597200
Autor:
Rudolph E. Tanzi, P. D. Jondro, Ephrat Levy-Lahad, Annette C. Crowley, Junko Oshima, Ellen Nemens, Ying-Hui Fu, Parvoneh Poorkaj, Warren H. Pettingell, Suzanne Y. Guénette, Kai Wang, Stephen D. Schmidt, Chang En Yu, Wilma Wasco, Thomas D. Bird, Gerard D. Schellenberg, Donna M. Romano, Ellen M. Wijsman, David J. Galas
Publikováno v:
Science. 269:973-977
A candidate gene for the chromosome 1 Alzheimer's disease (AD) locus was identified (STM2). The predicted amino acid sequence for STM2 is homologous to that of the recently cloned chromosome 14 AD gene (S182). A point mutation in STM2, resulting in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::303621a1f48a9edf64e5ecad3af39728
https://doi.org/10.1126/science.7638622
https://doi.org/10.1126/science.7638622
Autor:
David E. Merriam, Joseph D. Buxbaum, Dennis A. Ausiello, Weiming Xia, Janice S. Miller, Tina L. Tekirian, Annette C. Crowley, Helena Chan, Dennis Brown, Wilma Wasco, Vladimir Marshansky
Publikováno v:
Brain research. Molecular brain research. 96(1-2)
Mutations in the genes that encode the presenilin 1 and 2 (PS1 and PS2) proteins cause the majority of familial Alzheimer’s disease (FAD). Differential cleavage of the presenilins results in a generation of at least two C-terminal fragments (CTFs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd726ca2ca5af3092e8377dd0b459b01
https://pubmed.ncbi.nlm.nih.gov/11731004
https://pubmed.ncbi.nlm.nih.gov/11731004
Autor:
Annette C. Crowley, Joseph D. Buxbaum, Christina Lilliehook, Eun-Kyoung Choi, Wilma Wasco, Yuxia Luo, David E. Merriam
Publikováno v:
Nature medicine. 4(10)
Most early-onset familial Alzheimer disease (AD) cases are caused by mutations in the highly related genes presenilin 1 (PS1) and presenilin 2 (PS2). Presenilin mutations produce increases in beta-amyloid (Abeta) formation and apoptosis in many exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87cf8ba50569e53984cf88cd88224b2
https://pubmed.ncbi.nlm.nih.gov/9771743
https://pubmed.ncbi.nlm.nih.gov/9771743
Autor:
B. A. Kellerman, P. D. Jondro, Donna M. Romano, Robert D. Moir, Wilma Wasco, Rudolph E. Tanzi, David E. Merriam, Annette C. Crowley
Publikováno v:
Presenilins and Alzheimer’s Disease ISBN: 9783642721052
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of the central nervous system which is invariably associated with and defined by the presence of intracellular neurofibrillary tangles (NFT) and extracellular deposits of amyloid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83a9334ec122d6f16cd2882832606dd9
https://doi.org/10.1007/978-3-642-72103-8_7
https://doi.org/10.1007/978-3-642-72103-8_7
Autor:
Annette C. Crowley, Marc d. Paradis, Donna M. Romano, Dora M. Kovacs, P. St. George-Hyslop, Rudolph E. Tanzi, Warren H. Pettingell, Sandra M. Gaston, Sarada Gurubhagavatula, Jeffrey Peppercorn, Ashley I. Bush, Wilma Wasco, Haines Jl
Publikováno v:
Amyloid Protein Precursor in Development, Aging and Alzheimer’s Disease ISBN: 9783662011379
Alzheimer’s diseases (AD) is a major health problem which will continue to intensify in magnitude as the elderly in the population continue to increase in number. The age at which AD strikes is variable, ranging from the fourth to tenth decades, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f33974c9b00ed26114d789b21d98bedf
https://doi.org/10.1007/978-3-662-01135-5_17
https://doi.org/10.1007/978-3-662-01135-5_17
Autor:
Christina Lilliehook, Janice S. Miller, Wilma Wasco, Nikhat F. Zaidi, Annette C. Crowley, David M. Merriam, Joseph D. Buxbaum, Eun-Kyoung Choi
Publikováno v:
Neurobiology of Aging. 21:117
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::321a35bc8157a131e54d5d82f5f6f523
https://doi.org/10.1016/s0197-4580(00)82328-3
https://doi.org/10.1016/s0197-4580(00)82328-3
Autor:
Joseph D. Buxbaum, David E. Merriam, Janice S. Miller, Weiming Xia, Annette C. Crowley, Tina L. Tekirian, Wilma Wasco
Publikováno v:
Neurobiology of Aging. 21:159
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::729587dcbf3e2f9a6a30fd0362c0af22
https://doi.org/10.1016/s0197-4580(00)82056-4
https://doi.org/10.1016/s0197-4580(00)82056-4