Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Annette Beyer-Mears"'
Publikováno v:
Diabetes. 42(12)
myo-Inositol depletion as a result of hyperglycemia is considered one of the leading contributors to chronic diabetic complications. We investigated the possible mechanisms through which elevated extracellular glucose levels affect the loss of intrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db67ea3a5a9c96b480ff42aa4987b77f
https://pubmed.ncbi.nlm.nih.gov/8243820
https://pubmed.ncbi.nlm.nih.gov/8243820
Autor:
Annette Beyer-Mears, Frederick T. Murray, Charles A. Sninsky, Richard D. Johnson, Anders A. F. Sima, Don F. Cameron, Helena P. Selawry
Publikováno v:
Transplantation. 56(3)
Only limited studies are available that assess diabetic complications following islet cell transplantation. Our objectives were to quantitate urine total protein, sural nerve morphometry, and sexual function in the diabetic BB/WOR male rat following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952a9c57f0ae937f016f06a9efa0d642
https://pubmed.ncbi.nlm.nih.gov/8212166
https://pubmed.ncbi.nlm.nih.gov/8212166
Publikováno v:
Experimental Eye Research. 27:627-635
Reversal of the galactose cataract in neonatal rat lenses involves a decrease in lenticular galactitol, a recovery of existing fiber contour and interdigitation, and a production of new fibers. The onset of neonatal cataractogenesis appeared at 7 day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54897ac4f4cecca4db27cd2d73b19149
https://doi.org/10.1016/0014-4835(78)90030-1
https://doi.org/10.1016/0014-4835(78)90030-1
Publikováno v:
Diabetes. 33:604-607
Although enhanced activity of the polyol pathway has been implicated in the pathogenesis of certain complications of diabetes, evidence that aldose reductase activity and sorbitol content are increased in the characteristic tissue site of the diabeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ff08e5cb7aae58f532a2f30ad5aa9a
https://doi.org/10.2337/diabetes.33.6.604
https://doi.org/10.2337/diabetes.33.6.604
Publikováno v:
Experimental eye research. 28(6)
Aldose reductase has been implicated in the pathogenesis of sugar cataracts, therefore inhibition of this enzyme may represent a pharmacological approach for the delay and possible prevention of cataractogenesis induced by diabetes or glactosemia. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265bf1a6ecf0f8413b69164a2fc4bf7c
https://pubmed.ncbi.nlm.nih.gov/111955
https://pubmed.ncbi.nlm.nih.gov/111955
Autor:
Annette Beyer-Mears
Publikováno v:
Metabolism: clinical and experimental. 35(4 Suppl 1)
Nephropathy is a serious complication of Type I or insulin-dependent diabetes mellitus (IDDM) with a poor prognosis after the onset of proteinuria. Since aldose reductase may be implicated in the pathogenesis of proteinuria, onset and reversal studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2595b10bc19c47788b9223c6e1d836
https://pubmed.ncbi.nlm.nih.gov/3083209
https://pubmed.ncbi.nlm.nih.gov/3083209
Publikováno v:
Experimental eye research. 27(3)
Cortical fiber development in the neonatal rat lens was affected in offspring nursed for their first 20 days by mother rats placed on a 50% galactose diet. Scanning electron micrographs from five regions of the cataractous lenses were compared with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d70d9f5852c0900561ee25457315644
https://pubmed.ncbi.nlm.nih.gov/710540
https://pubmed.ncbi.nlm.nih.gov/710540