Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Annette Bak"'
Autor:
Joseph W. Polli, Christopher R. McCurdy, Dale Eric Wurster, Binodh S. DeSilva, Annette Bak, Reina Bendayan, Bernd Meibohm, Allen C. Templeton, William Weiser, for the AAPS Leadership
Publikováno v:
AAPS Open, Vol 4, Iss 1, Pp 1-4 (2018)
Externí odkaz:
https://doaj.org/article/333fd29abf4e46938308e09081a6149f
Autor:
Annette Bak
Publikováno v:
Molecular Pharmaceutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86ea28d4ea106e6f49b8cb7abe011fee
https://doi.org/10.1021/acs.molpharmaceut.3c00389
https://doi.org/10.1021/acs.molpharmaceut.3c00389
Autor:
Richard L. Kendall, Robert Radinsky, Stephanie Geuns-Meyer, Vinod F. Patel, Isabelle Dussault, Mary Stanton, Annette Bak, Laurie B. Schenkel, Karina Romero, Philip R. Olivieri, Hanh Nho Nguyen, Brian L. Hodous, Holly L. Deak, Victor J. Cee, Sandra Ross, Patricia McElroy, Patrick Eden, Beth Ziegler, Grace Chung, Tammy L. Bush, Marc Payton
Supplementary Methods, Figures 1-5 from Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7147a5f5dbda291c8291002c611e48dd
https://doi.org/10.1158/0008-5472.22387907.v1
https://doi.org/10.1158/0008-5472.22387907.v1
Autor:
Prasath Paramasivam, Christian Franke, Martin Stöter, Andreas Höijer, Stefano Bartesaghi, Alan Sabirsh, Lennart Lindfors, Marianna Yanez Arteta, Anders Dahlén, Annette Bak, Shalini Andersson, Yannis Kalaidzidis, Marc Bickle, Marino Zerial
Publikováno v:
Journal of cell biology, The
The Journal of Cell Biology
The Journal of Cell Biology
Paramasivam et al. compared the endosomal trafficking of six LNP-mRNA formulations. LNP-mRNA accumulates in large endosomes impaired in acidification and unproductive for delivery. Super-resolution microscopy allowed visualization of single LNP-mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc61a8121495d6754b1d0cac82e07022
https://hdl.handle.net/21.11116/0000-000B-0339-2
https://hdl.handle.net/21.11116/0000-000B-0339-2
Autor:
Meenakshi Arora, Annette Bak, Nigel M. Davies, Ahil N. Ganesh, Sudhakar Garad, Eric Gruff, Tariq Islam, Mark J. Jackman, Swapnil Khadke, Fiona MacDougall, Sanyogitta Puri, M.N.V. Ravi Kumar, Jefferson D. Revell, Manuel V. Sanchez-Felix, J. Anand Subramony, Ruchit Trivedi, Puneet Tyagi, Dianxiong Zou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::984d7e77e384dfc40c26f3b082286337
https://doi.org/10.1016/b978-0-12-821061-1.00015-0
https://doi.org/10.1016/b978-0-12-821061-1.00015-0
Publikováno v:
Journal of Pharmaceutical Sciences. 108:3169-3175
Cell and gene therapies have the potential to be curative for severe disease states such as cancer or incurable orphan genetic diseases. Despite the promise, there are only few such therapies available, although more are appearing in pharmaceutical p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb957a83feb3684dd0bde4ab4830ba6
https://doi.org/10.1016/j.xphs.2019.05.027
https://doi.org/10.1016/j.xphs.2019.05.027
Autor:
Shalini Andersson, Stefano Bartesaghi, Prasath Paramasivam, Marc Bickle, Marino Zerial, Alan Sabirsh, Lennart Lindfors, Christian Franke, Annette Bak, Anders Dahlén, Andreas Höijer, Martin Stöter, Yannis Kalaidzidis, Marianna Yanez Arteta
Delivery of exogenous mRNA using lipid nanoparticles (LNP) is a promising strategy for therapeutics. However, a bottleneck remains the poor understanding of the parameters that correlate with endosomal escape vs. cytotoxicity. To address this problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::646ca03da0782f7c1f081d5dc217d96d
https://doi.org/10.1101/2020.12.18.423541
https://doi.org/10.1101/2020.12.18.423541
Autor:
Babak Alaei, Annette Bak, Sanlin Robinson, Maryam Clausen, Julie Williams, Pernille Laerkegaard Hansen, Graham Belfield, Ryan Hicks, Kimberly A. Homan, Lena William-Olsson, Jennifer A. Lewis
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims Questions abound regarding the translation of in vitro 2D cell culture systems to the human setting. This is especially true of the kidney in which there is a complex hierarchical structure and a multitude of cell types. While it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ce266b748e48af6068ec061a4d87de7
https://doi.org/10.1093/ndt/gfaa142.p0658
https://doi.org/10.1093/ndt/gfaa142.p0658
Publikováno v:
Expert opinion on drug delivery. 16(11)
Introduction: The delivery of nucleic acid therapeutics through non-viral carriers face multiple biological barriers that reduce their therapeutic efficiency. Despite great progress, there remains a significant technological gap that continues to lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81ec4e26b93af1e9c10001f38b2ffa6
https://pubmed.ncbi.nlm.nih.gov/31498013
https://pubmed.ncbi.nlm.nih.gov/31498013