Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Annette Bérault"'
Publikováno v:
Biochemical Pharmacology. 62:329-334
The GnRH-R belongs to the superfamily of heptahelical GPCRs. A three-dimensional model of GnRH binding to its receptor predicted that Trp3 was the most deeply buried residue, potentially allowing it to interact with both Trp279, a highly conserved re
Autor:
Yannick Lerrant, Raymond Counis, Claude Bouchaud, Ghislaine Garrel, Solange Magre, Annette Bérault, Céline Siriostis
Publikováno v:
Endocrinology. 139:2163-2170
To determine the site and mechanism of action of gonadal steroids on pituitary nitric oxide synthase type I (NOS I), present in both gonadotrophs and folliculo-stellate cells, the effects of castration and steroids were examined in male rats, in the
Autor:
Pulak R Manna, Josette Berreur-Bonnenfant, Richard Delahaye, Raymond Counis, Paul Berreur, Annette Bérault
Publikováno v:
Molecular and Cellular Endocrinology. 135:119-127
Increasing evidence exist that multiple G proteins mediate the effects of gonadotropin-releasing hormone (GnRH) on the synthesis and release of pituitary gonadotropins. In the present study, we have expressed the rat GnRH receptor (GnRH-R) in insect
Autor:
Nadine Noel, Edward H. Leiter, Muriel T. Davisson, Jolanta Polkowska, Annette Bérault, Marian Jutisz, David E. Harrison, Hendrick G. Bedigian, Wesley G. Beamer, Ilse Hurbain-Kosmath, Anne Bohin
Publikováno v:
In Vitro Cellular & Developmental Biology. 26:431-440
An epithelial cell line (RC-4B/C) was established from a pituitary adenoma obtained from a 3-yr-old (ACI/fMai X F344/fMai)F1 male rat. Before Year 5 in vitro, RC-4B/C cells could not be viably recovered from cryogenic storage. Recovery of viable cell
Publikováno v:
Molecular pharmacology. 57(3)
Previous studies have established that the interaction of gonadotropin-releasing hormone (GnRH) with its receptor (GnRHR) would require partial entry of the N- and C-terminal regions of ligand into the transmembrane core. The functional significance
Publikováno v:
The Journal of endocrinology. 162(3)
The demonstration of an inhibitory effect of gonadotropin-releasing hormone (GnRH) agonists upon steroidogenesis in hypophysectomized rats and the presence of mRNA coding for GnRH and GnRH receptors (GnRH-R) in rat gonads suggests that GnRH can act l
Publikováno v:
Neuroendocrinology. 54(3)
Using single hormone-staining immunocytochemical methods, we have recently characterized a novel cell line, RC-4B/C, established from an aged male rat pituitary adenoma. This cell line contained all known anterior pituitary cell types including gonad
Publikováno v:
Molecular and Cellular Endocrinology. 5:365-377
Specific binding studies of tritium-labeled LH-RH to sheep anterior pituitary membranes at 37 degrees C showed a maximum of binding capacity of 110 +/- 20 mol/mg protein with an association rate constant of 2 +/- 1 X 10(5) M-1 S-1 and a dissociation
Publikováno v:
Journal of Endocrinology. 98:391-399
We have investigated the effect of the time of culture on cell number, cell content of LH, cell responsiveness to gonadotrophin releasing hormone (GnRH) and binding parameters of GnRH in rat anterior pituitary cells in culture. Although a decrease in
ETUDE DE L'ACTION DU FACTEUR HYPOTHALAMIQUE LRF (LH-RELEASING FACTOR) CHEZ LE RAT IN VIVO & IN VITRO
Publikováno v:
Acta Endocrinologica. 55:481-496
A highly purified ovine LH-releasing factor (LRF) was obtained by a modification of the method previously described. After the fractionation of a crude hypothalamic extract on a Sephadex G-25 column, the LRF fraction was desalted and partially purifi