Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Annette, Palmer"'
Autor:
Yang Li, Klemens Horst, Johannes Greven, Ümit Mert, Ludmila Lupu, Annette Palmer, Lena Doerfer, Qun Zhao, Xing Zhang, Rebecca Halbgebauer, Anita Ignatius, Ingo Marzi, Martijn van Griensven, Elizabeth Balmayor, Frank Hildebrand, Tom Eirik Mollnes, Markus Huber-Lang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPolytrauma and hemorrhagic shock can lead to direct and indirect liver damage involving intricate pathophysiologic mechanisms. While hepatic function has been frequently highlighted, there is minimal research on how the receptor activator o
Externí odkaz:
https://doaj.org/article/0dd4a07f570e42239e70c8a2eeb84d2e
Autor:
Wolfgang P. Ruf, Annette Palmer, Lena Dörfer, Diana Wiesner, Eva Buck, Veselin Grozdanov, Jan Kassubek, Leda Dimou, Albert C. Ludolph, Markus Huber-Lang, Karin M. Danzer
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105877- (2022)
Background: Systemic and neuroinflammatory processes play key roles in neurodegenerative diseases such as Parkinson's disease (PD). Physical trauma which induces considerable systemic inflammatory responses, represents an evident environmental factor
Externí odkaz:
https://doaj.org/article/630a3504cc4f4361a4b215a42fb6b6a1
Autor:
Ludmila Lupu, Klemens Horst, Johannes Greven, Ümit Mert, Judith A.K. Ludviksen, Kristin Pettersen, Corinna Lau, Yang Li, Annette Palmer, Kang Qin, Xing Zhang, Benjamin Mayer, Martijn van Griensven, Markus Huber-Lang, Frank Hildebrand, Tom Eirik Mollnes
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Dysfunctional complement activation and Toll-like receptor signaling immediately after trauma are associated with development of trauma-induced coagulopathy and multiple organ dysfunction syndrome. We assessed the efficacy of the combined inhibition
Externí odkaz:
https://doaj.org/article/94889c1af8634422aecff717f0fb86a1
Autor:
Sandra A. Appiah, Christine L. Foxx, Dominik Langgartner, Annette Palmer, Cristian A. Zambrano, Sonja Braumüller, Evan J. Schaefer, Ulrich Wachter, Brooke L. Elam, Peter Radermacher, Christopher E. Stamper, Jared D. Heinze, Stephanie N. Salazar, Amalia K. Luthens, Andrea L. Arnold, Stefan O. Reber, Markus Huber-Lang, Christopher A. Lowry, Rebecca Halbgebauer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Severe injuries are frequently accompanied by hemorrhagic shock and harbor an increased risk for complications. Local or systemic inflammation after trauma/hemorrhage may lead to a leaky intestinal epithelial barrier and subsequent transloca
Externí odkaz:
https://doaj.org/article/725133c0dc8249f996d2bb34ef813eff
Autor:
Shinjini Chakraborty, Veronika Eva Winkelmann, Sonja Braumüller, Annette Palmer, Anke Schultze, Bettina Klohs, Anita Ignatius, Axel Vater, Michael Fauler, Manfred Frick, Markus Huber-Lang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Singular blockade of C5a in experimental models of sepsis is known to confer protection by rescuing lethality and decreasing pro-inflammatory responses. However, the role of inhibiting C5a has not been evaluated in the context of sterile sys
Externí odkaz:
https://doaj.org/article/f879c60c4cec486cafd3a5402fbf3955
Autor:
Tanja Seibold, Jonathan Schönfelder, Florian Weeber, André Lechel, Milena Armacki, Mareike Waldenmaier, Christoph Wille, Annette Palmer, Rebecca Halbgebauer, Ebru Karasu, Markus Huber‐Lang, Miriam Kalbitz, Peter Radermacher, Stephan Paschke, Thomas Seufferlein, Tim Eiseler
Publikováno v:
Advanced Science, Vol 8, Iss 24, Pp n/a-n/a (2021)
Abstract Trauma is the leading cause of death in individuals under 44 years of age. Thorax trauma (TxT) is strongly associated with trauma‐related death, an unbalanced innate immune response, sepsis, acute respiratory distress syndrome, and multipl
Externí odkaz:
https://doaj.org/article/7345cc7ca69d499483e24bd2b85da2a1
Autor:
Birte Weber, Ina Lackner, Melanie Haffner-Luntzer, Annette Palmer, Jochen Pressmar, Karin Scharffetter-Kochanek, Bernd Knöll, Hubert Schrezenemeier, Borna Relja, Miriam Kalbitz
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Trauma is the leading cause of mortality in humans below the age of 40. Patients injured by accidents frequently suffer severe multiple trauma, which is life-threatening and leads to death in many cases. In multiply injured patients, thoraci
Externí odkaz:
https://doaj.org/article/38fd9d61a33a4624918ded24a6c5e975
Autor:
Lisa Debler, Annette Palmer, Sonja Braumüller, Bettina Klohs, Tom Eirik Mollnes, Karlheinz Holzmann, Markus Huber-Lang, Rebecca Halbgebauer
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
The immune response following trauma represents a major driving force of organ dysfunction and poor outcome. Therefore, we investigated the influence of an additional hemorrhagic shock (HS) on the early posttraumatic immune dysbalance in the whole po
Externí odkaz:
https://doaj.org/article/76d38d44d7d2439db8adcd708ca57511
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Physical trauma can be considered an unrecognized “pandemic” because it can occur anywhere and affect anyone and represents a global burden. Following severe tissue trauma, patients frequently develop acute lung injury (ALI) and/or acute respirat
Externí odkaz:
https://doaj.org/article/30843b1fc9a94094b8ac48f07b7ad316
Autor:
Rebecca Halbgebauer, Ebru Karasu, Christian K. Braun, Annette Palmer, Sonja Braumüller, Anke Schultze, Fabian Schäfer, Sarah Bückle, Alica Eigner, Ulrich Wachter, Peter Radermacher, Ranillo R. G. Resuello, Joel V. Tuplano, Kristina Nilsson Ekdahl, Bo Nilsson, Milena Armacki, Alexander Kleger, Thomas Seufferlein, Miriam Kalbitz, Florian Gebhard, John D. Lambris, Martijn van Griensven, Markus Huber-Lang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Trauma represents a major socioeconomic burden worldwide. After a severe injury, hemorrhagic shock (HS) as a frequent concomitant aspect is a central driver of systemic inflammation and organ damage. The kidney is often strongly affected by traumatic
Externí odkaz:
https://doaj.org/article/2a44a84c5e6546358f4ea9327612f5b9