Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Annett M. Jacobi"'
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5776 (2009)
DNA-reactive B cells play a central role in systemic lupus erythematosus (SLE); DNA antibodies precede clinical disease and in established disease correlate with renal inflammation and contribute to dendritic cell activation and high levels of type 1
Externí odkaz:
https://doaj.org/article/1fcf5df24be640bfa9efb79da659f9e7
Autor:
Michela Spadaro, Tilman Schneider-Hohendorf, Volker Siffrin, Xavier Montalban, Felix Luessi, Ester Cantó, Reinhard Hohlfeld, Renaud Du Pasquier, Ralf Gold, Frauke Zipp, Antonio Bertolotto, Dennis Görlich, Christoph Kleinschnitz, Nicholas Schwab, Béatrice Pignolet, Johanna Breuer, David Brassat, Anita Posevitz-Fejfar, Tania Kümpfel, Heinz Wiendl, Annett M. Jacobi, Sven G. Meuth, Susanne Windhagen, Björn Tackenberg, Manuel Comabella, Ingrid Meinl
Publikováno v:
Europe PubMed Central
Background: Natalizumab treatment is associated with progressive multifocal leukoencephalopathy (PML) development. Treatment duration, prior immunosuppressant use, and JCV serostatus are currently used for risk stratification, but PML incidence stays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a07a77c462dda217134f13728d4066
https://doi.org/10.1177/1352458515607651
https://doi.org/10.1177/1352458515607651
Autor:
Iñaki Sanz, Tao Wang, William W. Freimuth, Cynthia Aranow, Weiqing Huang, Annett M. Jacobi, Meggan Mackay, Anne Davidson, Betty Diamond, Richard A. Furie
Publikováno v:
Arthritis & Rheumatism. 62:201-210
Objective To understand the effects of long-term BLyS inhibition in human systemic lupus erythematosus (SLE). Methods Seventeen patients with SLE who were enrolled in a clinical trial of belimumab, a BLyS-specific inhibitor, plus standard of care the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678b5bff07a93d82b5b6a6dd02fbcd75
https://doi.org/10.1002/art.27189
https://doi.org/10.1002/art.27189
Publikováno v:
Molecular Medicine. 14:675-681
Previous studies have shown that both murine and human anti-double-stranded DNA (anti-dsDNA) antibodies can develop from non-DNA–reactive B cells and suggest a crucial role for somatic mutation in dsDNA binding. However, since only a limited number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96320fffd774bff4e30df517869cffed
https://doi.org/10.2119/2008-00066.zhang
https://doi.org/10.2119/2008-00066.zhang
Autor:
Kerstin Hammer, Mareike Möllers, Walter Klockenbusch, Annett M. Jacobi, AC Warby, Ralf Schmitz, Susanne Amler, U Möllmann, Maria Karina Falkenberg
Publikováno v:
Ultraschall in der Medizin - European Journal of Ultrasound. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9f3a6ccb4d9673f0758a5968b7af2f8
https://doi.org/10.1055/s-0033-1355066
https://doi.org/10.1055/s-0033-1355066
Autor:
Liu Ting, Marcus Brand, Hermann Pavenstädt, Klaus Tiemann, Hideo A. Baba, Lu Ting, Dominik Kentrup, Alexander Grabner, Stefan Reuter, Giovana Seno Di Marco, Annett M. Jacobi
Publikováno v:
European heart journal. 32(15)
Aims Chronic kidney disease is directly associated with cardiovascular complications. Heart remodelling, including fibrosis, hypertrophy, and decreased vascularization, is frequently present in renal diseases. Our objective was to investigate the imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b2652fa3ad17e7ad5b9fef63d8be06
https://pubmed.ncbi.nlm.nih.gov/21138940
https://pubmed.ncbi.nlm.nih.gov/21138940
Publikováno v:
Journal of immunological methods. 363(2)
The prototypic autoimmune disease, SLE, is known to be associated with polyclonal B cell hyperreactivity. Developing an understanding of the complex nature of human B cell differentiation, largely through the application of multiparameter flow cytome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fb77141aadf2a7aae33eca74314185
https://pubmed.ncbi.nlm.nih.gov/20598709
https://pubmed.ncbi.nlm.nih.gov/20598709
Publikováno v:
Journal of autoimmunity. 33(3-4)
The present study was undertaken to determine whether germline encoded and polyreactive antibodies might be pathogenic and whether the breach of early tolerance checkpoints in systemic lupus erythematosus (SLE) might lead to a population of B cells e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca91df14b304bbea9ded854abe555e4
https://pubmed.ncbi.nlm.nih.gov/19398190
https://pubmed.ncbi.nlm.nih.gov/19398190
Autor:
Tao Wang, Cynthia Aranow, Annett M. Jacobi, Prameladevi Chinnasamy, Betty Diamond, Meggan Mackay, Jie Zhang
Publikováno v:
Journal of immunological methods. 338(1-2)
Autoreactive B cells play a central role in systemic lupus erythematosus (SLE). Characterization of DNA-reactive B cells in the blood of lupus patients has been limited by the low frequency of the population. Using a tetrameric configuration of a pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e4ca5691812917e9d33c1314d37dab
https://pubmed.ncbi.nlm.nih.gov/18713638
https://pubmed.ncbi.nlm.nih.gov/18713638
Autor:
Annett M, Jacobi, Marcus, Odendahl, Karin, Reiter, Anne, Bruns, Gerd R, Burmester, Andreas, Radbruch, Günter, Valet, Peter E, Lipsky, Thomas, Dörner
Publikováno v:
Arthritis and rheumatism. 48(5)
Disease activity in systemic lupus erythematosus (SLE) is usually assessed with complex disease activity scores comprising a variety of different parameters. In order to determine whether SLE disease activity correlates with abnormal B lymphocyte act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1097dd0321a05d014664afd5ad6704b1
https://pubmed.ncbi.nlm.nih.gov/12746906
https://pubmed.ncbi.nlm.nih.gov/12746906