Flow-cytometric assessment of cellular poly(ADP-ribosyl)ation capacity in peripheral blood lymphocytes

Autor: Hyland Paul, Thaa Bastian, Malaisé Muriel, Annett Kathryn, Liu Dan, Kunzmann Andrea, Barnett Yvonne, Bürkle Alexander

Publikováno v: Immunity & Ageing, Vol 3, Iss 1, p 8 (2006)

Abstract Background Poly(ADP-ribosyl)ation is a posttranslational modification of nuclear proteins catalysed by poly(ADP-ribose) polymerases (PARPs), using NAD+ as a substrate. Activation of PARP-1 is in immediate response to DNA damage generated by

Externí odkaz: https://doaj.org/article/9a7c59af641a40788a31a791f23374b4

Effects of a reduced oxygen tension culture system on human T cell clones as a function of in vitro age

Autor: Duggan, Orla, Hyland, Paul, Annett, Kathryn, Freeburn, Robin, Barnett, Christopher, Pawelec, Graham, Barnett, Yvonne ^∗

Publikováno v: In Experimental Gerontology 2004 39(4):525-530

An investigation of the processes that maintain genomic stability in T cells as a function of age in vitro and in vivo

Autor: Annett, Kathryn Elizabeth

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422886

Flow-cytometric assessment of cellular poly(ADP-ribosyl)ation capacity in peripheral blood lymphocytes.

Autor: Kunzmann A; Molecular Toxicology Group, Department of Biology, Box X911, University of Konstanz, D-78457 Konstanz, Germany., Liu D; Molecular Toxicology Group, Department of Biology, Box X911, University of Konstanz, D-78457 Konstanz, Germany., Annett K; Cancer and Ageing Research Group, School of Biomedical Sciences, University of Ulster, Coleraine, BT52 1SA, Northern Ireland, UK., Malaisé M; Molecular Toxicology Group, Department of Biology, Box X911, University of Konstanz, D-78457 Konstanz, Germany., Thaa B; Molecular Toxicology Group, Department of Biology, Box X911, University of Konstanz, D-78457 Konstanz, Germany., Hyland P; School of Biomedical and Natural Sciences, College of Science and Technology, Nottingham Trent University, Clifton Campus, NG11 8NS, Nottingham, UK., Barnett Y; Cancer and Ageing Research Group, School of Biomedical Sciences, University of Ulster, Coleraine, BT52 1SA, Northern Ireland, UK.; School of Biomedical and Natural Sciences, College of Science and Technology, Nottingham Trent University, Clifton Campus, NG11 8NS, Nottingham, UK., Bürkle A; Molecular Toxicology Group, Department of Biology, Box X911, University of Konstanz, D-78457 Konstanz, Germany.

Publikováno v: Immunity & ageing : I & A [Immun Ageing] 2006 Jul 19; Vol. 3, pp. 8. Date of Electronic Publication: 2006 Jul 19.