Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Annett Bleul"'
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3767 (2008)
BACKGROUND: It is unknown, on the proteomic level, whether the protein patterns of tumors change during metastasis or whether markers are present that allow metastases to be allocated to a specific tumor entity. The latter is of clinical interest if
Externí odkaz:
https://doaj.org/article/97e53b1cbc3546a6b029ccc80b982ed4
Autor:
Sebastian Scholl, Baerbel Spies-Weisshart, Christa Kunert, Ferdinand von Eggeling, Christian Melle, Annett Bleul, Klaus Höffken
Publikováno v:
Leukemia & Lymphoma. 48:2418-2423
FLT3 activating mutations can be detected in about 35% of acute myeloid leukemia (AML). FLT3 internal tandem duplications (FLT3-ITD) represent the majority of FLT3 mutations (25 - 30%) while FLT3-TKD (tyrosine kinase domain) mutations can be found in
Autor:
Annett Bleul, Roland M. du Bois, Frantisek Mrazek, Christian Melle, Vitezslav Kolek, Eva Kriegova, Beata Hutyrova, Ferdinand von Eggeling, Martin Petrek
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 173:1145-1154
Pulmonary sarcoidosis is a multisystem granulomatous disease with various clinical phenotypes. So far, there has been little information on protein patterns (PPs) of bronchoalveolar lavage fluid (BALF) from patients with sarcoidosis and no data are a
Autor:
Günther Ernst, Annett Bleul, Ferdinand von Eggeling, Christian Melle, Bettina Schimmel, Ralf Bogumil
Publikováno v:
PROTEOMICS. 6:2600-2608
Although colorectal cancer is one of the best-characterized tumors with regard to the multistep progression, it remains one of the most frequent and deadly neoplasms. For a better understanding of the molecular mechanisms behind the process of tumori
Autor:
Bärbel Spies-Weißhart, Annett Bleul, Dominik Driesch, Martin Kaatz, Uwe Wollina, Christian Melle, Ferdinand von Eggeling, Niko Escher
Publikováno v:
European Journal of Cancer. 42:249-255
Cutaneous T-cell lymphomas (CTCL) are characterized by malignant proliferation of skin homing T-cells. Although prognosis is generally good, reliable markers are needed to identify patients at risk for a more aggressive course. ProteinChip (SELDI) te
Autor:
von Eggeling F, Richter Kk, Bettina Schimmel, Christian Melle, Daffner W, Annett Bleul, Günther Ernst, Uwe Claussen, Merten Hommann, Utz Settmacher, Roland Kaufmann
Publikováno v:
Journal of Proteome Research. 4:1799-1804
We analyzed 74 cryostat sections of central gastric tumor, tumor margin, and normal gastric epithelium using ProteinChip Arrays and SELDI-TOF MS. One peak was significantly down-regulated in tumor tissue (P = 1.43 × 10-6) and identified as pepsinoge
Autor:
Andreas Wiesner, Ferdinand von Eggeling, Sven Koscielny, Christian Melle, Ursula Möller, Günther Ernst, Dirk Osterloh, Bettina Schimmel, Annett Bleul, Ralf Bogumil, Karl-Jürgen Halbhuber
Publikováno v:
Cancer Research. 64:4099-4104
Biomarkers are needed to elucidate the biological background and to improve the detection of cancer. Therefore, we have analyzed laser-microdissected cryostat sections from head and neck tumors and adjacent mucosa on ProteinChip arrays. Two different
Autor:
Susanne Michel, Anita Heller, Ferdinand von Eggeling, Christian Melle, Annett Bleul, Ivan F. Loncarevic
Publikováno v:
ResearcherID
For chromosomal analysis in tumor genetics, cells from blood and bone marrow are prepared and preserved virtually indefinitely in Carnoy's fixative (methanol/acetic acid). Numerous samples are stored unvalued in hospitals and institutes worldwide. We
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3767 (2008)
PLoS ONE
PLoS ONE
Background It is unknown, on the proteomic level, whether the protein patterns of tumors change during metastasis or whether markers are present that allow metastases to be allocated to a specific tumor entity. The latter is of clinical interest if t
Autor:
Annett Bleul, Heike Thieme, Klaus Felix, Horst Täubig, Merten Hommann, Wolfgang Daffner, Konrad Klaus Richter, Roland Kaufmann, Günther Ernst, Daniel Hartmann, Ferdinand von Eggeling, Thomas Manger, Niko Escher, Christian Melle, Uwe Claussen, Utz Settmacher, Helmut Friess, Bettina Schimmel
Publikováno v:
Clinical chemistry. 53(4)
Background: Patients with pancreatic adenocarcinomas have a poor prognosis because of late clinical manifestation and the tumor’s aggressive nature. We used proteomic techniques to search for markers of pancreatic carcinoma. Methods: We performed p