ACTIV trials: cross-trial lessons learned for master protocol implementation

Autor: Maryam Keshtkar-Jahromi, Stacey J. Adam, Indira Brar, Lucy K. Chung, Judith S. Currier, Eric S. Daar, Victoria J. Davey, Eileen T. Denning, Annetine C. Gelijns, Elizabeth S. Higgs, Prasanna Jagannathan, Arzhang Cyrus Javan, Tomas O. Jensen, Nikolaus Jilg, Ioannis Kalomenidis, Peter Kim, Seema U. Nayak, Matthew Newell, Babafemi O. Taiwo, Tammy Yokum, Yvette Delph

Publikováno v: Journal of Clinical and Translational Science, Vol 8 (2024)

The United States Government (USG) public-private partnership “Accelerating COVID-19 Treatment Interventions and Vaccines” (ACTIV) was launched to identify safe, effective therapeutics to treat patients with Coronavirus Disease 2019 (COVID-19) an

Externí odkaz: https://doaj.org/article/b429d74352644bba8ed889493a0a3109

Rationale and design of a randomized trial evaluating an external support device for saphenous vein coronary grafts

Autor: Emilia Bagiella, John D. Puskas, Alan J. Moskowitz, Annetine C. Gelijns, John H. Alexander, Jagat Narula, Peter K. Smith, Kelley Hutcheson, Helena L. Chang, James S. Gammie, Alexander Iribarne, Mary E. Marks, Yuliya Vengrenyuk, Keisuke Yasumura, Samantha Raymond, Bradley S. Taylor, Orit Yarden, Eyal Orion, François Dagenais, Gorav Ailawadi, Michael W.A. Chu, Lopa Gupta, Ronald G. Levitan, Judson B. Williams, Juan A. Crestanello, Mariell Jessup, Eric A. Rose, Vincent Scavo, Michael A. Acker, Marc Gillinov, Patrick T. O'Gara, Pierre Voisine, Michael J. Mack, Daniel J. Goldstein

Publikováno v: Am Heart J

BACKGROUND: Coronary artery bypass grafting (CABG) is the most common revascularization approach for the treatment of multi-vessel coronary artery disease. While the internal mammary artery is nearly universally used to bypass the left anterior desce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732f6daee28264d67111c2a52e79a554
https://doi.org/10.1016/j.ahj.2021.12.009

Pacemaker implantation associated with tricuspid repair in the setting of mitral valve surgery: Insights from a Cardiothoracic Surgical Trials Network randomized trial

Autor: Gorav Ailawadi, Pierre Voisine, Samantha Raymond, Annetine C. Gelijns, Alan J. Moskowitz, Volkmar Falk, Jessica R. Overbey, Michael W.A. Chu, Michael J. Mack, Michael E. Bowdish, Markus Krane, Babatunde Yerokun, Lenard Conradi, Steven F. Bolling, Marissa A. Miller, Wendy C. Taddei-Peters, Kathleen N. Fenton, Neal O. Jeffries, Robert S. Kramer, Arnar Geirsson, Ellen G. Moquete, Karen O'Sullivan, Jonathan Hupf, Judy Hung, Friedhelm Beyersdorf, Emilia Bagiella, James S. Gammie, Patrick T. O'Gara, Alexander Iribarne, Michael A. Borger, Marc Gillinov

Publikováno v: The Journal of Thoracic and Cardiovascular Surgery.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5465c5fe36471123827082c1b64f77a4
https://doi.org/10.1016/j.jtcvs.2022.11.031

Characteristics of Postoperative Atrial Fibrillation and the Effect of Posterior Pericardiotomy

Autor: Roberto Perezgrovas-Olaria, David Chadow, Christopher Lau, Mohamed Rahouma, Giovanni Jr Soletti, Gianmarco Cancelli, Lamia Harik, Arnaldo Dimagli, Lisa Q. Rong, Marc Gillinov, Niv Ad, Michael DiMaio, Annetine C. Gelijns, Tommaso Sanna, Stephen Fremes, Filippo Crea, Leonard Girardi, Mario Gaudino

Publikováno v: The Annals of Thoracic Surgery.

Postoperative atrial fibrillation (POAF) is a frequent complication of cardiac surgery. However, only a few detailed descriptions of the arrhythmia have been reported. We aim to describe the characteristics, outcomes, and variables associated with PO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adabc339f0753b25b22fedb664c98325
https://doi.org/10.1016/j.athoracsur.2022.11.007

Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19:A Randomized Controlled Trial

Autor: Christina, Barkauskas, Eleftherios, Mylonakis, Garyfallia, Poulakou, Barnaby E, Young, David M, Vock, Lianne, Siegel, Nicole, Engen, Greg, Grandits, Nilima R, Mosaly, Andrew M, Vekstein, Ralph, Rogers, Fadi, Shehadeh, Matthew, Kaczynski, Evangelia K, Mylona, Konstantinos N, Syrigos, Vasiliki, Rapti, David C, Lye, Diong Shiau, Hui, Lindsay, Leither, Kirk U, Knowlton, Mamta K, Jain, Rubria, Marines-Price, Alice, Osuji, J Scott, Overcash, Ioannis, Kalomenidis, Zafeiria, Barmparessou, Michael, Waters, Karla, Zepeda, Peter, Chen, Sam, Torbati, Francis, Kiweewa, Nicholus, Sebudde, Eyad, Almasri, Alyssa, Hughes, Sanjay R, Bhagani, Alison, Rodger, Uriel, Sandkovsky, Robert L, Gottlieb, Eriobu, Nnakelu, Barbara, Trautner, Vidya, Menon, Joseph, Lutaakome, Michael, Matthay, Philip, Robinson, Konstantinos, Protopapas, Nikolaos, Koulouris, Ivan, Kimuli, Amiran, Baduashvili, Dominique L, Braun, Huldrych F, Günthard, Srikanth, Ramachandruni, Robert, Kidega, Kami, Kim, Timothy J, Hatlen, Andrew N, Phillips, Daniel D, Murray, Tomas O, Jensen, Maria L, Padilla, Evan X, Accardi, Katy, Shaw-Saliba, Robin L, Dewar, Marc, Teitelbaum, Ven, Natarajan, Sylvain, Laverdure, Helene C, Highbarger, M Tauseef, Rehman, Susan, Vogel, David, Vallée, Page, Crew, Negin, Atri, Adam J, Schechner, Sarah, Pett, Fleur, Hudson, Jonathan, Badrock, Giota, Touloumi, Samuel M, Brown, Wesley H, Self, Crystal M, North, Adit A, Ginde, Christina C, Chang, Anthony, Kelleher, Stephanie, Nagy-Agren, Shikha, Vasudeva, David, Looney, Hien H, Nguyen, Adriana, Sánchez, Amy C, Weintrob, Birgit, Grund, Shweta, Sharma, Cavan S, Reilly, Roger, Paredes, Agnieszka, Bednarska, Norman P, Gerry, Abdel G, Babiker, Victoria J, Davey, Annetine C, Gelijns, Elizabeth S, Higgs, Virginia, Kan, Gail, Matthews, B Taylor, Thompson, Philippe, Legenne, Richa, Chandra, H Clifford, Lane, James D, Neaton, Richard, Williams

Publikováno v: ACTIV-3/TICO Study Group*, Nielsen, H, Thisted, R K, Petersen, K T & Juhl, M R 2022, ' Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 : A Randomized Controlled Trial ', Annals of Internal Medicine, vol. 175, no. 9, pp. 1266-1274 . https://doi.org/10.7326/M22-1503

BACKGROUND: Ensovibep (MP0420) is a designed ankyrin repeat protein, a novel class of engineered proteins, under investigation as a treatment of SARS-CoV-2 infection. OBJECTIVE: To investigate if ensovibep, in addition to remdesivir and other standar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d142eddc0f692abd7c33d99b51bb4e
https://vbn.aau.dk/da/publications/828dfc6c-d4d0-47b8-a749-9cc4901459a8