Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Annemieke W. Plug"'
The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes
Autor:
M S Meyn, E R Christenson, E E Brainerd, Terry Ashley, Elaine M. Taylor, Annemieke W. Plug, Nicola J. Bentley, Gail Flaggs, D A Holtzman, Antony M. Carr, S B Moss, Merl F. Hoekstra, Kathleen S. Keegan
Publikováno v:
Genes & Development. 10:2423-2437
A number of cell-cycle checkpoint genes have been shown to play important roles in meiosis. We have characterized the human and mouse counterpart of the Schizosaccharomyces pombe Rad3 protein, named Atr (for ataxia-telangiectasia- and rad3-related),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c814f5b9511190a76b430db9d9e9181
https://doi.org/10.1101/gad.10.19.2423
https://doi.org/10.1101/gad.10.19.2423
Autor:
Norman Arnheim, Merrilee Robatzek, Bronner C Eric, Jian Yu, Terry Ashley, Lin Zhang, R. Michael Liskay, Richard A. Flavell, Eileen A. Elliott, Gwynedd Warren, Sean M. Baker, Annemieke W. Plug
Publikováno v:
Cell. 82(2):309-319
Using gene targeting in embryonic stem cells, we have derived mice with a null mutation in a DNA mismatch repair gene homolog, PMS2. We observed microsatellite instability in the male germline, in tail, and in tumor DNA of PMS2-deficient animals. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400f2a3f12881bf138aae6df19ddebf0
Publikováno v:
Chromosome Research. 5:66-68
A.H.F.M. Peters (corresponding author), A.W. Plug, M.J. van Vugt and P. de Boer are at the Department of Genetics, Wageningen Institute of Animal Sciences, Wageningen Agricultural University, Dreijenlaan 2, NL-6703 HA Wageningen, The Netherlands. Tel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9d2bdf84299f17154c836aba2dbbf16
https://doi.org/10.1023/a:1018445520117
https://doi.org/10.1023/a:1018445520117
Autor:
Jennifer I. Koop, Aloysius J. Klingelhutz, Terri Sundsvold, Michelle A. Wurscher, James K. McDougall, Annemieke W Plug-DeMaggio
Publikováno v:
Oncogene. 23(20)
Progression to advanced-stage cervical carcinomas is characterized by a recurrent pattern of chromosomal rearrangements. Structural chromosome rearrangements are generated through the fusion of broken chromosome ends. These chromosome breaks may be i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474fb778bca27f25a6dc2acde5499db3
https://pubmed.ncbi.nlm.nih.gov/15077181
https://pubmed.ncbi.nlm.nih.gov/15077181
Publikováno v:
Oncogene. 21(49)
Expression of the human papillomavirus type 16 E6 and E7 oncogenes initiates and maintains abnormal cell replication, by interacting with the p53 and retinoblastoma (Rb) gene products. Subsequent changes in host cell gene expression, as a consequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800dc67b7fb8e511c40122e51d7a5e7a
https://pubmed.ncbi.nlm.nih.gov/12386813
https://pubmed.ncbi.nlm.nih.gov/12386813
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(10)
Bloom’s syndrome (BS) is a rare autosomal recessive disorder of humans characterized by severe pre- and postnatal growth deficiency, immunodeficiency, genomic instability, and a predisposition to a wide variety of neoplasms. The genomic instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfbcfab906268a3e0f69dbb24327810
https://pubmed.ncbi.nlm.nih.gov/10318934
https://pubmed.ncbi.nlm.nih.gov/10318934
Autor:
Antoine H.F.M. Peters, P. de Boer, Merl F. Hoekstra, Terry Ashley, Annemieke W. Plug, Kathleen S. Keegan, Yang Xu, David Baltimore
Publikováno v:
Nature genetics. 17(4)
ATM is a member of the phosphatidylinositol 3-kinase (PIK)like kinases, some of which are active in regulating DNA damage-induced mitotic cell-cycle checkpoints1,2. ATM also plays a role in meiosis. Spermatogenesis in Atm−/− male mice is disrupte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0b7bce51a7c3f62fe49a7cf7719e03
https://pubmed.ncbi.nlm.nih.gov/9398850
https://pubmed.ncbi.nlm.nih.gov/9398850
Publikováno v:
Chromosome Research, 5, 313-324
Chromosome Research 5 (1997)
Chromosome Research 5 (1997)
Mice that are double heterozygous for the semi-identical T(1;13)70H and T(1;13)1Wa reciprocal translocations display a great variation in male fertility. The synaptic behaviour of the different translocation chromosomes of adult males was studied in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8118f67f8d62c9d858be8a8b26d4b61c
https://pubmed.ncbi.nlm.nih.gov/9292236
https://pubmed.ncbi.nlm.nih.gov/9292236
Autor:
David M. Livingston, Terry Ashley, Annemieke W. Plug, Jean Feunteun, Yonghong Xiao, David R. Weaver, Ralph Scully, Junjie Chen
Publikováno v:
Cell. 88(2)
BRCA1 immunostaining reveals discrete, nuclear foci during S phase of the cell cycle. Human Rad51, a homolog of bacterial RecA, behaves similarly. The two proteins were found to colocalize in vivo and to coimmunoprecipitate. BRCA1 residues 758–1064
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d850fa08978e085af5fbb034945238
https://pubmed.ncbi.nlm.nih.gov/9008167
https://pubmed.ncbi.nlm.nih.gov/9008167
Autor:
Annemieke W. Plug, Terry Ashley
Meiotic division comprises a complex series of events, many of which are unique in the life cycle of the organism. The process utilizes both proteins that participate in normal mitotic cell cycle progression and DNA damage repair and proteins express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::739ed58cd7c5f59bf8c1efc94a35a9bc
https://doi.org/10.1016/s0070-2153(08)60175-1
https://doi.org/10.1016/s0070-2153(08)60175-1
