Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Annemieke Madder"'
Autor:
Penthip Muangkaew, Vic De Roo, Lu Zhou, Léa Girard, Catherine Cesa-Luna, Monica Höfte, René De Mot, Annemieke Madder, Niels Geudens, José C. Martins
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14302 (2023)
In Pseudomonas lipopeptides, the D-configuration of amino acids is generated by dedicated, dual-function epimerization/condensation (E/C) domains. The increasing attention to stereochemistry in lipopeptide structure elucidation efforts has revealed m
Externí odkaz:
https://doaj.org/article/d68069bd9b27454ba49d3a2ef8e152fb
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-9 (2021)
Proximity-based ligations commonly require an external stimulus such as a catalyst or irradiation, or highly reactive functional groups. Here the reaction of alpha effect nucleophiles and 2,5-dioxopentanyl derivatives allows direct proximity-based li
Externí odkaz:
https://doaj.org/article/a316cacbdb304eccb7c8da176865c12b
Autor:
Vic De Roo, Yentl Verleysen, Benjámin Kovács, Matthias De Vleeschouwer, Penthip Muangkaew, Léa Girard, Monica Höfte, René De Mot, Annemieke Madder, Niels Geudens, José C. Martins
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Cyclic lipopeptides (CLiPs) are secondary metabolites secreted by a range of bacterial phyla. CLiPs from Pseudomonas in particular, display diverse structural variations in terms of the number of amino acid residues, macrocycle size, amino a
Externí odkaz:
https://doaj.org/article/245622bbff19407ba87dc418b727cb5f
Autor:
Laia Miret-Casals, Sander Van De Putte, Dorien Aerssens, Julien Diharce, Pascal Bonnet, Annemieke Madder
Publikováno v:
Frontiers in Chemistry, Vol 9 (2022)
Using a coiled-coil peptide dimer as a model system to explore furan reactivity, we describe novel cross-link partners of furan warheads for site-specific cross-linking. We demonstrate that replacement of weak interhelical ionic contacts with a furan
Externí odkaz:
https://doaj.org/article/744096a0a6d14f359007281f58d9bc59
Autor:
Matthias De Vleeschouwer, Tim Van Kersavond, Yentl Verleysen, Davy Sinnaeve, Tom Coenye, José C. Martins, Annemieke Madder
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Cyclic lipo(depsi)peptides (CLiPs) from Pseudomonas constitute a class of natural products involved in a broad range of biological functions for their producers. They also display interesting antimicrobial potential including activity against Gram-po
Externí odkaz:
https://doaj.org/article/5fcc3c097f9a4e2398094cc836ba9b3f
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The generation of PNA-decorated gold nanoparticles (AuNPs) has revealed to be more difficult as compared to the generation of DNA-functionalized ones. The less polar nature of this artificial nucleic acid system and the associated tendency of the neu
Externí odkaz:
https://doaj.org/article/c68efa6231ff43bdb5b6d870c4e6ad86
Publikováno v:
Molecules, Vol 27, Iss 3, p 778 (2022)
Singlet oxygen (1O2) is the excited state of ground, triplet state, molecular oxygen (O2). Photosensitized 1O2 has been extensively studied as one of the reactive oxygen species (ROS), responsible for damage of cellular components (protein, DNA, lipi
Externí odkaz:
https://doaj.org/article/dd0ed8f456b248e284c5628f73b15d96
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4522 (2020)
Aptamers are short single stranded DNA or RNA oligonucleotides that can recognize analytes with extraordinary target selectivity and affinity. Despite their promising properties and diagnostic potential, the number of commercial applications remains
Externí odkaz:
https://doaj.org/article/341532785caf41d5ad7cba5429888a50
Publikováno v:
Molecules, Vol 25, Iss 6, p 1296 (2020)
MicroRNAs (miRNAs or miRs) are small noncoding RNAs involved in the fine regulation of post-transcriptional processes in the cell. The physiological levels of these short (20−22-mer) oligonucleotides are important for the homeostasis of the organis
Externí odkaz:
https://doaj.org/article/84d7ead60cef45e59fa5f21a2b76b05c
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 2566-2572 (2014)
Functionalized oligonucleotides have recently gained increased attention for incorporation in modified nucleic acid structures both for the design of aptamers with enhanced binding properties as well as the construction of catalytic DNA and RNA. As a
Externí odkaz:
https://doaj.org/article/44284464eb524111a6823a5ece37ba8c