Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Annemieke J.M. de Ruijter"'
Autor:
André B.P. van Kuilenburg, Jerry Hoebink, René Leen, Annemieke J.M. de Ruijter, Huib N. Caron
Publikováno v:
Cancer letters, 233(2), 240-246. Elsevier Ireland Ltd
Additive to synergistic induction of apoptosis has been reported as a result of sequential incubation of cancer cells with a histone deacetylase inhibitor (HDACi) and gemcitabine (dFdC), a deoxycytidine analogue with proven anti-tumour activity. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01320dfd61c210126053b27d5b96ae02
https://doi.org/10.1016/j.canlet.2005.03.016
https://doi.org/10.1016/j.canlet.2005.03.016
Autor:
Rutger Meinsma, Stephan Kemp, Annemieke J.M. de Ruijter, André B.P. van Kuilenburg, Peter Bosma, Huib N. Caron
Publikováno v:
Experimental cell research, 309(2), 451-467. Academic Press Inc.
Neuroblastoma is a childhood tumor with a poor survival in advanced stage disease despite intensive chemotherapeutic regimes. The new historic deacetylase (HDAC) inhibitor BL1521 has shown promising results in neuroblastoma. Inhibition of HDAC result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68714d545b9af9b89fe3904560370434
https://doi.org/10.1016/j.yexcr.2005.06.024
https://doi.org/10.1016/j.yexcr.2005.06.024
Autor:
Rutger Meinsma, Annemieke J.M. de Ruijter, André B.P. van Kuilenburg, Judith O. Kaufmann, Stephan Kemp, Huib N. Caron, Gert Jan Kramer
Publikováno v:
Biochemical pharmacology, 68(7), 1279-1288. Elsevier Inc.
Neuroblastoma is a childhood cancer arising from the sympathetic nervous system. Disseminated neuroblastoma has a poor prognosis despite intensive multimodality treatment. Histone deacetylases (HDACs) were recently discovered as a potential target fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4f7756baf048bf28c41a390c23ef32
https://doi.org/10.1016/j.bcp.2004.05.010
https://doi.org/10.1016/j.bcp.2004.05.010
Autor:
Albert H. van Gennip, Annemieke J.M. de Ruijter, André B.P. van Kuilenburg, Huib N. Caron, Stephan Kemp
Publikováno v:
Biochemical Journal. 370:737-749
Transcriptional regulation in eukaryotes occurs within a chromatin setting, and is strongly influenced by the post-translational modification of histones, the building blocks of chromatin, such as methylation, phosphorylation and acetylation. Acetyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce1ab5bdc692f2215f26edfdf45307f
https://doi.org/10.1042/bj20021321
https://doi.org/10.1042/bj20021321
Autor:
Annemieke J.M. de Ruijter, Chris van Bree, André B.P. van Kuilenburg, Huib N. Caron, Krista Ouwehand
Publikováno v:
FEBS letters, 579(6), 1523-1528. Wiley-Blackwell
Histone deacetylase inhibitors (HDACi) have been discovered as potential drugs for cancer treatment. The effect of BL1521, a novel HDACi, on the cell cycle distribution and the induction of apoptosis was investigated in a panel of MYCN single copy an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71195e5ec29301a08c863b451c76c775