Astrocytic ceramide as possible indicator of neuroinflammation

Autor: Nienke M. de Wit, Sandra den Hoedt, Pilar Martinez-Martinez, Annemieke J. Rozemuller, Monique T. Mulder, Helga E. de Vries

Publikováno v: Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-11 (2019)

Abstract Background Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease dementia (PDD), and frontotemporal lobar dementia (FTLD) are characterized by progressive neuronal loss but differ in their underlying pathologic

Externí odkaz: https://doaj.org/article/617ced624c34492ea11378ffd276a072

Different curcumin forms selectively bind fibrillar amyloid beta in post mortem Alzheimer’s disease brains: Implications for in-vivo diagnostics

Autor: Jurre den Haan, Tjado H. J. Morrema, Annemieke J. Rozemuller, Femke H. Bouwman, Jeroen J. M. Hoozemans

Publikováno v: Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-12 (2018)

Abstract The combined fluorescent and Aβ-binding properties of the dietary spice curcumin could yield diagnostic purpose in the search for a non-invasive Aβ-biomarker for Alzheimer’s disease (AD). However, evidence on the binding properties of cu

Externí odkaz: https://doaj.org/article/75dd0001f4e54955828b760001c44bea

Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies

Autor: Frederique J, Hart de Ruyter, Tjado H J, Morrema, Jurre, den Haan, Jos W R, Twisk, Johannes F, de Boer, Philip, Scheltens, Baayla D C, Boon, Dietmar R, Thal, Annemieke J, Rozemuller, Frank D, Verbraak, Femke H, Bouwman, Jeroen J M, Hoozemans

Publikováno v: Acta neuropathologica.

The retina is a potential source of biomarkers for the detection of neurodegenerative diseases. Accumulation of phosphorylated tau (p-tau) in the brain is a pathological feature characteristic for Alzheimer's disease (AD) and primary tauopathies. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fd7156c8be0d8c2b29bbd8e3c136969d
https://pubmed.ncbi.nlm.nih.gov/36562817

LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study

Autor: Marialuisa Quadri, Wim Mandemakers, Martyna M Grochowska, Roy Masius, Hanneke Geut, Edito Fabrizio, Guido J Breedveld, Demy Kuipers, Michelle Minneboo, Leonie J M Vergouw, Ana Carreras Mascaro, Ekaterina Yonova-Doing, Erik Simons, Tianna Zhao, Alessio B Di Fonzo, Hsiu-Chen Chang, Piero Parchi, Marta Melis, Leonor Correia Guedes, Chiara Criscuolo, Astrid Thomas, Rutger W W Brouwer, Daphne Heijsman, Angela M T Ingrassia, Giovanna Calandra Buonaura, Janneke P Rood, Sabina Capellari, Annemieke J Rozemuller, Marianna Sarchioto, Hsin Fen Chien, Nicola Vanacore, Simone Olgiati, Yah-Huei Wu-Chou, Tu-Hsueh Yeh, Agnita J W Boon, Susanne E Hoogers, Mehrnaz Ghazvini, Arne S IJpma, Wilfred F J van IJcken, Marco Onofrj, Paolo Barone, David J Nicholl, Andreas Puschmann, Michele De Mari, Anneke J Kievit, Egberto Barbosa, Giuseppe De Michele, Danielle Majoor-Krakauer, John C van Swieten, Frank J de Jong, Joaquim J Ferreira, Giovanni Cossu, Chin-Song Lu, Giuseppe Meco, Pietro Cortelli, Wilma D J van de Berg, Vincenzo Bonifati, Anneke J.A. Kievit, Agnita J.W. Boon, Janneke P.A Rood, Leonie J.M. Vergouw, Frank J. de Jong, John C. van Swieten, Francesco U.S. Mattace-Raso, Klaus L. Leenders, Joaquim J. Ferreira, Emil Ygland, Christer Nilsson, Hsin F. Chien, Laura Bannach Jardim, Carlos R.M. Rieder, Leonardo Lopiano, Cristina Tassorelli, Claudio Pacchetti, Giulio Riboldazzi, Giorgio Bono, Cristoforo Comi, Alessandro Padovani, Barbara Borroni, Francesco Raudino, Emiliana Fincati, Michele Tinazzi, Alberto Bonizzato, Carlo Ferracci, Alessio Dalla Libera, Giovanni Abbruzzese, Roberto Marconi, Marco Guidi, Giovanni Fabbrini, Alfredo Berardelli, Fabrizio Stocchi, Laura Vacca, Marina Picillo, Claudia Dell'Aquila, Gianni Iliceto, Vincenzo Toni, Giorgio Trianni, Monica Gagliardi, Grazia Annesi, Aldo Quattrone, Valeria Saddi, Gianni Cossu, Maurizio Melis

Publikováno v: The Lancet Neurology, 17, 597-608. Lancet Publishing Group
The Lancet Neurology, 17(7), 597-608. Lancet Publishing Group
Lancet Neurology, 17(7), 597-608. Lancet Publishing Group
International Parkinsonism Genetics Network 2018, ' LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies : a genome-wide linkage and sequencing study ', The Lancet Neurology, vol. 17, no. 7, pp. 597-608 . https://doi.org/10.1016/S1474-4422(18)30179-0

Summary Background Most patients with Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies do not carry mutations in known disease-causing genes. The aim of this study was to identify a novel gene implicated in the develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e6386fbddbbc669fd451323d5f8502
https://pure.eur.nl/en/publications/3a0201b7-ab58-4167-8432-f3c6b73b8801

Association of the PRNP regulatory region polymorphisms with the occurrence of sporadic Creutzfeldt-Jakob disease

Autor: Jolanta, Bratosiewicz-Wąsik, Joanna, Smoleń-Dzirba, Cezary, Watała, Annemieke J, Rozemuller, Casper, Jansen, Wim, Spliet, Gerard H, Jansen, Tomasz J, Wąsik, Paweł P, Liberski

Publikováno v: Folia neuropathologica. 50(1)

The prion protein (PrP) plays a central role in the pathogenesis of Creutzfeldt-Jakob disease and other transmissible spongiform encephalopathies (TSEs). Mutations in the coding region of the prion protein (PRNP) gene are linked to inherited forms of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d2a1a68b0f81c35389b927fde9ac168
https://pubmed.ncbi.nlm.nih.gov/22505365