Are patients with stage III non-small cell lung cancer treated with chemoradiotherapy at risk for cardiac events? Results from a retrospective cohort study

Autor: Juliette Degens, D De Ruysscher, Ruud Houben, Bastiaan Kietselaer, Gerben Bootsma, Lizza Hendriks, Ellen Huijbers, Annemie Schols, Anne-Marie C Dingemans

Publikováno v: BMJ Open, Vol 10, Iss 9 (2020)

Objectives Dyspnoea is one of the symptoms frequently encountered after treatment with chemoradiotherapy (CRT) in stage III non-small cell lung cancer (NSCLC). Long-term data on mild to moderately severe cardiac events as underlying cause of dyspnoea

Externí odkaz: https://doaj.org/article/10315a0b5ae54b35bed36de7c048a376

A novel in vitro model for the assessment of postnatal myonuclear accretion

Autor: Anita Kneppers, Lex Verdijk, Chiel de Theije, Mark Corten, Ellis Gielen, Luc van Loon, Annemie Schols, Ramon Langen

Publikováno v: Skeletal Muscle, Vol 8, Iss 1, Pp 1-13 (2018)

Abstract Background Due to the post-mitotic nature of myonuclei, postnatal myogenesis is essential for skeletal muscle growth, repair, and regeneration. This process is facilitated by satellite cells through proliferation, differentiation, and subseq

Externí odkaz: https://doaj.org/article/6eacc5d3980f41c58da9f230ef199131

Evidence-based practice within nutrition: what are the barriers for improving the evidence and how can they be dealt with?

Autor: Martine Laville, Berenice Segrestin, Maud Alligier, Cristina Ruano-Rodríguez, Lluis Serra-Majem, Michael Hiesmayr, Annemie Schols, Carlo La Vecchia, Yves Boirie, Ana Rath, Edmund A. M. Neugebauer, Silvio Garattini, Vittorio Bertele, Christine Kubiak, Jacques Demotes-Mainard, Janus C. Jakobsen, Snezana Djurisic, Christian Gluud

Publikováno v: Trials, Vol 18, Iss 1, Pp 1-9 (2017)

Abstract Background Evidence-based clinical research poses special barriers in the field of nutrition. The present review summarises the main barriers to research in the field of nutrition that are not common to all randomised clinical trials or tria

Externí odkaz: https://doaj.org/article/f66faeb18b5e4ba39c4a0508a17ca523

Targeted medical nutrition for cachexia in chronic obstructive pulmonary disease: a randomized, controlled trial

Autor: Philip C. Calder, Alessandro Laviano, Fredrik Lonnqvist, Maurizio Muscaritoli, Maria Öhlander, Annemie Schols

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle
Journal of cachexia, sarcopenia and muscle, 9(1), 28-40. Wiley
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 1, Pp 28-40 (2018)

BackgroundCachectic patients with chronic obstructive pulmonary disease (COPD) may benefit from nutritional support. This double-blind, randomized, controlled trial evaluated the safety and efficacy of targeted medical nutrition (TMN) vs. an isocalor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b51ddc5b3de0a9f396b72ac08659a85d
http://europepmc.org/articles/PMC5803606

Inactivation of glycogen synthase kinase 3β (GSK-3β) enhances skeletal muscle oxidative metabolism

Autor: Alexander Remels, Koen Verhees, Harry Gosker, Annemie Schols, Ramon Langen

Publikováno v: 6.4 Genes and Environment.

Background: Linked to physical inactivity, loss of muscle oxidative metabolism is a consistent finding in COPD. Evidence in non-muscle cells shows that glycogen synthase kinase-3β (GSK-3β) represses mitochondrial biogenesis and inhibits PPAR-γ co-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f21dc067955a795604271050d5132ffe
https://doi.org/10.1183/13993003.congress-2015.pa1226