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Autor:
Jan A. Gossen, Lenita Timmer-Hellings, Han Gerrits, Nicole E. C. Bakker, Annemie M. C. B. Koonen-Reemst, Maarten D. Sollewijn Gelpke, Marc C. B. C. Paradé
Publikováno v:
Reproduction, fertility, and development. 26(2)
Liver receptor homologue-1 (LRH-1) is an orphan nuclear receptor that has been implicated in steroid hormone biosynthesis and fertility. Herein we describe a transgenic inducible short hairpin (sh) RNA mouse model that was used to study the effect of