Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Annemarie Lekkerkerker"'
Autor:
Erik H.J. Danen, B. Ewa Snaar-Jagalska, Gabri van der Pluijm, Bob van de Water, Jiangling Xiong, Zuzanna Baranski, Esther I. Verhoef, A. Marije M. Hoogland, Geert J.L.H. van Leenders, Guido Jenster, Richard Janssen, Annemarie Lekkerkerker, Hans de Bont, Steffen Nijhoff, Geertje van der Horst, Shuning He, Veerander P.S. Ghotra
Supplemental Figures S1-S5 Figure S1. Whole organism automated bioimaging assay differentiates between androgen independent / metastatic and androgen-dependent / non-metastatic prostate cancer cells. Figure S2. SYK depletion attenuates PC3 disseminat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0f09c98c42bfca7990d71c8d583d38
https://doi.org/10.1158/0008-5472.22405436
https://doi.org/10.1158/0008-5472.22405436
Autor:
Lucinda Tam, Annemarie Lekkerkerker, Jeffrey Eastham-Anderson, Melanie Domeyer, Brent S. McKenzie, Azadeh Hadadianpour, Eugene Varfolomeev, Arna Katewa, Steven Do, A. Francesca Setiadi, Wyne P. Lee, Joy Drobnick, Andres Paler-Martinez, Rajita Pappu, Katherine Bao, Marian C. Bryan, Alfred Wong, James J. Crawford, Cesar A. Corzo, Vida Asghari, Sha Klabunde, Vladimir Ramirez-Carrozi, Jodie Pang, Jason A. Hackney, Hans Brightbill, Christopher Dela Cruz, Ross Francis, Yonglian Sun, Merone Roose-Girma, Claire Emson, Wendy B. Young, Michael J. Townsend, James R. Kiefer, Cary D. Austin, Swathi Sujatha-Bhaskar, Emily Hunley, Nico Ghilardi, Daqi Xu, Søren Warming, Kate Senger, Zhiyu Huang, Vivian W. C. Lau, Domagoj Vucic, Ali A. Zarrin, Eric Suto
Publikováno v:
Science signaling. 13(634)
The dysregulation of multiple signaling pathways, including those through endosomal Toll-like receptors (TLRs), Fc gamma receptors (FcγR), and antigen receptors in B cells (BCR), promote an autoinflammatory loop in systemic lupus erythematosus (SLE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df56c99041e31c3d42be9d115b0561d
https://pubmed.ncbi.nlm.nih.gov/32487715
https://pubmed.ncbi.nlm.nih.gov/32487715
Autor:
Yehong Wang, Annemarie Lekkerkerker, Frank Wagner, C Li, A Dash, John C. Mansfield, C Geier, Timothy T. Lu
Publikováno v:
Journal of Crohn's and Colitis. 14:S382-S383
Background Inflammatory bowel disease (IBD) is characterised by gut dysbiosis, weakened epithelial barrier, and a dysregulated immune system. Interleukin-22 (IL-22), an IL-10 family cytokine, has demonstrated efficacy in animal IBD models by promotin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35aeecbfeb615bfef694790462826474
https://doi.org/10.1093/ecco-jcc/jjz203.549
https://doi.org/10.1093/ecco-jcc/jjz203.549
Autor:
E Casavant, K T Park, Veronica G. Anania, Jacqueline McBride, W R Mathews, Brandon Harder, Annemarie Lekkerkerker
Publikováno v:
Journal of Crohn's and Colitis. 15:S160-S160
Background Inflammatory bowel disease (IBD) is a multifactorial disorder characterized by chronic gastrointestinal (GI) inflammation. In clinical practice, physicians urgently need biomarkers to monitor changes in mucosal disease to manage treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08a1336662feb4c5790d160f8ed884cf
https://doi.org/10.1093/ecco-jcc/jjab076.181
https://doi.org/10.1093/ecco-jcc/jjab076.181
Autor:
Ajit Dash, John C. Mansfield, Timothy T. Lu, Chloe Li, Annemarie Lekkerkerker, Christian Geier, Yehong Wang, Frank Wagner
Publikováno v:
Gastroenterology. 158:S-1192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40247bb5784431dd6764344f0b5a78c7
https://doi.org/10.1016/s0016-5085(20)33648-9
https://doi.org/10.1016/s0016-5085(20)33648-9
Autor:
Shelly Zhong, Xiaoting Wang, Dimitry M. Danilenko, Ann Herman, Eric Stefanich, Jeff Lutman, Julie Rae, Donna W. Lee, Siddharth Sukumaran, Wenjun Ouyang, Rama Pai, Brandon Harder, Annemarie Lekkerkerker, Estelle Doudement
Publikováno v:
Pharmacology Research & Perspectives
Although Interleukin‐22 (IL‐22) is produced by various leukocytes, it preferentially targets cells with epithelial origins. IL‐22 exerts essential roles in modulating various tissue epithelial functions, such as innate host defense against extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a9c5b0a3f2d6de400449b3abe1bf77
http://europepmc.org/articles/PMC6238097
http://europepmc.org/articles/PMC6238097
Autor:
Rich Erickson, Ann Herman, Michael E. Rothenberg, Annemarie Lekkerkerker, Timothy T. Lu, Eric Stefanich, Romeo Maciuca, Yehong Wang, Dimitry M. Danilenko
Publikováno v:
Clinical pharmacology and therapeutics. 105(1)
Most treatments for epithelial injury target hematopoietic mechanisms, possibly causing immunosuppression. Interleukin (IL)-22 promotes tissue regeneration, acting directly on epithelial cells. UTTR1147A, a human IL-22Fc (immunoglobulin G (IgG)4) fus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb71fa3a2ad63c5da748ef218bedc19e
https://pubmed.ncbi.nlm.nih.gov/29952004
https://pubmed.ncbi.nlm.nih.gov/29952004
Autor:
Eric Stefanich, Lauri Diehl, Kelly M. Loyet, Annemarie Lekkerkerker, Julie Rae, Ann Herman, Dimitry M. Danilenko, Jeff Lutman, Siddharth Sukumaran, Xiaoting Wang, Donna W. Lee, Wenjun Ouyang
Publikováno v:
Biochemical pharmacology. 152
Interleukin (IL)-22 plays protective roles in infections and in inflammatory diseases that have been linked to its meditation of innate immunity via multiple mechanisms. IL-22 binds specifically to its heterodimeric receptor, which is expressed on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825ec8a3828657de6645f481a3ee2c3a
https://pubmed.ncbi.nlm.nih.gov/29608910
https://pubmed.ncbi.nlm.nih.gov/29608910
Autor:
William A. Faubion, Ma Somsouk, Monika Deswal, Deepti Nagarkar, Timothy T. Lu, Kelly M. Loyet, Mary E. Keir, Luz D. Orozco, Rich Erickson, Brandon Harder, Annemarie Lekkerkerker, Nandhini Ramamoorthi
Publikováno v:
Gastroenterology. 152:S965
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddf76fa3865be7bfcb0199de337e12f4
https://doi.org/10.1016/s0016-5085(17)33275-4
https://doi.org/10.1016/s0016-5085(17)33275-4
Autor:
Brandon Harder, M. Choi, Rui Zhao, Ann Herman, A. Noyes, Dimitry M. Danilenko, Julie Rae, Timothy T. Lu, Annemarie Lekkerkerker, A. Polihrom, P. Kulkarni, D. Fillos, Eric Stefanich
Publikováno v:
Journal of Crohn's and Colitis. 11:S289-S289
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0613832f05607be180ccb21b5ec13b19
https://doi.org/10.1093/ecco-jcc/jjx002.543
https://doi.org/10.1093/ecco-jcc/jjx002.543