Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Annemarie Dunger"'
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 93:267-271
DNA synthesis, measured as 3H-thymidine incorporation, was estimated in islets obtained from BB rats before the onset of diabetes and compared with the replication rate of islets obtained from age-matched BB rats having never developed hyperglycaemia
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 99:34-38
We investigated the effect of different sera, as newborn calf serum, fetal calf serum, rat serum and human serum at various concentrations on biofunctions of cultured pancreatic islets. Islets isolated from newborn LEW. 1 W rats were maintained at 37
Autor:
U Fischer, C. Salzsieder, Annemarie Dunger, J. Bahr, Petra Augstein, E. Salzsieder, R. Kubernath, R. Rettig, Peter Heinke
Publikováno v:
Biochemical and Biophysical Research Communications. 290:443-451
The appearance of Fas receptor at the surface of pancreatic beta-cells affected by progressive insulitis strongly suggests that Fas-mediated beta-cell apoptosis plays an important role in the pathogenesis of type 1 diabetes. In support of this concep
Autor:
James M Cunningham, Irene C. Green, Annemarie Dunger, C. A. Delaney, Michael H.L. Green, M. A. Di Matteo
Publikováno v:
Biochemical Pharmacology. 50:2015-2020
We have studied inhibition of glucose-stimulated insulin secretion in islets of Langerhans isolated from adult Sprague-Dawley rats and treated with different alkylating agents. Streptozotocin (STZ), N-methyl-N-nitrosourea (MNU), and N-ethyl-N-nitroso
Publikováno v:
Diabetologie und Stoffwechsel. 4
Publikováno v:
Transplantation. 49:686-689
3H-thymidine incorporation into DNA (estimated as the autoradiographic labeling index [LI]) was used as an index of DNA replication in syngeneic mouse islets grafted into the kidney or liver 4 weeks before unilateral nephrectomy (UN) or partial hepat
Publikováno v:
Diabetologie und Stoffwechsel. 2
Publikováno v:
Autoimmunity. 35(6)
Protective and/or repair mechanisms are thought to be activated in pancreatic beta cells in response to injury during insulitis. Manifestation of type-1 diabetes may depend on an imbalance between beta cell damage and repair. To prove this hypothesis
Autor:
N. John, S. Berg, Irene C. Green, Michael H.L. Green, Moira Harrison, Annemarie Dunger, Jon G. Mabley
Publikováno v:
FEBS letters. 435(2-3)
Treatment of neonatal rat islets of Langerhans with combined cytokines (interleukin-1beta 10(-10) M, tumour necrosis factor-alpha 10(-10) M, interferon-gamma 5 U/ml) led to extensive cell death, which was potentiated by Fas activation with the anti-F
Publikováno v:
Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 105
The aim of this study was to compare the effect of long-term diabetes with that of a long-term high protein diet in vivo on the kidney function and in vitro on cellular parameters of isolated glomeruli of BB rats. Four groups of rats were investigate