G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis

Autor: Annemarie Boleij, Payam Fathi, William Dalton, Ben Park, Xinqun Wu, David Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. Mackenzie, Laura Jenkins, Graeme. Milligan, Shaoguang Wu, Cynthia L. Sears

Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)

Boleij et al. show that G protein-coupled receptor 35 (GPR35) regulates the responses to enterotoxigenic Bacteroides fragilis (ETBF) in colonic epithelial cells. They find that GPR35-deficiency nearly protected mice from ETBF-induced death, suggestin

Externí odkaz: https://doaj.org/article/2986eba9551643dc8608d3a4c5b5b496

Correction: Protocol of the Healthy Brain Study: An accessible resource for understanding the human brain and how it dynamically and individually operates in its bio-social context.

Autor: Healthy Brain Study consortium, Esther Aarts, Agnes Akkerman, Mareike Altgassen, Ronald Bartels, Debby Beckers, Kirsten Bevelander, Erik Bijleveld, Esmeralda Blaney Davidson, Annemarie Boleij, Janita Bralten, Toon Cillessen, Jurgen Claassen, Roshan Cools, Ineke Cornelissen, Martin Dresler, Thijs Eijsvogels, Myrthe Faber, Guillén Fernández, Bernd Figner, Matthias Fritsche, Sascha Füllbrunn, Surya Gayet, Marleen M H J van Gelder, Marcel van Gerven, Sabine Geurts, Corina U Greven, Martine Groefsema, Koen Haak, Peter Hagoort, Yvonne Hartman, Beatrice van der Heijden, Erno Hermans, Vivian Heuvelmans, Florian Hintz, Janet den Hollander, Anneloes M Hulsman, Sebastian Idesis, Martin Jaeger, Esther Janse, Joost Janzing, Roy P C Kessels, Johan C Karremans, Willemien de Kleijn, Marieke Klein, Floris Klumpers, Nils Kohn, Hubert Korzilius, Bas Krahmer, Floris de Lange, Judith van Leeuwen, Huaiyu Liu, Maartje Luijten, Peggy Manders, Katerina Manevska, José P Marques, Jon Matthews, James M McQueen, Pieter Medendorp, René Melis, Antje Meyer, Joukje Oosterman, Lucy Overbeek, Marius Peelen, Jean Popma, Geert Postma, Karin Roelofs, Yvonne G T van Rossenberg, Gabi Schaap, Paul Scheepers, Luc Selen, Marianne Starren, Dorine W Swinkels, Indira Tendolkar, Dick Thijssen, Hans Timmerman, Rayyan Tutunji, Anil Tuladhar, Harm Veling, Maaike Verhagen, Jasper Verkroost, Jacqueline Vink, Vivian Vriezekolk, Janna Vrijsen, Jana Vyrastekova, Selina van der Wal, Roel Willems, Arthur Willemsen

Publikováno v: PLoS ONE, Vol 17, Iss 4, p e0267071 (2022)

[This corrects the article DOI: 10.1371/journal.pone.0260952.].

Externí odkaz: https://doaj.org/article/da5c348b79064f2baeef684ed0f5ebca

Mechanisms of Immune Checkpoint Inhibitor-Mediated Colitis

Autor: Harm Westdorp, Mark W. D. Sweep, Mark A. J. Gorris, Frank Hoentjen, Marye J. Boers-Sonderen, Rachel S. van der Post, Michel M. van den Heuvel, Berber Piet, Annemarie Boleij, Haiko J. Bloemendal, I. Jolanda M. de Vries

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Immune checkpoint inhibitors (ICIs) have provided tremendous clinical benefit in several cancer types. However, systemic activation of the immune system also leads to several immune-related adverse events. Of these, ICI-mediated colitis (IMC) occurs

Externí odkaz: https://doaj.org/article/3d7a2cc22242488098febabeb1c8b7f3

Higher Prevalence of Bacteroides fragilis in Crohn’s Disease Exacerbations and Strain-Dependent Increase of Epithelial Resistance

Autor: Heike E. F. Becker, Casper Jamin, Liene Bervoets, Annemarie Boleij, Pan Xu, Marie J. Pierik, Frank R. M. Stassen, Paul H. M. Savelkoul, John Penders, Daisy M. A. E. Jonkers

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)

Bacteroides fragilis has previously been linked to Crohn’s disease (CD) exacerbations, but results are inconsistent and underlying mechanisms unknown. This study investigates the epidemiology of B. fragilis and its virulence factors bft (enterotoxi

Externí odkaz: https://doaj.org/article/4fd524289db14af5b3284d0bc9de6988

Protocol of the Healthy Brain Study: An accessible resource for understanding the human brain and how it dynamically and individually operates in its bio-social context.

Autor: Healthy Brain Study consortium, Esther Aarts, Agnes Akkerman, Mareike Altgassen, Ronald Bartels, Becky Beckers, Kirsten Bevelander, Erik Bijleveld, Esmeralda Blaney Davidson, Annemarie Boleij, Janita Bralten, Toon Cillessen, Jurgen Claassen, Roshan Cools, Ineke Cornelissen, Martin Dresler, Thijs Eijsvogels, Myrthe Faber, Guillén Fernández, Bernd Figner, Matthias Fritsche, Sascha Füllbrunn, Surya Gayet, Marleen M. H. J. van Gelder, Marcel van Gerven, Sabine Geurts, Corina U. Greven, Martine Groefsema, Koen Haak, Peter Hagoort, Yvonne Hartman, Beatrice van der Heijden, Erno Hermans, Vivian Heuvelmans, Florian Hintz, Janet den Hollander, Anneloes M. Hulsman, Sebastian Idesis, Martin Jaeger, Esther Janse, Joost Janzing, Roy P. C. Kessels, Johan C. Karremans, Willemien de Kleijn, Marieke Klein, Floris Klumpers, Nils Kohn, Hubert Korzilius, Bas Krahmer, Floris de Lange, Judith van Leeuwen, Huaiyu Liu, Maartje Luijten, Peggy Manders, Katerina Manevska, José P. Marques, Jon Matthews, James M. McQueen, Pieter Medendorp, René Melis, Antje Meyer, Joukje Oosterman, Lucy Overbeek, Marius Peelen, Jean Popma, Geert Postma, Karin Roelofs, Yvonne G. T. van Rossenberg, Gabi Schaap, Paul Scheepers, Luc Selen, Marianne Starren, Dorine W. Swinkels, Indira Tendolkar, Dick Thijssen, Hans Timmerman, Rayyan Tutunji, Anil Tuladhar, Harm Veling, Maaike Verhagen, Jasper Verkroost, Jacqueline Vink, Vivian Vriezekolk, Janna Vrijsen, Jana Vyrastekova, Selina van der Wal, Roel Willems, Arthur Willemsen

Publikováno v: PLoS ONE, Vol 16, Iss 12, p e0260952 (2021)

The endeavor to understand the human brain has seen more progress in the last few decades than in the previous two millennia. Still, our understanding of how the human brain relates to behavior in the real world and how this link is modulated by biol

Externí odkaz: https://doaj.org/article/04de1a72094f444d9af76cbbcdbb5ec2