Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Annelise M. Cassidy"'
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12630- (2022)
Despite tremendous advances in genome editing technologies, generation of conditional alleles in mice has remained challenging. Recent studies in cells have successfully made use of short artificial introns to engineer conditional alleles. The approa
Externí odkaz:
https://doaj.org/article/c0ae5083c633440f9abcca0294b08ba1
Dissecting protein function in vivo: Engineering allelic series in mice using CRISPR-Cas9 technology
Publikováno v:
Methods in enzymology. 667
Allelic series are extremely valuable genetic tools to study gene function and identify essential structural features of gene products. In mice, allelic series have been engineered using conventional gene targeting in embryonic stem cells or chemical
Dissecting protein function in vivo: Engineering allelic series in mice using CRISPR-Cas9 technology
Publikováno v:
Methods in Enzymology ISBN: 9780323915410
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51da2e27e8e0a97e69d6e3e63172fded
https://doi.org/10.1016/bs.mie.2022.03.053
https://doi.org/10.1016/bs.mie.2022.03.053