Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Anneline Pinson"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Malformations of the human neocortex in development constitute a heterogeneous group of complex disorders, resulting in pathologies such as intellectual disability and abnormal neurological/psychiatric conditions such as epilepsy or autism. Advances
Externí odkaz:
https://doaj.org/article/0b15f93362ba4daea312adc30d369129
Autor:
Marta Florio, Michael Heide, Anneline Pinson, Holger Brandl, Mareike Albert, Sylke Winkler, Pauline Wimberger, Wieland B Huttner, Michael Hiller
Publikováno v:
eLife, Vol 7 (2018)
Understanding the molecular basis that underlies the expansion of the neocortex during primate, and notably human, evolution requires the identification of genes that are particularly active in the neural stem and progenitor cells of the developing n
Externí odkaz:
https://doaj.org/article/58561a925a8e40d9807f929452a6d5d7
Autor:
Elise Naveau, Anneline Pinson, Arlette Gérard, Laurent Nguyen, Corinne Charlier, Jean-Pierre Thomé, R Thomas Zoeller, Jean-Pierre Bourguignon, Anne-Simone Parent
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91903 (2014)
Polychlorinated biphenyls (PCBs) are environmental contaminants that persist in environment and human tissues. Perinatal exposure to these endocrine disruptors causes cognitive deficits and learning disabilities in children. These effects may involve
Externí odkaz:
https://doaj.org/article/e61cfe0a55af41fca19449ec70e3f260
Publikováno v:
Science. 379
Heraiet al. discuss the known fact that a low percentage of modern humans who lack any overt phenotypes carry the ancestralTKTL1allele. Our paper demonstrates that the amino acid substitution in TKTL1 increases neural progenitor cells and neurogenesi
Autor:
Anneline Pinson, Elena Sevrin, Christina Chatzi, Benjamin Le Gac, Marc Thiry, Gary L. Westbrook, Anne-Simone Parent
Publikováno v:
Neuroendocrinology.
Introduction: Hippocampal newborn neurons integrate into functional circuits where they play an important role in learning and memory. We previously showed that perinatal exposure to Aroclor 1254, a commercial mixture of polychlorinated biphenyls (PC
Autor:
Anneline Pinson, Lei Xing, Takashi Namba, Nereo Kalebic, Jula Peters, Christina Eugster Oegema, Sofia Traikov, Katrin Reppe, Stephan Riesenberg, Tomislav Maricic, Razvan Derihaci, Pauline Wimberger, Svante Pääbo, Wieland B. Huttner
Publikováno v:
Science. 377
Neanderthal brains were similar in size to those of modern humans. We sought to investigate potential differences in neurogenesis during neocortex development. Modern human transketolase-like 1 (TKTL1) differs from Neanderthal TKTL1 by a lysine-to-ar
Autor:
Michaela Wilsch-Bräuninger, Kaiqing Zhang, Jessica Herbst, Wieland B. Huttner, Christof Niehrs, Andreas Schedl, Edoardo Fatti, Fabio Da Silva, Valerie Vidal, Anneline Pinson
Publikováno v:
The EMBO Journal
The EMBO Journal, 40 (19)
The EMBO Journal, 40 (19)
The role of WNT/β-catenin signalling in mouse neocortex development remains ambiguous. Most studies demonstrate that WNT/β-catenin regulates progenitor self-renewal but others suggest it can also promote differentiation. Here we explore the role of
Autor:
Radislav Sedlacek, Agnieszka Kubik-Zahorodna, Anneline Pinson, Takashi Namba, Mihail Sarov, Marta Florio, Wieland B. Huttner, Lei Xing, Jan Prochazka
Publikováno v:
The EMBO Journal
Neocortex expansion during human evolution provides a basis for our enhanced cognitive abilities. Yet, which genes implicated in neocortex expansion are actually responsible for higher cognitive abilities is unknown. The expression of human‐specifi
Autor:
Wieland B. Huttner, Anneline Pinson
Publikováno v:
Current opinion in cell biology. 73
The evolutionary expansion of the neocortex, the seat of higher cognitive functions in humans, is primarily due to an increased and prolonged proliferation of neural progenitor cells during development. Basal progenitors, and in particular basal radi
Autor:
Arlette Gerard, Delphine Franssen, Anneline Pinson, Jean-Pierre Bourguignon, Anne-Simone Parent
Publikováno v:
Comptes Rendus Biologies. 340:432-438
Endocrine disruption is commonly thought to be restricted to a direct endocrine mode of action i.e. the perturbation of the activation of a given type of hormonal receptor by its natural ligand. Consistent with the WHO definition of an endocrine disr