Výsledky vyhledávání - "Anneli Strömberg"

Akademický článek

Activated Peyer′s patch B cells sample antigen directly from M cells in the subepithelial dome

Autor: Rathan Joy Komban, Anneli Strömberg, Adi Biram, Jakob Cervin, Cristina Lebrero-Fernández, Neil Mabbott, Ulf Yrlid, Ziv Shulman, Mats Bemark, Nils Lycke

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Gut lumen antigens must be continuously sampled by the immune system to maintain proper immune homeostasis. Here the authors show that activated CCR6+CCR1+GL7- gut B cells retrieve lumen antigens from specialized M cells and transfer them across the

Externí odkaz: https://doaj.org/article/dfa3b986a6dc4e698df2c098d4517404

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Akademický článek

Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization

Autor: Mats Bemark, Helena Hazanov, Anneli Strömberg, Rathan Komban, Joel Holmqvist, Sofia Köster, Johan Mattsson, Per Sikora, Ramit Mehr, Nils Y. Lycke

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)

The presence of long-lived memory IgA-producing B cells in the intestine has been difficult to document. Here the authors show that these cells can be induced by oral but not systemic immunization in mice, and characterize unique features that distin

Externí odkaz: https://doaj.org/article/3f378a82abe14213ae3c6b066e47eba1

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Peyer’s patch TH17 cells are dispensable for gut IgA responses to oral immunization

Autor: Inta Gribonika, Anneli Strömberg, Cristina Lebrero-Fernandez, Karin Schön, James Moon, Mats Bemark, Nils Lycke

Publikováno v: Science Immunology. 7

T helper 17 (TH17) cells located at the Peyer’s patch (PP) inductive site and at the lamina propria effector site of the intestinal immune system are responsive to both pathogenic and commensal bacteria. Their plasticity to convert into follicular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e7354e8426d01d9ba8e47bc9b1b43f3
https://doi.org/10.1126/sciimmunol.abc5500

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The CTA1-DD adjuvant strongly potentiates follicular dendritic cell function and germinal center formation, which results in improved neonatal immunization

Autor: Johan Mattsson, Valentina Bernasconi, Karin Schön, Anneli Strömberg, Nils Lycke, Sophie Schussek, Inta Gribonika, Ulf Alexander Wenzel

Publikováno v: Mucosal Immunology

Vaccination of neonates and young infants is hampered by the relative immaturity of their immune systems and the lack of safe and efficacious vaccine adjuvants. Immaturity of the follicular dendritic cells (FDCs), in particular, appears to play a cri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22ac4ba1bf9179b055f526d18a686d9
http://europepmc.org/articles/PMC7223721

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ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection

Autor: Mohammad Arabpour, Cristina Lebrero-Fernandez, Karin Schön, Anneli Strömberg, Vanja Börjesson, Katharina Lahl, Marlies Ballegeer, Xavier Saelens, Davide Angeletti, William Agace, Nils Lycke

Publikováno v: MUCOSAL IMMUNOLOGY
Arabpour, M, Lebrero-Fernandez, C, Schön, K, Strömberg, A, Börjesson, V, Lahl, K, Ballegeer, M, Saelens, X, Angeletti, D, Agace, W & Lycke, N 2022, ' ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection ', Mucosal Immunology, vol. 15, pp. 745-761 . https://doi.org/10.1038/s41385-022-00510-1

Migratory dendritic cells expressing CD103 are the targets for mucosal vaccines. These belong to either of two lineage-restricted subsets, cDC1 or cDC2 cells, which have been linked to priming of functionally distinct CD4 T cells. However, recent stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a136d9d22b39270548d7e25c49038fde
https://pubmed.ncbi.nlm.nih.gov/35418673

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ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 development and protection against influenza virus infection

Autor: Karin Schön, Mohammad Arabpour, Katherina Lahl, Vanja Börjesson, Davide Angeletti, Anneli Strömberg, Nils Lycke, Cristina Lebrero-Fernández, William Agace

Migratory dendritic cells carrying CD103 are the targets for mucosal vaccines. These belong to either of two lineage restricted subsets, cDC1 or cDC2 cells, which have been linked to priming of functionally distinct CD4 T cells. However, recent studi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b28c0f2bf2bb8e9536781d7e39a2280
https://doi.org/10.21203/rs.3.rs-801483/v1

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Clonotypic analysis of protective influenza M2e-specific lung resident Th17 memory cells reveals extensive functional diversity

Autor: Ajibola Omokanye, Li Ching Ong, Cristina Lebrero-Fernandez, Valentina Bernasconi, Karin Schön, Anneli Strömberg, Mats Bemark, Xavier Saelens, Paulo Czarnewski, Nils Lycke

Publikováno v: MUCOSAL IMMUNOLOGY

The fate of tissue-resident memory CD4 T cells (Trm) has been incompletely investigated. Here we show that intranasal, but not parenteral, immunization with CTA1-3M2e-DD stimulated M2e-specific Th17 Trm cells, which conferred strong protection agains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87fbfb6ceb210cb0c22451f3c9a6a6cc
https://pubmed.ncbi.nlm.nih.gov/35260804

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Class-switch recombination to IgA in the Peyer's patches requires natural thymus-derived Tregs and appears to be antigen independent

Autor: Inta, Gribonika, Dubravka Grdic, Eliasson, Rakesh K, Chandode, Karin, Schön, Anneli, Strömberg, Mats, Bemark, Nils Y, Lycke

Publikováno v: Mucosal immunology. 12(6)

Our understanding of how class-switch recombination (CSR) to IgA occurs in the gut is still incomplete. Earlier studies have indicated that Tregs are important for IgA CSR and these cells were thought to transform into follicular helper T cells (Tfh)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::001ca68f69b73fd98748e891821032b7
https://pubmed.ncbi.nlm.nih.gov/31501516

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Absence of surrogate light chain results in spontaneous autoreactive germinal centres expanding V(H)81X-expressing B cells

Autor: Ola Grimsholm, Anneli Strömberg, Giljun Park, Ulf Yrlid, Weicheng Ren, Haixia Chen, Susanna Cardell, Dongfeng Chen, Nina Höök, Alessandra De Riva, Angelina I. Bernardi, Inga-Lill Mårtensson, Berglind Bergmann, Sofia Andersson, Alessandro Camponeschi, Inger Gjertsson

Publikováno v: Nature communications. 6

Random recombination of antibody heavy- and light-chain genes results in a diverse B-cell receptor (BCR) repertoire including self-reactive BCRs. However, tolerance mechanisms that prevent the development of self-reactive B cells remain incompletely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8118020d4ebf04479a11c74ee36d4892
https://pubmed.ncbi.nlm.nih.gov/25959489

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