Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anneke N. Werk"'
Autor:
Muhammad Kashif Nisar, H. R. Ahmad, Ingolf Cascorbi, Nasir Ali Afsar, Henrike Bruckmueller, Anneke N. Werk
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Genetic polymorphism of drug metabolizing enzymes and transporters may influence drug response. The frequency varies substantially between ethnicities thus having implications on appropriate selection and dosage of various drugs in different populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957560e887944d83315542e16fa2e466
http://link.springer.com/article/10.1038/s41598-019-43736-z
http://link.springer.com/article/10.1038/s41598-019-43736-z
Autor:
Martin Tepel, Lutz Renders, Amke Caliebe, Anneke N. Werk, Thorsten Feldkamp, Henrike Bruckmueller, Ulrich Kunzendorf, Ingolf Cascorbi, Christoffer Borst
Publikováno v:
ResearcherID
Bruckmueller, H, Werk, A N, Renders, L, Feldkamp, T, Tepel, M, Borst, C, Caliebe, A, Kunzendorf, U & Cascorbi, I 2015, ' Which genetic determinants should be considered for tacrolimus dose optimization in kidney transplantation? A combined analysis of genes affecting the CYP3A locus ', Therapeutic Drug Monitoring, vol. 37, no. 3, pp. 288-295 . https://doi.org/10.1097/FTD.0000000000000142
Bruckmueller, H, Werk, A N, Renders, L, Feldkamp, T, Tepel, M, Borst, C, Caliebe, A, Kunzendorf, U & Cascorbi, I 2015, ' Which genetic determinants should be considered for tacrolimus dose optimization in kidney transplantation? A combined analysis of genes affecting the CYP3A locus ', Therapeutic Drug Monitoring, vol. 37, no. 3, pp. 288-295 . https://doi.org/10.1097/FTD.0000000000000142
Background: Tacrolimus is established as immunosuppressant after kidney transplantation. Polymorphism of the cytochrome P450 3A5 (CYP3A5) gene contributes significantly to tacrolimus dose requirements. Recently, CYP3A4*22 was reported to additionally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c36d049781b7795eb107ef3ffb9e1a
https://doi.org/10.1097/ftd.0000000000000142
https://doi.org/10.1097/ftd.0000000000000142
Autor:
Istvan Balogh, Constantinos Deltas, Nada Bozina, Godfrey Grech, Eleni Dalabira, Ľudevít Kádaši, Halyna Makukh, Theodora Katsila, Vytautas Kasiulevičius, Andrew P. Stubbs, Alison Motsinger-Rief, Joseph A. Borg, Clint Mizzi, Sonja Pavlovic, Nduna Dzimiri, Alessio Squassina, María José Torres, Christina Mitropoulou, Branka Zukic, Giuseppe Saglio, Peter J. van der Spek, Nazli Basak, Angel Carracedo, Anneke N. Werk, Maja Stojiljkovic, Ingolf Cascorbi, Konstantinos Voskarides, Ron H.N. van Schaik, Judit Kumuthini, Giuseppe Novelli, Paola Borgiani, Ruwen Böhm, Beata Burzynska, Ming Ta Michael Lee, Elza Khusnutdinova, Ioanna Papantoni, Yiannis L. Loukas, Maria Del Zompo, Henrike Bruckmueller, Salma M. Wakil, Howard L. Mc Leod, Vaidutis Kučinskas, Marek Turnovec, George P. Patrinos, Ron H.J. Mathijssen, Vita Dolzan, Milan Macek, Konstantinos Mitropoulos, Anthony G. Fenech, Jadranka Sertić
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0172595 (2017)
PLoS ONE, Vol 12, Iss 2, p e0172595 (2017)
This publication is a correction of the thirty-third author’s name. The URL of the article is: https://www.um.edu.mt/library/oar/handle/123456789/25240
peer-reviewed
peer-reviewed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8d756683c0cd6ce0389b2d3c02348a
http://europepmc.org/articles/PMC5313168
http://europepmc.org/articles/PMC5313168
Publikováno v:
British Journal of Clinical Pharmacology. 77:587-596
MicroRNAs (miRNAs) are small noncoding RNAs, which regulate the expression of their target genes post-transcriptionally by RNA interference. They are involved in almost all cellular processes, including proliferation, differentiation, apoptosis, cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee62c16684791b75a8531c28360b5231
https://doi.org/10.1111/bcp.12251
https://doi.org/10.1111/bcp.12251
Autor:
J H Bräsen, Christoph Schmaderer, Marcel Roos, Uwe Heemann, Andre Franke, Dominik Steubl, Ingolf Cascorbi, Lutz Renders, Anneke N. Werk, Georg Hemmrich-Stanisak, S. Lefeldt, Claudius Küchle, Henrike Bruckmueller
Publikováno v:
Clinical Pharmacology & Therapeutics. 95:416-422
Cytochrome P450 3A4 (CYP3A4) is a major drug-metabolizing enzyme that is widely investigated. So far, no homozygous inactive variant has been described. We report on a 19-year-old kidney transplant patient suffering from Alport syndrome, who experien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58531aeb1b9abfdbbf75fa27f34d76f
https://doi.org/10.1038/clpt.2013.210
https://doi.org/10.1038/clpt.2013.210
Publikováno v:
European Journal of Clinical Pharmacology. 69:17-23
The attempt to optimize drug treatment of patients by using evidenced-based medicine considering individual physiological and disease-related conditions is standard of modern medicine. Pharmacogenetics (PGx) has contributed to individualization consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a850b2d975a025f7046d6cd07a19693
https://doi.org/10.1007/s00228-013-1492-x
https://doi.org/10.1007/s00228-013-1492-x
Autor:
Anneke N. Werk, Ingolf Cascorbi
Publikováno v:
Expert opinion on drug metabolismtoxicology. 13(1)
Cancer pharmacogenetics usually considers tumor-specific targets. However, hereditary genetic variants may interfere with the pharmacokinetics of antimetabolites and other anti-cancer drugs, which may lead to severe adverse events. Areas covered: Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95850ce9d9ce6112cfb1f490024443b1
https://pubmed.ncbi.nlm.nih.gov/27603572
https://pubmed.ncbi.nlm.nih.gov/27603572
Publikováno v:
Pharmacogenomics. 13:645-649
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e91258e4f671964af94036e8a122e476
https://doi.org/10.2217/pgs.12.20
https://doi.org/10.2217/pgs.12.20
Autor:
Stephan T. Becker, Alexander Gröbe, Ralf Smeets, Robert Häsler, Jörg Wiltfang, Max Heiland, Benedicta Beck-Broichsitter, Anneke N. Werk, Ingolf Cascorbi
Publikováno v:
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 43(8)
Purpose Although bone tissue engineering techniques have become more and more sophisticated than in the past, natural bone healing mechanisms have not been sufficiently considered for further improvement of these techniques so far. We used an establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088ee7ce19fa038586d66db878e375bb
https://pubmed.ncbi.nlm.nih.gov/26189147
https://pubmed.ncbi.nlm.nih.gov/26189147
Autor:
Anneke N. Werk, Ingolf Cascorbi
Publikováno v:
Pharmacogenomics. 13:997-999
This conference scene outlines a selection of sessions, which deals with the field of pharmacogenomics, held at the 78th Annual meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT), which took place from 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f920b02bea4bb48565061a00b475fb24
https://doi.org/10.2217/pgs.12.66
https://doi.org/10.2217/pgs.12.66