Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe

Autor: Anneke Hibbel, Aliona Bogdanova, Mohammed Mahamdeh, Anita Jannasch, Marko Storch, Erik Schäffer, Dimitris Liakopoulos, Jonathon Howard

Publikováno v: eLife, Vol 4 (2015)

The size and position of mitotic spindles is determined by the lengths of their constituent microtubules. Regulation of microtubule length requires feedback to set the balance between growth and shrinkage. Whereas negative feedback mechanisms for mic

Externí odkaz: https://doaj.org/article/ba4c6ae3190241f79a1e98a283b088f4

CLASP stabilizes microtubule plus ends created by serving to drive cortical array reorientation

Autor: Marco Saltini, Anne Mie C. Emons, David W. Ehrhardt, Jelmer J. Lindeboom, Masayoshi Nakamura, Tijs Keetlaar, Bela M. Mulder, Ankit Walia, Viktor Kirik, Anneke Hibbel, John C. Sedbrook

Central to building and reorganizing cytoskeletal arrays is the creation of new polymers. While nucleation has been the major focus of study for new microtubule generation, severing has been proposed as an alternative mechanism to create new polymers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36f83f3f989e71ad1822ab72e632c87
https://doi.org/10.1101/196329

Challenging the cholinergic system in mild cognitive impairment: a pharmacological fMRI study

Autor: Frederik Barkhof, Philip Scheltens, Dirk L. Knol, Luc Truyen, Rutger Goekoop, Serge A.R.B. Rombouts, Anneke Hibbel, Cees Jonker

Publikováno v: Goekoop, R, Rombouts, S A R B, Jonker, C, Hibbel, A, Knol, D L, Truyen, L, Barkhof, F & Scheltens, P 2004, ' Challenging the cholinergic system in mild cognitive impairment : A pharmacological fMRI study ', NeuroImage, vol. 23, no. 4, pp. 1450-1459 . https://doi.org/10.1016/j.neuroimage.2004.08.006
NeuroImage, 23(4), 1450-1459. Academic Press Inc.

Mild cognitive impairment (MCI) often represents an early form of Alzheimer disease (AD). In both MCI and AD, characteristic cholinergic changes may occur. Functional magnetic resonance imaging (fMRI) may help to examine neurochemical changes in earl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae4372468290f0d5042ba26e6f0c806
https://doi.org/10.1016/j.neuroimage.2004.08.006

P2-222 A comparison of whole-brain activation during face encoding between healthy aging, mild cognitive impairment and Alzheimer's disease

Autor: Frederik Barkhof, Serge A.R.B. Rombouts, Anneke Hibbel, Philip Scheltens, Rutger Goekoop

Publikováno v: Neurobiology of Aging. 25:S294

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2e35a3b6fe8cee41828eb4c63eaef6c
https://doi.org/10.1016/s0197-4580(04)80968-0