Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Annegret Nath"'
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88887 (2014)
In actively dividing eukaryotic cells, chromosome ends (telomeres) are subject to progressive shortening, unless they are maintained by the action of telomerase, a dedicated enzyme that adds DNA sequence repeats to chromosomal 3'end. For its enzymati
Externí odkaz:
https://doaj.org/article/ec68d5d4f7d44e4b9a355595c1f88483
Autor:
Sarah Wälde, Ralph H. Kehlenbach, Ulrich Rothbauer, Annegret Nath, Ketan Thakar, Saskia Hutten, Christiane Spillner, Stefan Wiemann
Publikováno v:
Traffic. 13:218-233
In vertebrates, the nuclear pore complex (NPC), the gate for transport of macromolecules between the nucleus and the cytoplasm, consists of approximately 30 different nucleoporins (Nups). The Nup and SUMO E3-ligase Nup358/RanBP2 are the major compone
Publikováno v:
Journal of Biological Chemistry. 281:20883-20890
The Rev protein of human immunodeficiency virus type 1 is an RNA-binding protein that is required for nuclear export of unspliced and partially spliced viral mRNAs. Nuclear import of human immunodeficiency virus type 1 Rev has been suggested to depen
Publikováno v:
Journal of Biological Chemistry. 281:5492-5499
c-Fos, a component of the transcription factor AP-1, is rapidly imported into the nucleus after translation. We established an in vitro system using digitonin-permeabilized cells to analyze nuclear import of c-Fos in detail. Two import receptors of t
Publikováno v:
Journal of Biological Chemistry. 272:20222-20229
In cultured rat hepatocytes the degradation of phosphoenolpyruvate carboxykinase mRNA might be regulated by protein(s), which by binding to the mRNA alter its stability. The 3′-untranslated region of phosphoenolpyruvate carboxykinase mRNA as a pote
Publikováno v:
Hepatology. 26:73-80
In cultured rat hepatocytes, the gluconeogenic key enzyme, phosphoenolpyruvate carboxykinase (PCK), is induced by glucagon via elevation of cyclic 3',5' adenosine monophosphate (cAMP). The proinflammatory cytokine, interleukin-6 (IL-6), which in the
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e88887 (2014)
PLoS ONE, Vol 9, Iss 2, p e88887 (2014)
n actively dividing eukaryotic cells, chromosome ends (telomeres) are subject to progressive shortening, unless they are maintained by the action of telomerase, a dedicated enzyme that adds DNA sequence repeats to chromosomal 3′end. For its enzymat
Autor:
Desmond J. Fitzgerald, Simone Marcone, Tina Lampe, Annegret Nath, Christiane Spillner, Ralph H. Kehlenbach, Cornelia Frohnert, Mark Hilliard
The signaling molecule 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) has been described as the "anti-inflammatory prostaglandin." Here we show that substrates of the nuclear export receptor CRM1 accumulate in the nucleus in the presence of 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20757d60601e19ebd389bdbbfbf5455c
https://europepmc.org/articles/PMC2903415/
https://europepmc.org/articles/PMC2903415/
Publikováno v:
The Journal of biological chemistry. 281(9)
c-Fos, a component of the transcription factor AP-1, is rapidly imported into the nucleus after translation. We established an in vitro system using digitonin-permeabilized cells to analyze nuclear import of c-Fos in detail. Two import receptors of t
Publikováno v:
Biochemical pharmacology. 66(4)
Prostanoids, i.e. prostaglandins and thromboxane, regulate liver-specific functions both in homeostasis and during defense reactions. For example, prostanoids are released from Kupffer cells, the resident liver macrophages, in response to the inflamm