Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Annege Vledder"'
Autor:
Anneke L. Eerkens, Koen Brummel, Annegé Vledder, Sterre T. Paijens, Marta Requesens, Dominik Loiero, Nienke van Rooij, Annechien Plat, Floris-Jan Haan, Patty Klok, Refika Yigit, Thijs Roelofsen, Natascha M. de Lange, Rie Klomp, David Church, Arja ter Elst, René Wardenaar, Diana Spierings, Floris Foijer, Viktor Hendrik Koelzer, Tjalling Bosse, Joost Bart, Mathilde Jalving, Anna K. L. Reyners, Marco de Bruyn, Hans W. Nijman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Neoadjuvant immune checkpoint blockade (ICB) has shown unprecedented activity in mismatch repair deficient (MMRd) colorectal cancers, but its effectiveness in MMRd endometrial cancer (EC) remains unknown. In this investigator-driven, phase I
Externí odkaz:
https://doaj.org/article/1b7aedf643dd44ed914769ada0de8d61
Autor:
Marco de Bruyn, Hans Nijman, Annegé Vledder, Jeroen Rovers, Hester Van Zeeburg, Satwinder Singh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/fd68770e93ee4da4be4259e459440a3b
Publikováno v:
Cell Mol Immunol
The clinical success of cancer immune checkpoint blockade (ICB) has refocused attention on tumor-infiltrating lymphocytes (TILs) across cancer types. The outcome of immune checkpoint inhibitor therapy in cancer patients has been linked to the quality
Rapid and efficient generation of antigen-specific isogenic T cells from cryopreserved blood samples
Publikováno v:
Immunology and Cell Biology. Wiley
ObjectivesCRISPR/Cas9-mediated gene editing has been leveraged for the modification of human and mouse T cells. However, limited experience is available on the application of CRISPR/Cas9 electroporation in cryopreserved T cells collected during e.g.
Autor:
Kyhw Yin, M. de Bruyn, Hans W. Nijman, Sharat Singh, Haoxiao Zuo, M Nagasawa, Annege Vledder, S Tabruyn, M.-J. van Lierop, Erik Manting, Remco Bos
Publikováno v:
Ovarian cancer.
Introduction/Background* Ovarian cancer (OC) causes high mortality due to late diagnosis and high rate of relapse following initial therapy. Immunotherapy in combination with standard treatment modalities forms a promising new treatment approach. DCP
Autor:
N.M. de Lange, Hagma H. Workel, Joost Bart, M. de Bruyn, Evelien W. Duiker, Annege Vledder, A. J. Kruse, Harmen Hollema, R. Yigit, Annechien Plat, S. T. Paijens, D Loiero, V. H. Koelzer, H.J.G. Arts, Hans W. Nijman, A. M. Hendriks, Mathilde Jalving, Gba Wisman, N Werner
Publikováno v:
Ovarian cancer.
Introduction/Background* CD103-positive tissue resident memory-like CD8+ T cells (CD8CD103 TRM) are associated with improved prognosis across malignancies, including high-grade serous ovarian cancer (HGSOC). We investigated whether quantification of
Autor:
R. Yigit, Hagma H. Workel, S. T. Paijens, A. J. Kruse, Joost Bart, D Loiero, M. de Bruyn, Annege Vledder, N.M. de Lange, Annechien Plat, Mathilde Jalving, G. B. A. Wisman, V. H. Koelzer, H.J.G. Arts, N Werner, Harmen Hollema, Evelien W. Duiker, Hans W. Nijman, A. M. Hendriks
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, 10(1):1935104. Taylor & Francis Group
Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, 10(1):1935104. Taylor & Francis Group
CD103-positive tissue resident memory-like CD8+ T cells (CD8CD103 TRM) are associated with improved prognosis across malignancies, including high-grade serous ovarian cancer (HGSOC). However, whether quantification of CD8, CD103 or both is required t
Autor:
Marijke M. Faas, Tom E.C. Kieffer, Annege Vledder, Jelmer R. Prins, Anne Laskewitz, Sicco A. Scherjon
Publikováno v:
American Journal of Reproductive Immunology
American Journal of Reproductive Immunology, 84(4):13293. Wiley
American Journal of Reproductive Immunology, 84(4):13293. Wiley
Problem: Preeclampsia is a major cause of fetal and maternal mortality and morbidity. Disturbed fetal-maternal immune tolerance, and therewith memory T cells, might be involved in its etiology. This study aims to give insight into memory T-cell popul
Publikováno v:
Pregnancy Hypertension. 13:S29-S30
Introduction Previous studies indicate that pregnancy persistently affects memory T lymphocyte populations. However, their function and relevance in fetal-maternal immune tolerance and therewith immune related complications of pregnancy are not known
Autor:
Marijke M. Faas, Lisanne Zijlker, Jelmer R. Prins, Annege Vledder, Anne Laskewitz, Sicco A. Scherjon
Publikováno v:
Pregnancy Hypertension. 13:S97
Introduction During pregnancy, tolerance towards the fetus is induced by adaptations in the maternal immune system. Maladaptation of the maternal immune system is associated with pregnancy complications like preeclampsia and fetal growth restriction.