Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Anne-Sophie Wozny"'
Autor:
Emmanuel Grolleau, Julie Candiracci, Gaelle Lescuyer, David Barthelemy, Nazim Benzerdjeb, Christine Haon, Florence Geiguer, Margaux Raffin, Nathalie Hardat, Julie Balandier, Rémi Rabeuf, Lara Chalabreysse, Anne-Sophie Wozny, Guillaume Rommelaere, Claire Rodriguez-Lafrasse, Fabien Subtil, Sébastien Couraud, Marielle Herzog, Lea Payen-Gay
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1255 (2023)
The molecular profiling of circulating tumor DNA (ctDNA) is a helpful tool not only in cancer treatment, but also in the early detection of relapse. However, the clinical interpretation of a ctDNA negative result remains challenging. The characteriza
Externí odkaz:
https://doaj.org/article/e39cda56d70240f48db2b0d280f75cff
Autor:
Anne-Sophie Wozny, Gersende Alphonse, Audrey Cassard, Céline Malésys, Safa Louati, Michael Beuve, Philippe Lalle, Dominique Ardail, Tetsuo Nakajima, Claire Rodriguez-Lafrasse
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract DNA double-strand breaks (DSBs) induced by photon irradiation are the most deleterious damage for cancer cells and their efficient repair may contribute to radioresistance, particularly in hypoxic conditions. Carbon ions (C-ions) act indepen
Externí odkaz:
https://doaj.org/article/b9246a0bfb4742b4a947afac465121a4
Autor:
Jessica Garcia, Anne‐Sophie Wozny, Florence Geiguer, Aurélia Delherme, David Barthelemy, Patrick Merle, Claire Tissot, Frederick S. Jones, Chassidy Johnson, Xiaobin Xing, Zhenyu Xu, Daniel L. Edelstein, Marie Brevet, Pierre‐Jean Souquet, Claire Rodriguez‐Lafrasse, Léa Payen, Sébastien Couraud
Publikováno v:
Cancer Medicine, Vol 8, Iss 8, Pp 3685-3697 (2019)
Abstract Cell‐free plasma DNA (cfDNA) and mimicking circulating tumor cells (mCTCs) have demonstrated tremendous potential for molecular diagnosis of cancer and have been rapidly implemented in specific settings. However, widespread clinical adopti
Externí odkaz:
https://doaj.org/article/7a9999a583fd4631af8c0d011cb7254c
Dual 'mAb' HER family blockade in head and neck cancer human cell lines combined with photon therapy
Autor:
Jean-Baptiste Guy, Benoîte Méry, Edouard Ollier, Sophie Espenel, Alexis Vallard, Anne-Sophie Wozny, Stéphanie Simonet, Alexandra Lauret, Priscillia Battiston-Montagne, Dominique Ardail, Gersende Alphonse, Chloé Rancoule, Claire Rodriguez-Lafrasse, Nicolas Magné
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Head and neck cancer stem cells (CSCs) are highly resistant to treatment. When EGFR is overexpressed in head and neck squamous cell carcinoma (HNSCC), HER2 and HER3 are also expressed. The aim of the present study was to investigate the effe
Externí odkaz:
https://doaj.org/article/25541696948a416d88c4361dcc1a3747
Publikováno v:
British Journal of Cancer. 128:1429-1438
Numerous studies have demonstrated the higher biological efficacy of carbon-ion irradiation (C-ions) and their ballistic precision compared with photons. At the nanometre scale, the reactive oxygen species (ROS) produced by radiation and responsible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d72bc5cb003a9cae9495893a7bf8d34
https://doi.org/10.1038/s41416-022-02117-6
https://doi.org/10.1038/s41416-022-02117-6
Autor:
David Barthelemy, Gaelle Lescuyer, Florence Geiguer, Emmanuel Grolleau, Arnaud Gauthier, Julie Balandier, Margaux Raffin, Claire Bardel, Bruno Bouyssounouse, Claire Rodriguez-Lafrasse, Sébastien Couraud, Anne-Sophie Wozny, Léa Payen
Publikováno v:
Cancers
Volume 15
Issue 5
Pages: 1574
Volume 15
Issue 5
Pages: 1574
Introduction: Progressive advanced non-small cell lung cancer (NSCLC) accounts for about 80–85% of all lung cancers. Approximately 10–50% of patients with NSCLC harbor targetable activating mutations, such as in-frame deletions in Exon 19 (Ex19de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9116261acf155533fa4e50dee94e53
Autor:
Nicolas Vial, Sophie Espenel, Claire Rodriguez-Lafrasse, Anne-Sophie Wozny, Dominique Ardail, Nicolas Magné, M.-A. Garcia, Safa Louati, Arnaud Gauthier, Gersende Alphonse, Jean-Baptiste Guy, Céline Malésys
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Journal of Cancer Research and Clinical Oncology, Springer Verlag, 2021, 147 (7), pp.1905-1916. ⟨10.1007/s00432-021-03593-8⟩
Journal of Cancer Research and Clinical Oncology, Springer Verlag, 2021, 147 (7), pp.1905-1916. ⟨10.1007/s00432-021-03593-8⟩
International audience; PurposeThe clinical outcome of head and neck squamous cell carcinoma (HNSCC) remains poor, partly due to the presence of resistant cancer stem cells (CSCs) which are responsible of recurrences. CSCs have low EGFR expression an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9729b50e7981ba5c11d16531b65c3d
https://doi.org/10.1007/s00432-021-03593-8
https://doi.org/10.1007/s00432-021-03593-8
Autor:
Emmanuel Grolleau, Julie Candiracci, Arnaud Gauthier, Gaelle Lescuyer, David Barthelemy, Christine Haon, Florence Geiguer, Margaux Raffin, Nathalie Hardat, Julie Balandier, Rémi Rabeuf, Anne-Sophie Wozny, Guillaume Rommelaere, Claire Rodriguez-Lafrasse, Fabien Subtil, Sébastien Couraud, Marielle Herzog, Lea Payen-Gay
Publikováno v:
Cancer Research. 83:2163-2163
Introduction: Treatment options of lung cancer (LC) comprise radiotherapy, and/or combined treatment approaches, including chemotherapy, immunotherapy and targeted therapies based on the tumoral molecular profile. Following curative-intent first-line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d59e549eb704d2358eb0d13ed6b5712f
https://doi.org/10.1158/1538-7445.am2023-2163
https://doi.org/10.1158/1538-7445.am2023-2163
Autor:
David Barthelemy, Emmanuel Grolleau, Gaelle Lescuyer, Florence Geiguer, Arnaud Gauthier, Julie Balandier, Margaux Raffin, Claire Bardel, Bruno Bouyssounouse, Claire Rodriguez-Lafrasse, Sébastien Couraud, Anne-Sophie Wozny, Lea Payen-Gay
Publikováno v:
Cancer Research. 83:6691-6691
Background: Noninvasive genotyping using plasma cell-free DNA (cfDNA) has the potential to obviate the need for some invasive biopsies in cancer patients. We sought to validate an ultra-deep plasma Next-Generation Sequencing (NGS) assay for patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0119f7a641da22ebae657d9aa38ff81
https://doi.org/10.1158/1538-7445.am2023-6691
https://doi.org/10.1158/1538-7445.am2023-6691
Autor:
Pierre Philouze, Arnaud Gauthier, Alexandra Lauret, Céline Malesys, Giovanna Muggiolu, Sylvie Sauvaigo, Antoine Galmiche, Philippe Ceruse, Gersende Alphonse, Anne-Sophie Wozny, Claire Rodriguez-Lafrasse
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 877, p 877 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 877
International Journal of Molecular Sciences, Vol 23, Iss 877, p 877 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 877
Squamous cell carcinoma is the most common type of head and neck cancer (HNSCC) with a disease-free survival at 3 years that does not exceed 30%. Biomarkers able to predict clinical outcomes are clearly needed. The purpose of this study was to invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b7d3a9cedc2a02e81598a927caf803
http://europepmc.org/articles/PMC8775909
http://europepmc.org/articles/PMC8775909