Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anne-Sophie Thorup"'
Autor:
Sara Caxaria, Nikolaos Kouvatsos, Suzanne E Eldridge, Mario Alvarez‐Fallas, Anne‐Sophie Thorup, Daniela Cici, Aida Barawi, Ammaarah Arshed, Danielle Strachan, Giulia Carletti, Xinying Huang, Sabah Bharde, Melody Deniz, Jacob Wilson, Bethan L Thomas, Costantino Pitzalis, Francesco Paolo Cantatore, Manasi Sayilekshmy, Shafaq Sikandar, Frank P Luyten, Thomas Pap, Joanna C Sherwood, Anthony J Day, Francesco Dell'Accio
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 1, Pp n/a-n/a (2023)
Abstract We showed that the chemokine receptor C‐X‐C Motif Chemokine Receptor 2 (CXCR2) is essential for cartilage homeostasis. Here, we reveal that the CXCR2 ligand granulocyte chemotactic protein 2 (GCP‐2) was expressed, during embryonic deve
Externí odkaz:
https://doaj.org/article/c6ccca64be374eba90196cda5f86dbe7
Autor:
Giovanna Nalesso, Anne-Sophie Thorup, Suzanne Elizabeth Eldridge, Anna De Palma, Amanpreet Kaur, Kiran Peddireddi, Kevin Blighe, Sharmila Rana, Bryony Stott, Tonia Louise Vincent, Bethan Lynne Thomas, Jessica Bertrand, Joanna Sherwood, Antonella Fioravanti, Costantino Pitzalis, Francesco Dell’Accio
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract WNT ligands can activate several signalling cascades of pivotal importance during development and regenerative processes. Their de-regulation has been associated with the onset of different diseases. Here we investigated the role of the WNT/
Externí odkaz:
https://doaj.org/article/4f50238f6e9a41a8bd45f631bc8299e2
Autor:
Bethan L. Thomas, Suzanne E. Eldridge, Babak Nosrati, Mario Alvarez, Anne‐Sophie Thorup, Giovanna Nalesso, Sara Caxaria, Aida Barawi, James G. Nicholson, Mauro Perretti, Carles Gaston‐Massuet, Costantino Pitzalis, Alison Maloney, Adrian Moore, Ray Jupp, Francesco Dell'Accio
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 7, Pp n/a-n/a (2021)
Abstract Cartilage defects repair poorly. Recent genetic studies suggest that WNT3a may contribute to cartilage regeneration, however the dense, avascular cartilage extracellular matrix limits its penetration and signalling to chondrocytes. Extracell
Externí odkaz:
https://doaj.org/article/1e6db36139a04cbf8ffe4756c472fec6
Autor:
Anne-Sophie Thorup, Sara Caxaria, Bethan L. Thomas, Yasir Suleman, Giovanna Nalesso, Frank P. Luyten, Francesco Dell’Accio, Suzanne E. Eldridge
Publikováno v:
Lab Animal. 51:103-120
Cartilage regeneration is a priority in medicine for the treatment of osteoarthritis and isolated cartilage defects. Several molecules with potential for cartilage regeneration are under investigation. Unfortunately, in vitro chondrogenesis assays do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd03d6be2571acae1d034d25d531dd6
https://doi.org/10.1038/s41684-022-00943-y
https://doi.org/10.1038/s41684-022-00943-y
Publikováno v:
Cartilage Tissue Engineering ISBN: 9781071628386
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee3e8ab407001459eba54ce37258bc62
https://doi.org/10.1007/978-1-0716-2839-3_24
https://doi.org/10.1007/978-1-0716-2839-3_24
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2598
Chondral defects are common and disabling. The development of pharmacological approaches for cartilage repair requires the availability of in vivo models which are amenable for gain and loss of function and ideally to genetic modification. In this ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b8dd535b43d6c0574700d3aaecd15bc
https://pubmed.ncbi.nlm.nih.gov/36355303
https://pubmed.ncbi.nlm.nih.gov/36355303
Publikováno v:
Developmental Dynamics. 250:360-376
More than 250 years ago, William Hunter stated that when cartilage is destroyed it never recovers. In the last 20 years, the understanding of the mechanisms that lead to joint formation and the knowledge that some of these mechanisms are reactivated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7575bb948ca9d66b5216ccdf9a8dcc20
https://doi.org/10.1002/dvdy.228
https://doi.org/10.1002/dvdy.228
Autor:
James G. Nicholson, Costantino Pitzalis, Alison Maloney, Mario Alvarez, S.E. Eldridge, Carles Gaston-Massuet, Ray Jupp, G. Nalesso, B.L. Thomas, Babak Nosrati, Adrian Moore, Mauro Perretti, Anne-Sophie Thorup, Aida Barawi, Francesco Dell'Accio, S. Caxaria
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 7, Pp n/a-n/a (2021)
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles
Cartilage defects repair poorly. Recent genetic studies suggest that WNT3a may contribute to cartilage regeneration, however the dense, avascular cartilage extracellular matrix limits its penetration and signalling to chondrocytes. Extracellular vesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238d3c0c958dfd0d5a6eabd362de5752
https://doaj.org/article/1e6db36139a04cbf8ffe4756c472fec6
https://doaj.org/article/1e6db36139a04cbf8ffe4756c472fec6
Autor:
Jessica Bertrand, Kiran Peddireddi, Costantino Pitzalis, Amanpreet Kaur, K. Blighe, J. Sherwood, G. Nalesso, Antonella Fioravanti, Anne-Sophie Thorup, S.E. Eldridge, Sharmila Rana, B. Stott, B.L. Thomas, Tonia L. Vincent, Francesco Dell'Accio, Anna De Palma
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
WNT ligands can activate several signalling cascades of pivotal importance during development and regenerative processes. Their de-regulation has been associated with the onset of different diseases. Here we investigated the role of the WNT/Calcium C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3dc0c47bbed496ea338a2283590b7b
http://europepmc.org/articles/PMC7952598
http://europepmc.org/articles/PMC7952598
Autor:
Magdalena Kaneva, B.L. Thomas, D. Strachan, Anne-Sophie Thorup, S. Caxaria, Kanatheepan Shanmuganathan, Anke J. Roelofs, Ahmed Ali, S.E. Eldridge, Andrew McCaskie, Aida Barawi, Costantino Pitzalis, James R. Whiteford, Francesco Dell'Accio, Beatriz F. Fernandez, Frances Henson, Helen Lydon, H. Wang, Zeyu Guan, Cosimo De Bari
Cartilage loss leads to osteoarthritis, the most common cause of disability for which there is no cure. Cartilage regeneration, therefore, is a priority in medicine. We report that agrin is a potent chondrogenic factor and that a single intraarticula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b385b6448cc7ad68bf28553aa31d2c