Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2.

Autor: Tomas Kirchhoff, Mia M Gaudet, Antonis C Antoniou, Lesley McGuffog, Manjeet K Humphreys, Alison M Dunning, Stig E Bojesen, Børge G Nordestgaard, Henrik Flyger, Daehee Kang, Keun-Young Yoo, Dong-Young Noh, Sei-Hyun Ahn, Thilo Dork, Peter Schürmann, Johann H Karstens, Peter Hillemanns, Fergus J Couch, Janet Olson, Celine Vachon, Xianshu Wang, Angela Cox, Ian Brock, Graeme Elliott, Malcolm W R Reed, Barbara Burwinkel, Alfons Meindl, Hiltrud Brauch, Ute Hamann, Yon-Dschun Ko, GENICA Network, Annegien Broeks, Marjanka K Schmidt, Laura J Van 't Veer, Linde M Braaf, Nichola Johnson, Olivia Fletcher, Lorna Gibson, Julian Peto, Clare Turnbull, Sheila Seal, Anthony Renwick, Nazneen Rahman, Pei-Ei Wu, Jyh-Cherng Yu, Chia-Ni Hsiung, Chen-Yang Shen, Melissa C Southey, John L Hopper, Fleur Hammet, Thijs Van Dorpe, Anne-Sophie Dieudonne, Sigrid Hatse, Diether Lambrechts, Irene L Andrulis, Natalia Bogdanova, Natalia Antonenkova, Juri I Rogov, Daria Prokofieva, Marina Bermisheva, Elza Khusnutdinova, Christi J van Asperen, Robert A E M Tollenaar, Maartje J Hooning, Peter Devilee, Sara Margolin, Annika Lindblom, Roger L Milne, José Ignacio Arias, M Pilar Zamora, Javier Benítez, Gianluca Severi, Laura Baglietto, Graham G Giles, kConFab, AOCS Study Group, Amanda B Spurdle, Jonathan Beesley, Xiaoqing Chen, Helene Holland, Sue Healey, Shan Wang-Gohrke, Jenny Chang-Claude, Arto Mannermaa, Veli-Matti Kosma, Jaana Kauppinen, Vesa Kataja, Bjarni A Agnarsson, Maria A Caligo, Andrew K Godwin, Heli Nevanlinna, Tuomas Heikkinen, Zachary Fredericksen, Noralane Lindor, Katherine L Nathanson, Susan M Domchek, SWE-BRCA, Niklas Loman, Per Karlsson, Marie Stenmark Askmalm, Beatrice Melin, Anna von Wachenfeldt, HEBON, Frans B L Hogervorst, Martijn Verheus, Matti A Rookus, Caroline Seynaeve, Rogier A Oldenburg, Marjolijn J Ligtenberg, Margreet G E M Ausems, Cora M Aalfs, Hans J P Gille, Juul T Wijnen, Encarna B Gómez García, EMBRACE, Susan Peock, Margaret Cook, Clare T Oliver, Debra Frost, Craig Luccarini, Gabriella Pichert, Rosemarie Davidson, Carol Chu, Diana Eccles, Kai-Ren Ong, Jackie Cook, Fiona Douglas, Shirley Hodgson, D Gareth Evans, Rosalind Eeles, Bert Gold, Paul D P Pharoah, Kenneth Offit, Georgia Chenevix-Trench, Douglas F Easton, BCAC/CIMBA

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e35706 (2012)

Recently, a locus on chromosome 6q22.33 (rs2180341) was reported to be associated with increased breast cancer risk in the Ashkenazi Jewish (AJ) population, and this association was also observed in populations of non-AJ European ancestry. In the pre

Externí odkaz: https://doaj.org/article/1433592c7c844e02a12dd57e5bf1a0a8

Supplementary Tables 1-13 from 19p13.1 Is a Triple-Negative–Specific Breast Cancer Susceptibility Locus

Autor: Fergus J. Couch, Douglas F. Easton, Ylermi Soini, Jaana M. Hartikainen, Veli-Matti Kosma, Arto Mannermaa, Xiaoqing Chen, Jonathan Beesley, Georgia Chenevix-Trench, Marie-Rose Christiaens, Anne-Sophie Dieudonne, Sigrid Hatse, Diether Lambrechts, Monica Barile, Siranoush Manoukian, Paolo Peterlongo, Paolo Radice, Janet E. Olson, Susan Slager, V.S. Pankratz, Matthew L. Kosel, Gianluca Severi, Catriona A. McLean, Laura Baglietto, Graham G. Giles, Anne-Lise Børresen-Dale, Vessela Kristensen, Grethe Grenaker Alnæs, Alexander Miron, Esther M. John, Mervi Grip, Arja Jukkola-Vuorinen, Katri Pylkäs, Robert Winqvist, Anna Marie Mulligan, Gord Glendon, Julia A. Knight, Irene L. Andrulis, Maartje J. Hooning, Rob A.E.M. Tollenaar, Caroline Seynaeve, Peter Devilee, Jolanta Lissowska, Mark E. Sherman, Jonine D. Figueroa, Montserrat Garcia-Closas, Diana M. Eccles, Helena Hwang, Foluso Ademuyiwa, Christine B. Ambrosone, Kamila Czene, Per Hall, Malcom W. Reed, Simon S. Cross, Angela Cox, Qin Wang, Manjeet K. Humphreys, Alison M. Dunning, Paul P. Pharoah, Hans Ulrich Ulmer, Thomas Rüdiger, Thomas Dünnebier, Ute Hamann, Chia-Ni Hsiung, Huan-Ming Hsu, Jyh-Cherng Yu, Chen-Yang Shen, Christina Clarke Dur, Leslie Bernstein, Argyrios Ziogas, Hoda Anton-Culver, Minouk J. Schoemaker, Nicholas Orr, Alan Ashworth, Anthony J. Swerdlow, Melissa C. Southey, Daniel J. Park, Carmel Apicella, John L. Hopper, Efraim H. Rosenberg, Linde M. Braaf, Annegien Broeks, Marjanka K. Schmidt, Surapon Wiangnon, Puttisak Puttawibul, Kenneth Muir, Artitaya Lophatananon, Arif B. Ekici, Arndt Hartmann, Matthias W. Beckmann, Peter A. Fasching, Isabel dos Santos Silva, Olivia Fletcher, Nichola Johnson, Julian Peto, Michael J. Kerin, Ian Tomlinson, Elinor Sawyer, Christof Sohn, Andreas Schneeweiss, Frederick Marmé, Barbara Burwinkel, Emilie Cordina-Duverger, Florence Menegaux, Thérèse Truong, Pascal Guénel, Henrik Flyger, Børge G. Nordestgaard, Sune F. Nielsen, Stig E. Bojesen, José Ignacio Arias Pérez, María Pilar Zamora, Javier Benítez, Roger L. Milne, Annie Perkins, Miriam Dwek, Ruth Swann, Helen J. Gogas, George Fountzilas, Alexandra Stavropoulou, Drakoulis Yannoukakos, Penelope Miron, Christa Stegmaier, Volker Arndt, Heiko Müller, Hermann Brenner, Priyanka Sharma, Harsh B. Pathak, JoEllen Weaver, Andrew K. Godwin, Christoph Engel, Sarah Schott, Claus R. Bartram, Alfons Meindl, Rita K. Schmutzler, Hans-Peter Fischer, Yon-Dschun Ko, Hiltrud Brauch, Stefan Nickels, Shan Wang-Gohrke, Hans-Peter Sinn, Dieter Flesch-Janys, Alina Vrieling, Jenny Chang-Claude, Carl Blomqvist, Kristiina Aittomäki, Dario Greco, Heli Nevanlinna, Annika Lindblom, Sara Margolin, Xianshu Wang, Celine M. Vachon, Zachary Fredericksen, Kristen N. Stevens

PDF file - 272K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739f2fe1c24891c344f70a4e8949d5d0
https://doi.org/10.1158/0008-5472.22393569.v1

The role of genetic breast cancer susceptibility variants as prognostic factors

Autor: Laura J. van't Veer, John W.M. Martens, Erik Van Limbergen, Jenny Chang-Claude, Alison M. Dunning, Sabapathy P. Balasubramanian, Janet E. Olson, Sara Margolin, Mitul Shah, Matthias W. Beckmann, Malcolm W.R. Reed, Manjeet K. Humphreys, Mark E. Sherman, Douglas F. Easton, Graham G. Giles, Anne Sophie Dieudonne, Bernardo Bonanni, Marjanka K. Schmidt, Saila Kauppila, Thilo Dörk, Michael Bremer, Arja Jukkola-Vuorinen, Peter A. Fasching, Sara J. Schonfeld, Laura Baglietto, Annegien Broeks, Stig E. Bojesen, Stefan Nickels, Carl Blomqvist, Kamila Czene, Javier Benitez, Hilmi Ozcelik, John L. Hopper, Frederik Marmé, Paolo Peterlongo, Simon S. Cross, Melissa C. Southey, Maria Schiekel, Robert Winqvist, Paul D.P. Pharoah, Alexander Miron, Agnes Jager, Jose Ignacio Arias Perez, M. Pilar Zamora, Esther M. John, Matthew L. Kosel, Diether Lambrechts, Henrik Flyger, Sigrid Hatse, Tjoung Won Park-Simon, Per Hall, Petra E A Huijts, Jonine D. Figueroa, Irene L. Andrulis, Dario Greco, Hoda Anton-Culver, Veli-Matti Kosma, Kelly-Anne Phillips, Arto Mannermaa, Claudia Rauh, Fergus J. Couch, Andreas Schneeweiss, Flora E. van Leeuwen, Kristen N. Stevens, Annika Lindblom, Bernard Peissel, Georgia Chenevix-Trench, Arif B. Ekici, Preetha Rajaraman, Shan Wang-Gohrke, Dennis J. Slamon, Jianjun Liu, M.J. Hooning, Jaana M. Hartikainen, Montserrat Garcia-Closas, Katri Pylkäs, Roger L. Milne, Christof Sohn, Peter Devilee, Gianluca Severi, Ursula Eilber, Kristiina Aittomäki, Vesa Kataja, Børge G. Nordestgaard, Rob A. E. M. Tollenaar, Anna Marie Mulligan, Argyrios Ziogas, Barbara Burwinkel, Caroline Seynaeve, Bernard Loris, Mieke Kriege, Renate Udo, Gord Glendon, Carmel Apicella, Heli Nevanlinna, Thomas Karn, Jolanta Lissowska, Angela Cox

Publikováno v: Human Molecular Genetics, 21(17), 3926-3939
Human Molecular Genetics, 21(17), 3926-3939. Oxford University Press
Human Molecular Genetics

Recent genome-wide association studies identified 11 single nucleotide polymorphisms (SNPs) associated with breast cancer (BC) risk. We investigated these and 62 other SNPs for their prognostic relevance. Confirmed BC risk SNPs rs17468277 (CASP8), rs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fa8ce4b13f4b7f1205a8d059a52b44