Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Anne-Sophie Beignon"'
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
Autoimmune disorders have been well characterized over the years and many pathways—but not all of them–have been found to explain their pathophysiology. Autoinflammatory disorders, on the other hand, are still hiding most of their molecular and c
Externí odkaz:
https://doaj.org/article/e97a49c2b3e74d22a3fa89e50326fc49
Autor:
Yanis Feraoun, Jean-Louis Palgen, Candie Joly, Nicolas Tchitchek, Ernesto Marcos-Lopez, Nathalie Dereuddre-Bosquet, Anne-Sophie Gallouet, Vanessa Contreras, Yves Lévy, Frédéric Martinon, Roger Le Grand, Anne-Sophie Beignon
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Innate immunity modulates adaptive immunity and defines the magnitude, quality, and longevity of antigen-specific T- and B- cell immune memory. Various vaccine and administration factors influence the immune response to vaccination, including the rou
Externí odkaz:
https://doaj.org/article/4e8d67227a834e9ea0caf0bc8cc56a37
Autor:
Nicolas Huot, Philippe Rascle, Cyril Planchais, Vanessa Contreras, Caroline Passaes, Roger Le Grand, Anne-Sophie Beignon, Etienne Kornobis, Rachel Legendre, Hugo Varet, Asier Saez-Cirion, Hugo Mouquet, Beatrice Jacquelin, Michaela Müller-Trutwin
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
CD4 T cell responses constitute an important component of adaptive immunity and are critical regulators of anti-microbial protection. CD4+ T cells expressing CD32a have been identified as a target for HIV. CD32a is an Fcγ receptor known to be expres
Externí odkaz:
https://doaj.org/article/a38fd0b7ff664f578c3ff4a72937a819
Vaccine Inoculation Route Modulates Early Immunity and Consequently Antigen-Specific Immune Response
Autor:
Pierre Rosenbaum, Nicolas Tchitchek, Candie Joly, André Rodriguez Pozo, Lev Stimmer, Sébastien Langlois, Hakim Hocini, Leslie Gosse, David Pejoski, Antonio Cosma, Anne-Sophie Beignon, Nathalie Dereuddre-Bosquet, Yves Levy, Roger Le Grand, Frédéric Martinon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Vaccination is one of the most efficient public healthcare measures to fight infectious diseases. Nevertheless, the immune mechanisms induced in vivo by vaccination are still unclear. The route of administration, an important vaccination parameter, c
Externí odkaz:
https://doaj.org/article/3a103ecb80fc4060981474719f13c5bd
Autor:
Jean-Louis Palgen, Yanis Feraoun, Gaëlle Dzangué-Tchoupou, Candie Joly, Frédéric Martinon, Roger Le Grand, Anne-Sophie Beignon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Most vaccines require multiple doses to induce long-lasting protective immunity in a high frequency of vaccines, and to ensure strong both individual and herd immunity. Repetitive immunogenic stimulations not only increase the intensity and durabilit
Externí odkaz:
https://doaj.org/article/1fdda03a6e724539992f0e1fc027b389
Autor:
Nicolas Huot, Philippe Rascle, Caroline Petitdemange, Vanessa Contreras, Jean-Louis Palgen, Christiane Stahl-Hennig, Roger Le Grand, Anne-Sophie Beignon, Beatrice Jacquelin, Michaela Müller-Trutwin
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Natural killer (NK) cells play essential roles in immunity to viruses and tumors. Their function is genetically determined but also modulated by environmental factors. The distribution and functional regulation of these cells vary depending on the ti
Externí odkaz:
https://doaj.org/article/74cb0d2463a34ce1b9a869ea2cf83272
Autor:
Matthieu Van Tilbeurgh, Katia Lemdani, Anne-Sophie Beignon, Catherine Chapon, Nicolas Tchitchek, Lina Cheraitia, Ernesto Marcos Lopez, Quentin Pascal, Roger Le Grand, Pauline Maisonnasse, Caroline Manet
Publikováno v:
Vaccines, Vol 9, Iss 6, p 579 (2021)
Vaccines represent one of the major advances of modern medicine. Despite the many successes of vaccination, continuous efforts to design new vaccines are needed to fight “old” pandemics, such as tuberculosis and malaria, as well as emerging patho
Externí odkaz:
https://doaj.org/article/7224b46bc312470e8b05266dae28b71e
Autor:
Sixtine Coindre, Nicolas Tchitchek, Lamine Alaoui, Bruno Vaslin, Christine Bourgeois, Cecile Goujard, Camille Lecuroux, Pierre Bruhns, Roger Le Grand, Anne-Sophie Beignon, Olivier Lambotte, Benoit Favier
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Dendritic cells (DC), which are involved in orchestrating early immune responses against pathogens, are dysregulated in their function by HIV infection. This dysregulation likely contributes to tip the balance toward viral persistence. Different DC s
Externí odkaz:
https://doaj.org/article/30f6e6b2b8fd4de2b46db5ac70dbe63b
Autor:
Débora M. Portilho, Juliette Fernandez, Mathieu Ringeard, Anthony K. Machado, Aude Boulay, Martha Mayer, Michaela Müller-Trutwin, Anne-Sophie Beignon, Frank Kirchhoff, Sébastien Nisole, Nathalie J. Arhel
Publikováno v:
Cell Reports, Vol 14, Iss 2, Pp 355-369 (2016)
During retroviral infection, viral capsids are subject to restriction by the cellular factor TRIM5α. Here, we show that dendritic cells (DCs) derived from human and non-human primate species lack efficient TRIM5α-mediated retroviral restriction. In
Externí odkaz:
https://doaj.org/article/8d02ae9682ae4e949525b50e8f892dc4
Autor:
Sixtine Coindre, Nicolas Tchitchek, Lamine Alaoui, Bruno Vaslin, Christine Bourgeois, Cecile Goujard, Veronique Avettand-Fenoel, Camille Lecuroux, Pierre Bruhns, Roger Le Grand, Anne-Sophie Beignon, Olivier Lambotte, Benoit Favier, The ANRS CO6 PRIMO Cohort
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
CD32a has been proposed as a specific marker of latently HIV-infected CD4+ T cells. However, CD32a was recently found to be expressed on CD4+ T cells of healthy donors, leading to controversy on the relevance of this marker in HIV persistence. Here,
Externí odkaz:
https://doaj.org/article/112139af2afc4ae8ba8a0a13701f1b02