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Autor:
Richard J. Bende, Marcel Spaargaren, Anne-Pauline van Huijstee, Hiroaki Kataoka, Patrick W. B. Derksen, Steven T. Pals, Esther P. M. Tjin
Publikováno v:
Journal of immunology (Baltimore, Md., 175(5), 2807-2813. American Association of Immunologists
Ag-specific B cell differentiation, the process that gives rise to plasma cells and memory B cells, involves the formation of germinal centers (GC). Within the GC microenvironment, multiple steps of B cell proliferation, selection, and maturation tak