Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anne-Marie Schönegge"'
Autor:
Anne-Marie Schönegge, Jonathan Gallion, Louis-Philippe Picard, Angela D. Wilkins, Christian Le Gouill, Martin Audet, Wayne Stallaert, Martin J. Lohse, Marek Kimmel, Olivier Lichtarge, Michel Bouvier
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Ligand-induced biased signaling is thought to result in part from ligand-specific receptor conformations that cause the engagement of distinct effectors. Here the authors trace and evaluate the impact of mutations of the β2–adrenergic receptor on
Externí odkaz:
https://doaj.org/article/998b6cae615e45acb325e0d14982a595
Publikováno v:
Nature Protocols. 14:1084-1107
Bioluminescence resonance energy transfer (BRET) is a transfer of energy between a luminescence donor and a fluorescence acceptor. Because BRET occurs when the distance between the donor and acceptor is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e64619f31e1e03661b8cb13e2af43c95
https://doi.org/10.1038/s41596-019-0129-7
https://doi.org/10.1038/s41596-019-0129-7
Autor:
Michel Bouvier, Junken Aoki, Bianca Plouffe, Christian Le Gouill, Wayne Stallaert, Emma T van der Westhuizen, Viktoria Lukashova, Anne Marie Schönegge, Asuka Inoue, Satoru Ishida, Mireille Hogue
Publikováno v:
Molecular Pharmacology. 91:533-544
The β2 adrenergic receptor (β2AR) increases intracellular Ca2+ in a variety of cell types. By combining pharmacological and genetic manipulations, we reveal a novel mechanism through which the β2AR promotes Ca2+ mobilization (pEC50 = 7.32 ± 0.10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36a9d06d74079c2e5d0bbca6643c8cd8
https://doi.org/10.1124/mol.116.106419
https://doi.org/10.1124/mol.116.106419
[Image: see text] G protein-coupled receptors (GPCRs) form the largest family of membrane proteins involved in signal transduction. Because of their ability to regulate a wide range of cellular responses and their dysregulation being associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf04770a44ef7cfa4c2299fecd2e34b
https://europepmc.org/articles/PMC7088954/
https://europepmc.org/articles/PMC7088954/
Publikováno v:
Nature protocols. 14(4)
Bioluminescence resonance energy transfer (BRET) is a transfer of energy between a luminescence donor and a fluorescence acceptor. Because BRET occurs when the distance between the donor and acceptor is10 nm, and its efficiency is inversely proportio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2837d8bf593d9fbe2ac4acf3aa7f97a0
https://pubmed.ncbi.nlm.nih.gov/30911173
https://pubmed.ncbi.nlm.nih.gov/30911173
Autor:
Martin Audet, Martin J. Lohse, Michel Bouvier, Jonathan Gallion, Angela D. Wilkins, Wayne Stallaert, Christian Le Gouill, Louis-Philippe Picard, Olivier Lichtarge, Anne-Marie Schönegge, Marek Kimmel
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Functional selectivity of G-protein-coupled receptors is believed to originate from ligand-specific conformations that activate only subsets of signaling effectors. In this study, to identify molecular motifs playing important roles in transducing li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc9b8c5d0a3f6a685e0b9b1b4df09a0
https://doi.org/10.1038/s41467-017-02257-x
https://doi.org/10.1038/s41467-017-02257-x
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-7 (2018)
G protein-coupled receptors (GPCRs) are seven-transmembrane proteins that mediate a variety of cellular response which make them a target of choice for drug development in many indications. It is now well established that GPCRs can adopt several dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdaf8f9a4c28ceea85f597b75adfb29e
https://pubmed.ncbi.nlm.nih.gov/30271986
https://pubmed.ncbi.nlm.nih.gov/30271986
Autor:
Wayne, Stallaert, Emma T, van der Westhuizen, Anne-Marie, Schönegge, Bianca, Plouffe, Mireille, Hogue, Viktoria, Lukashova, Asuka, Inoue, Satoru, Ishida, Junken, Aoki, Christian, Le Gouill, Michel, Bouvier
Publikováno v:
Molecular pharmacology. 91(5)
The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04f22aff474a69c715ed4f711eb2f8f8
https://pubmed.ncbi.nlm.nih.gov/28280061
https://pubmed.ncbi.nlm.nih.gov/28280061
Autor:
Elizabeth Villa, Friedrich Förster, Beate Rockel, Anne-Marie Schönegge, Reiner Hegerl, Jürgen Peters, Wolfgang Baumeister
Publikováno v:
Structure. 20(4):593-603
SummaryTripeptidyl-peptidase II (TPPII) is a high molecular mass (∼5 MDa) serine protease, which is thought to act downstream of the 26S proteasome, cleaving peptides released by the latter. Here, the structure of human TPPII (HsTPPII) has been det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb355486d85c472d88d788b11d0468a4
Publikováno v:
Biophysical Journal. 114:537a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b189c397f7b36fcd1ccf1839048b0fb
https://doi.org/10.1016/j.bpj.2017.11.2936
https://doi.org/10.1016/j.bpj.2017.11.2936