Výsledky vyhledávání - "Anne-Marie Renault"

Abstract 3733: SilenciX®, novel stable knock-down cellular models to screen new molecular targets through the synthetic lethality approach

Autor: Isabelle Fixe, Nadia Normand, Claudine Kieda, Catherine Grillon, Anne-Marie Renault, Eric Mennesson

Publikováno v: Cancer Research. 74:3733-3733

PARP inhibitors are promising therapeutic drugs for cancers harboring BRCA1 and BRCA2 mutations. PARP is involved in the Base Excision Repair (BER) DNA repair pathway. Tumors with BRCA mutations are deficient in Homologous Recombination (HR), another

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c88814fd4517372e9d152bc455e09314
https://doi.org/10.1158/1538-7445.am2014-3733

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