Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Anne-Marie Preaux"'
Autor:
Philippe Mavier, Anne-Marie Preaux, Aida Habib, Jacques Maclouf, Cyrille Gallois, Ariane Mallat, Sophie Lotersztajn, Jiangchuan Tao
Publikováno v:
Journal of Biological Chemistry. 273:27300-27305
Proliferation of myofibroblastic hepatic stellate cells (HSC) in response to growth factors is essential for the development of liver fibrosis. We have reported that prostaglandins (PG) and cyclic AMP (cAMP) inhibit growth of human HSC. This PG/cAMP
Autor:
Elie Serge Zafrani, Anne-Marie Preaux, Daniel Cherqui, Ariane Mallat, Jeanne Tran Van Nhieu, Philippe Mavier, Isabelle Brocheriou
Publikováno v:
Journal of Hepatology. 29:120-128
Background/Aims: The number of perisinusoidal myofibroblasts has been shown to be increased in hepatocellular carcinoma, as compared to cirrhosis. This increase might suggest a cooperative relationship between tumour cells and myofibroblasts. To asse
Autor:
C Serradeil-Le Gal, V Iourgenko, Ariane Mallat, D A Brenner, Philippe Mavier, Laura Fouassier, Danielle Raufaste, Sophie Lotersztajn, Daniel Dhumeaux, Anne-Marie Preaux, C Bradham, Cyrille Gallois, Jacques Maclouf
Publikováno v:
Scopus-Elsevier
During chronic liver diseases, hepatic stellate cells (HSC) acquire an activated myofibroblast-like phenotype, proliferate, and synthetize fibrosis components. We have shown that endothelin-1 (ET-1) inhibits the proliferation of activated human HSC v
Autor:
Ariane Mallat, Sylvie Blazejewski, Philippe Mavier, Daniel Dhumeaux, Anne-Marie Preaux, Jean Rosenbaum
Publikováno v:
Gastroenterology. 109:1986-1996
Background & Aims: During liver fibrogenesis, myofibroblastic liver cells proliferate and synthesize components of fibrosis. Fibroblast growth factor 2 (FGF-2) is expressed in vivo in myofibroblastic liver cells (MFLCs) during fibrogenesis, and exoge
Autor:
Ariane Mallat, Sylvie Blazejewski, Daniel Dhumeaux, Anne-Marie Preaux, Detlef Schuppan, Jean Rosenbaum, Philippe Mavier, Daniel J. Hartmann, Isabelle Brocheriou
Publikováno v:
Hepatology. 22:788-797
During human fibrogenesis, myofibroblastlike cells proliferate and are the main source of fibrosis components. We have used cultured myofibroblastlike cells obtained by outgrowth from explants of human liver to study the expression of extracellular m
Autor:
Daniel Dhumeau, M D Jean Rosenbaum, Philippe Mavier, Ariane Mallat, Daniel Cherqui, Nadine Martin, Frédéric Charlotte, Anne-Marie Preaux, Khin Maung Win
Publikováno v:
Hepatology. 18:137-145
We assessed the effect of transforming growth factor-beta 1 on the proliferation of human Ito cells. Ito cells in their myofibroblastlike phenotype were grown from explants of human liver and were characterized with electron microscopy and positive i
Autor:
Jean Rosenbaum, Frederic Charlotte, Khin Maung Win, Elie Serge Zafrani, Daniel Dhumeaux, Anne-Marie Preaux, Philippe Mavier
Publikováno v:
The Journal of Pathology. 169:471-476
Ito cells play a major role in liver fibrosis but the mechanisms controlling their activation in vivo are poorly understood. Heparin-binding growth factors (HBGF) types 1 and 2 are mitogenic for cultured Ito cells. They have been found in liver extra
Publikováno v:
Hepatology (Baltimore, Md.). 36(3)
Liver fibrosis is potentially reversible after removal of the injurious agent. Fibrosis resolution is characterized by apoptosis of hepatic myofibroblasts and degradation of extracellular matrix components. Matrix metalloproteinase-2 (MMP-2) is invol
Autor:
Jacques Hanoune, C. Jouneaux, Anne-Marie Preaux, Danielle Raufaste, Corinne Garcia, Sophie Lotersztajn, Claudine Serradeil-Le Gal
Publikováno v:
Biochemical Pharmacology. 43:1146-1148
Publikováno v:
Hepatology (Baltimore, Md.). 26(2)
During the course of liver fibrogenesis, myofibroblast-like cells (MFLC), mostly derived from hepatic stellate cells, proliferate and synthesize excessive amounts of extracellular matrix components. Pentoxifylline (PTX) elicits antiproliferative and