Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Anne-Marie J. F. Boerboom"'
1
Pro-Oxidant Activity of Flavonoids Induces EpRE-Mediated Gene Expression
Autor: Jac M.M.J.G. Aarts, Ivonne M.C.M. Rietjens, Anne-Marie J. F. Boerboom, Willem J. H. van Berkel, Yee Y. Lee-Hilz, Adrie H. Westphal
Publikováno v: Chemical Research in Toxicology 19 (2006) 11
Chemical Research in Toxicology, 19(11), 1499-1505
Flavonoids are important bioactive dietary compounds. They induce electrophile-responsive element (EpRE)-mediated expression of enzymes, such as NAD(P)H-quinone oxidoreductase (NQO1) and glutathione S-transferases (GSTs), which are major defense enzy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18de9ca900f3cc19dbb03814cf25b957
https://doi.org/10.1021/tx060157q
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2
Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya
Autor: Ivonne M.C.M. Rietjens, Jac M.M.J.G. Aarts, Barry M.G. Blankvoort, Wouter H. J. Vaes, Martijn Vermeulen, Peter J. van Bladeren, Anne-Marie J. F. Boerboom
Publikováno v: Toxicology in Vitro 23 (2009) 4
Toxicology in Vitro, 4, 23, 617-621
Toxicology in Vitro, 23(4), 617-621
Isothiocyanates are electrophiles that are able to induce phase II biotransformation enzyme gene expression via an electrophile-responsive element (EpRE) in the gene regulatory region. To study the potency of different isothiocyanates to induce the e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7165ead19b5a61ca4d5428c65b9b5f
https://research.wur.nl/en/publications/potency-of-isothiocyanates-to-induce-luciferase-reporter-gene-exp
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3
The influence of fruit and vegetable consumption and genetic variation on NAD(P)H:quinone oxidoreductase (NQO1) phenotype in an endoscopy-based population
Autor: Frans J. Kok, Ivonne M.C.M. Rietjens, Fokko M. Nagengast, Adriaan C. I. T. L. Tan, Mariken J. Tijhuis, Anne-Marie J. F. Boerboom, Liesbeth Op den Camp, M.H.P.W. Visker, Ellen Kampman, Jac M.M.J.G. Aarts
Publikováno v: Nutrition and Cancer 60 (2008) 2
Nutrition and Cancer-An International Journal, 60, 204-15
Nutrition and Cancer-An International Journal, 60, 2, pp. 204-15
Nutrition and Cancer, 60(2), 204-215
Contains fulltext : 68313.pdf (Publisher’s version ) (Closed access) NAD(P)H:quinone oxidoreductase (NQO1) is an inducible detoxification enzyme relevant for colorectal cancer biochemoprevention. We evaluated the influence of recent fruit and veget
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf4b9bc1a21d3e829645172806b1d3c
https://doi.org/10.1080/01635580701684849
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4
Glutathione S-transferase phenotypes in relation to genetic variation and fruit and vegetable consumption in an endoscopy-based population
Autor: Jac M.M.J.G. Aarts, Anne-Marie J. F. Boerboom, Wilbert H.M. Peters, Mariken J. Tijhuis, M.H.P.W. Visker, Ivonne M.C.M. Rietjens, Ellen Kampman, Hennie M.J. Roelofs, Liesbeth Op den Camp, Fokko M. Nagengast, Frans J. Kok
Publikováno v: Carcinogenesis, 28, 848-57
Carcinogenesis, 28(4), 848-857
Carcinogenesis 28 (2007) 4
Carcinogenesis, 28, 4, pp. 848-57
Contains fulltext : 51701.pdf (Publisher’s version ) (Closed access) High glutathione S-transferase (GST) activity may contribute to colorectal cancer prevention. Functional polymorphisms are known in the GSTM1, GSTT1, GSTA1 and GSTP1 genes. The in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a693d5c52af3be48cbcbbe73f12f22e8
http://hdl.handle.net/2066/51701
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5
Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity
Autor: Jac M.M.J.G. Aarts, Yee Y. Lee-Hilz, Hester van der Woude, Ellen Kampman, Ivonne M.C.M. Rietjens, Martijn Vermeulen, Anne-Marie J. F. Boerboom, Birgit I. Bremer, Peter J. van Bladeren
Publikováno v: Biochemical Pharmacology, 2, 72, 217-226
Biochemical Pharmacology, 72, 217-26
Biochemical Pharmacology, 72(2), 217-226
Biochemical Pharmacology, 72, 2, pp. 217-26
Biochemical Pharmacology 72 (2006) 2
The electrophile-responsive element (EpRE) is a transcriptional enhancer involved in cancer-chemoprotective gene expression modulation by certain food components. Two stably transfected luciferase reporter cell lines were developed, EpRE(hNQO1)-LUX a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a66c955569a7a1d9dac8a000f68c8fe
http://resolver.tudelft.nl/uuid:a7d16055-5432-458e-8dc8-db7264681ea0
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6
A physiological threshold for protection against menadione toxicity by human NAD(P)H:quinone oxidoreductase (NQO1) in Chinese hamster ovary (CHO) cells
Autor: Ivonne M.C.M. Rietjens, Laura H.J. de Haan, Anne Marie J F Boerboom, Daniëlla van Capelle, Jac M.M.J.G. Aarts, Annemieke J M De Ruijter, Anil K. Jaiswal
Publikováno v: Biochemical Pharmacology 64 (2002)
Biochemical Pharmacology, 64, 1597-1603
NAD(P)H:quinone oxidoreductase 1 (NQO1) has often been suggested to be involved in cancer prevention by means of detoxification of electrophilic quinones. In the present study, a series of Chinese hamster ovary (CHO) cell lines expressing various ele
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4307a427e48f506f2bc45b1efe3a741
https://pubmed.ncbi.nlm.nih.gov/12429349
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