Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Anne-Marie Heegaard"'
Autor:
Tais Stangerup, Lise Mette Rahbek Gjerdrum, Michael Bzorek, Line Andersen, Anne-Marie Heegaard, Lars N. Jorgensen, Magnus S. Ågren
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3346 (2024)
Our objective was to investigate the effects of topically applied neuropeptide Y (NPY) on ischemic wounds. Initially, the animal model for ischemic wound healing was validated using 16 male Sprague Dawley albino rats. In the intervention study, an ad
Externí odkaz:
https://doaj.org/article/719364a3cdc74717972dc5be15a2aa06
Autor:
Rie B. Hansen, Manasi Sayilekshmy, Michala S. Sørensen, Astrid H. Jørgensen, Ida B. Kanneworff, Emma K. E. Bengtsson, Tomas A. Grum-Schwensen, Michael M. Petersen, Charlotte Ejersted, Thomas L. Andersen, Christina M. Andreasen, Anne-Marie Heegaard
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
BackgroundPain is a common complication for patients with metastatic bone disease. Animal models suggest that the pain, in part, is driven by pathological sprouting and reorganization of the nerve fibers innervating the bone. Here, we investigate how
Externí odkaz:
https://doaj.org/article/3daa2bba3d29446e90bd638e9c85eba0
Autor:
Muhammad Kassim Javaid, Alison Boyce, Natasha Appelman-Dijkstra, Juling Ong, Patrizia Defabianis, Amaka Offiah, Paul Arundel, Nick Shaw, Valter Dal Pos, Ann Underhil, Deanna Portero, Lisa Heral, Anne-Marie Heegaard, Laura Masi, Fergal Monsell, Robert Stanton, Pieter Durk Sander Dijkstra, Maria Luisa Brandi, Roland Chapurlat, Neveen Agnes Therese Hamdy, Michael Terrence Collins
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-17 (2019)
Abstract Fibrous Dysplasia / McCune Albright syndrome (FD/MAS) represents a wide spectrum of diseases due to somatic gain-of-function mutations of the GNAS gene. The mutation leads to overactivity in the target tissues and to a wide phenotype of clin
Externí odkaz:
https://doaj.org/article/bbcbbee103a0444987b518c3f8cf2459
Autor:
Marta Diaz‐delCastillo, Danna Kamstrup, Rikke Brix Olsen, Rie Bager Hansen, Thomas Pembridge, Brigita Simanskaite, Juan Miguel Jimenez‐Andrade, Michelle A Lawson, Anne‐Marie Heegaard
Publikováno v:
JBMR Plus, Vol 4, Iss 2, Pp n/a-n/a (2020)
ABSTRACT Bone pain is a serious and debilitating symptom of multiple myeloma (MM) that impairs the quality of life of patients. The underlying mechanisms of the pain are unknown and understudied, and there is a need for immunocompetent preclinical mo
Externí odkaz:
https://doaj.org/article/ee1179f5c8414121bb0c06b9c8892e8d
Autor:
Camilla Kristine Appel, Simone Gallego-Pedersen, Line Andersen, Sophie Blancheflor Kristensen, Ming Ding, Sarah Falk, Manasi Sayilekshmy, Charlotte Gabel-Jensen, Anne-Marie Heegaard
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Pain is a severe and debilitating complication of metastatic bone cancer. Current analgesics do not provide sufficient pain relief for all patients, creating a great need for new treatment options. The Src kinase, a non-receptor protein tyro
Externí odkaz:
https://doaj.org/article/8a2be61aace84981bb8033b783094820
Autor:
Xue Ying Zhang, Ahmed Barakat, Marta Diaz-delCastillo, Jan Vollert, Emily S. Sena, Anne-Marie Heegaard, Andrew S.C. Rice, Nadia Soliman
Publikováno v:
Zhang, X Y, Barakat, A, Diaz-delcastillo, M, Vollert, J, Sena, E S, Heegaard, A, Rice, A S C & Soliman, N 2022, ' A systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease associated persistent pain ', Pain, vol. Publish Ahead of Print . https://doi.org/10.1097/j.pain.0000000000002632
Zhang, X Y, Barakat, A, Diaz-delCastillo, M, Vollert, J, Sena, E S, Heegaard, A-M, Rice, A S C & Soliman, N 2022, ' Systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease-associated persistent pain ', Pain, vol. 163, no. 11, pp. 2076-2102 . https://doi.org/10.1097/j.pain.0000000000002632
Pain
Zhang, X Y, Barakat, A, Diaz-delCastillo, M, Vollert, J, Sena, E S, Heegaard, A-M, Rice, A S C & Soliman, N 2022, ' Systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease-associated persistent pain ', Pain, vol. 163, no. 11, pp. 2076-2102 . https://doi.org/10.1097/j.pain.0000000000002632
Pain
Burrowing behaviour is used to assess pain-associated behaviour in laboratory rodents. To gain insight into how models of disease-associated persistent pain and analgesics affect burrowing behaviour, we performed a systematic review and meta-analysis
Autor:
Michael S. Minett, Sarah Falk, Sonia Santana-Varela, Yury D. Bogdanov, Mohammed A. Nassar, Anne-Marie Heegaard, John N. Wood
Publikováno v:
Cell Reports, Vol 6, Iss 2, Pp 301-312 (2014)
Nav1.7, a peripheral neuron voltage-gated sodium channel, is essential for pain and olfaction in mice and humans. We examined the role of Nav1.7 as well as Nav1.3, Nav1.8, and Nav1.9 in different mouse models of chronic pain. Constriction-injury-depe
Externí odkaz:
https://doaj.org/article/7573c1aad53d411887931726ea7c84fb
Publikováno v:
Seminars in Cell & Developmental Biology. 112:49-58
Multiple myeloma is a bone marrow neoplasia with an incidence of 6/100,000/year in Europe. While the disease remains incurable, the development of novel treatments such as autologous stem cell transplantation, proteasome inhibitors and monoclonal ant
Autor:
Muhammad Kassim Javaid, Alison Boyce, Natasha Appelman-Dijkstra, Juling Ong, Patrizia Defabianis, Amaka Offiah, Paul Arundel, Nick Shaw, Valter Dal Pos, Ann Underhil, Deanna Portero, Lisa Heral, Anne-Marie Heegaard, Laura Masi, Fergal Monsell, Robert Stanton, Pieter Durk Sander Dijkstra, Maria Luisa Brandi, Roland Chapurlat, Neveen Agnes Therese Hamdy, Michael Terrence Collins
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-1 (2019)
The original version of this article [1] unfortunately included an error to an author’s name. Paul Arundel was inadvertently presented as Paul Arunde.
Externí odkaz:
https://doaj.org/article/03b8bed7003b41bc9e87d962f107425f
Autor:
John Thomas Helgstrand, Klaus Brasso, Martin Andreas Røder, Hein Vincent Stroomberg, Fie Juhl Vojdeman, Anne-Marie Heegaard, Christian M. Madsen, Anne Tjønneland, Anja Olsen, Henrik L. Jørgensen, Peter Schwarz, Bent Lind
Publikováno v:
Stroomberg, H V, Vojdeman, F J, Madsen, C M, Helgstrand, J T, Schwarz, P, Heegaard, A-M, Olsen, A, Tjønneland, A, Struer Lind, B, Brasso, K, Jørgensen, H L & Røder, M A 2021, ' Vitamin D levels and the risk of prostate cancer and prostate cancer mortality ', Acta Oncologica, vol. 60, no. 3, pp. 316-322 . https://doi.org/10.1080/0284186X.2020.1837391
BACKGROUND: Vitamin D has a role in bone turnover and potentially bone-metastatic spread of prostate cancer (PCa). The aim of this observational study was to address the association between levels of serum vitamin D, diagnosis of PCa and subsequent m