Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Anne-Marie Fortier"'
Autor:
Antoine A. Khalil, Daan Smits, Peter D. Haughton, Thijs Koorman, Karin A. Jansen, Mathijs P. Verhagen, Mirjam van der Net, Kitty van Zwieten, Lotte Enserink, Lisa Jansen, Abdelrahman G. El-Gammal, Daan Visser, Milena Pasolli, Max Tak, Denise Westland, Paul J. van Diest, Cathy B. Moelans, M. Guy Roukens, Sandra Tavares, Anne-Marie Fortier, Morag Park, Riccardo Fodde, Martijn Gloerich, Fried. J. T. Zwartkruis, Patrick WB. Derksen, Johan de Rooij
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Dense and aligned Collagen I fibers are associated with collective cancer invasion led by protrusive tumor cells, leader cells. In some breast tumors, a population of cancer cells (basal-like cells) maintain several epithelial characteristic
Externí odkaz:
https://doaj.org/article/50e49d8f27e74b6aa43d0874b11c6389
Autor:
Elena Kuzmin, Toby M. Baker, Tom Lesluyes, Jean Monlong, Kento T. Abe, Paula P. Coelho, Michael Schwartz, Joseph Del Corpo, Dongmei Zou, Genevieve Morin, Alain Pacis, Yang Yang, Constanza Martinez, Jarrett Barber, Hellen Kuasne, Rui Li, Mathieu Bourgey, Anne-Marie Fortier, Peter G. Davison, Atilla Omeroglu, Marie-Christine Guiot, Quaid Morris, Claudia L. Kleinman, Sidong Huang, Anne-Claude Gingras, Jiannis Ragoussis, Guillaume Bourque, Peter Van Loo, Morag Park
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113988- (2024)
Summary: The basal breast cancer subtype is enriched for triple-negative breast cancer (TNBC) and displays consistent large chromosomal deletions. Here, we characterize evolution and maintenance of chromosome 4p (chr4p) loss in basal breast cancer. A
Externí odkaz:
https://doaj.org/article/037f03f6925f4a5d977165ac992225f6
Publikováno v:
Insects, Vol 15, Iss 4, p 232 (2024)
Onion thrips (Thrips tabaci) can pose a significant threat to onion crops, causing leaf damage, reduced bulb size and quality, and yield loss during severe infestations. Conventional insecticide use has been the primary method for managing this pest
Externí odkaz:
https://doaj.org/article/38a3fb74669f4216a5b553c63b88002b
Autor:
Ipshita Nandi, Harvey W. Smith, Virginie Sanguin-Gendreau, Linjia Ji, Alain Pacis, Vasilios Papavasiliou, Dongmei Zuo, Stella Nam, Sherif S. Attalla, Sung Hoon Kim, Sierra Lusson, Hellen Kuasne, Anne-Marie Fortier, Paul Savage, Constanza Martinez Ramirez, Morag Park, John A. Katzenellenbogen, Benita S. Katzenellenbogen, William J. Muller
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Activation of the tyrosine kinase c-Src promotes breast cancer progression and poor outcomes, yet the underlying mechanisms are incompletely understood. Here, we have shown that deletion of c-Src in a genetically engineered model mimicking the lumina
Externí odkaz:
https://doaj.org/article/6febccb2e0664106aef4e61bab5617dd
Autor:
Qin Wu, Wail ba-alawi, Genevieve Deblois, Jennifer Cruickshank, Shili Duan, Evelyne Lima-Fernandes, Jillian Haight, Seyed Ali Madani Tonekaboni, Anne-Marie Fortier, Hellen Kuasne, Trevor D. McKee, Hassan Mahmoud, Michelle Kushida, Sarina Cameron, Nergiz Dogan-Artun, WenJun Chen, Yan Nie, Lan Xin Zhang, Ravi N. Vellanki, Stanley Zhou, Panagiotis Prinos, Bradly G. Wouters, Peter B. Dirks, Susan J. Done, Morag Park, David W. Cescon, Benjamin Haibe-Kains, Mathieu Lupien, Cheryl H. Arrowsmith
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Triple negative breast cancer is a deadly form of breast cancer with limited therapeutic options. Here the authors show the efficacy of GLUT1 pharmacological inhibition against a subset of tumors expressing RB1, thereby identifying RB1 protein level
Externí odkaz:
https://doaj.org/article/130018a3112a40a29ff505012c3352a4
Publikováno v:
Cancers, Vol 13, Iss 11, p 2605 (2021)
The molecular mechanism underlying the metabolic reprogramming associated with obesity and high blood cholesterol levels is poorly understood. We previously reported that cholesterol is an endogenous ligand of the estrogen-related receptor alpha (ERR
Externí odkaz:
https://doaj.org/article/6a0c0236b22e4cf9a0f655dd9b6c079c
Autor:
Hellen Kuasne, Anne-Marie fortier, Sandrine Busque, Simon Mathien, Paul Savage, Constanza Martinez Ramirez, Anie Monast, Margarita Soleinova, Atilla Omeroglu, Jamil Asselah, Nathaniel Bouganim, Sarkis Meterissian, Mark Basik, Morag Park
Publikováno v:
Cancer Research. 83:P3-08
Invasive breast carcinoma is a combination of heterogeneous diseases with distinct molecular and clinical features. Some subsets of breast cancer present major clinical challenges, including triple-negative, metastatic/recurrent disease and rare brea
Autor:
Anne-Marie Fortier
Publikováno v:
Citizenship Studies. 26:447-453
Autor:
Mathieu Lupien, Morag Park, Jason W. Locasale, Benjamin Haibe-Kains, Daniel D. De Carvalho, Cheryl H. Arrowsmith, David W. Cescon, Wail Ba-alawi, Hellen Kuasne, Alex Murison, Evelyne Lima-Fernandes, Paul Guilhamon, Xiaojing Liu, Alexandra N. Fedor, Paul Savage, Anne-Marie Fortier, Ilias Ettayebi, Felicia Tai, Yunchi Ingrid Kao, Constanza Martinez, Giacomo Grillo, Seyed Ali Madani Tonekaboni, Geneviève Deblois
Supplementary data, figures and table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1f2ce65ea88c56b786929d43f46294
https://doi.org/10.1158/2159-8290.22535243
https://doi.org/10.1158/2159-8290.22535243
Autor:
Mathieu Lupien, Morag Park, Jason W. Locasale, Benjamin Haibe-Kains, Daniel D. De Carvalho, Cheryl H. Arrowsmith, David W. Cescon, Wail Ba-alawi, Hellen Kuasne, Alex Murison, Evelyne Lima-Fernandes, Paul Guilhamon, Xiaojing Liu, Alexandra N. Fedor, Paul Savage, Anne-Marie Fortier, Ilias Ettayebi, Felicia Tai, Yunchi Ingrid Kao, Constanza Martinez, Giacomo Grillo, Seyed Ali Madani Tonekaboni, Geneviève Deblois
Tumor progression upon treatment arises from preexisting resistant cancer cells and/or adaptation of persister cancer cells committing to an expansion phase. Here, we show that evasion from viral mimicry response allows the growth of taxane-resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ade27e1b491d653c3d380a61e2922c1e
https://doi.org/10.1158/2159-8290.c.6547796.v1
https://doi.org/10.1158/2159-8290.c.6547796.v1