Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anne-Marie Carbonell"'
Autor:
Chibueze D. Nwagwu, Amanda V. Immidisetti, Michael Y. Jiang, Oluwasegun Adeagbo, David C. Adamson, Anne-Marie Carbonell
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 561 (2021)
Development of effective treatments for high-grade glioma (HGG) is hampered by (1) the blood–brain barrier (BBB), (2) an infiltrative growth pattern, (3) rapid development of therapeutic resistance, and, in many cases, (4) dose-limiting toxicity du
Externí odkaz:
https://doaj.org/article/8390e4ba2b9a4d398b7ff5386a53ec89
Clinically Explored Virus-Based Therapies for the Treatment of Recurrent High-Grade Glioma in Adults
Autor:
Amanda V. Immidisetti, Chibueze D. Nwagwu, David C. Adamson, Nitesh V. Patel, Anne-Marie Carbonell
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 138 (2021)
As new treatment modalities are being explored in neuro-oncology, viruses are emerging as a promising class of therapeutics. Virotherapy consists of the introduction of either wild-type or engineered viruses to the site of disease, where they exert a
Externí odkaz:
https://doaj.org/article/7da470daf326457782e6acbe48e9469b
Autor:
Chibueze D. Nwagwu, Amanda V. Immidisetti, Gabriela Bukanowska, Michael A. Vogelbaum, Anne-Marie Carbonell
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 40 (2020)
Introduction: OS2966 is a first-in-class, humanized and de-immunized monoclonal antibody which targets the adhesion receptor subunit, CD29/β1 integrin. CD29 expression is highly upregulated in glioblastoma and has been shown to drive tumor progressi
Externí odkaz:
https://doaj.org/article/e2d3dad5df424c85b592867ceed5d7ce
Autor:
Heather Ogana, Samantha Hurwitz, Zesheng Wan, Hye Na Kim, Samy Jambon, Hisham Abdel-Azim, Miller Huang, Moghimi Babak, Nora Heisterkamp, Anne-Marie Carbonell, Chintan Parekh, Marina Konopleva, Deepa Bhojwani, Yong-Mi Kim
Publikováno v:
Blood. 140:8799-8800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89602471a993cbd0b0ab410d5fc8614d
https://doi.org/10.1182/blood-2022-167902
https://doi.org/10.1182/blood-2022-167902
Publikováno v:
Neuro-Oncology. 24:vii82-vii83
BACKGROUND OS2966 is a first-in-class, humanized, and deimmunized anti-CD29 (β1integrin) monoclonal antibody. CD29 is a mechanosignaling receptor prominently upregulated in glioblastoma. Preclinical studies in mice and non-human primates have demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7aabcbb975ad0ff53597e402797d9c3
https://doi.org/10.1093/neuonc/noac209.313
https://doi.org/10.1093/neuonc/noac209.313
Autor:
Erwin Defensor, Anne-Marie Carbonell, W Shawn Carbonell, Danelle A Rolle-McFarland, Chibueze D. Nwagwu, Michael Y Jiang
Publikováno v:
Lab Animal. 49:227-232
Despite several therapeutics showing promise in nonclinical studies, survival from ovarian cancer remains poor. New technologies are urgently needed to optimize the translation of nonclinical studies into clinical successes. While most nonclinical se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a540656f0389944457c5f84ef564ddbc
https://doi.org/10.1038/s41684-020-0594-1
https://doi.org/10.1038/s41684-020-0594-1
Autor:
Chibueze D. Nwagwu, Gabriela Bukanowska, Amanda V. Immidisetti, Anne-Marie Carbonell, Michael A Vogelbaum
Publikováno v:
Pharmaceutics, Vol 13, Iss 40, p 40 (2021)
Pharmaceutics
Volume 13
Issue 1
Pharmaceutics
Volume 13
Issue 1
Introduction: OS2966 is a first-in-class, humanized and de-immunized monoclonal antibody which targets the adhesion receptor subunit, CD29/&beta
1 integrin. CD29 expression is highly upregulated in glioblastoma and has been shown to drive tumor
1 integrin. CD29 expression is highly upregulated in glioblastoma and has been shown to drive tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c672ea7561e7e49e0b0935c2f6748ab
https://www.mdpi.com/1999-4923/13/1/40
https://www.mdpi.com/1999-4923/13/1/40
Autor:
Amanda V. Immidisetti, Chibueze D. Nwagwu, Gabriela Bukanowska, Michael A. Vogelbaum, James K. Liu, Anne-Marie Carbonell
Publikováno v:
Neuro Oncol
BACKGROUND OS2966 is a first-in-class, humanized and deimmunized monoclonal antibody which antagonizes CD29/β1integrin, a mechanosignaling receptor prominently upregulated in glioblastoma. Preclinical studies in mice and non-human primates have demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7099c34c2ed0e42fb2636f9949dd903
https://europepmc.org/articles/PMC8598617/
https://europepmc.org/articles/PMC8598617/
Autor:
Anne-Marie Carbonell, Amanda V. Immidisetti, David Cory Adamson, Chibueze D. Nwagwu, Michael Y Jiang, Oluwasegun Adeagbo
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 561, p 561 (2021)
Pharmaceutics, Vol 13, Iss 561, p 561 (2021)
Development of effective treatments for high-grade glioma (HGG) is hampered by (1) the blood–brain barrier (BBB), (2) an infiltrative growth pattern, (3) rapid development of therapeutic resistance, and, in many cases, (4) dose-limiting toxicity du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18b65b7c568e743bdfa5c8a43b28534
Autor:
Nitesh V Patel, David Cory Adamson, Chibueze D. Nwagwu, Anne-Marie Carbonell, Amanda V. Immidisetti
As new treatment modalities are being explored in neuro-oncology, viruses are emerging as a promising class of therapeutics. Virotherapy consists of introduction of either wild-type or engineered viruses to the site of disease, where they exert anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a951e49f0cddf14ccc4bf46401451aa