Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Anne-Marie Aubertin"'
Autor:
Valérie Vivet-Boudou, Catherine Isel, Marwan Sleiman, Redmond Smyth, Nouha Ben Gaied, Patrick Barhoum, Géraldine Laumond, Guillaume Bec, Matthias Götte, Johnson Mak, Anne-Marie Aubertin, Alain Burger, Roland Marquet
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27456 (2011)
The occurrence of resistant viruses to any of the anti-HIV-1 compounds used in the current therapies against AIDS underlies the urge for the development of new drug targets and/or new drugs acting through novel mechanisms. While all anti-HIV-1 nucleo
Externí odkaz:
https://doaj.org/article/d26822192f44480dba292f5d7d2298a6
Publikováno v:
European journal of medicinal chemistry. 227
The synthesis and in vitro anti-HIV activity of a novel series of pronucleotides are reported. These prodrugs were characterized by a phosphorodithiolate structure, incorporating two O-pivaloyl-2-oxyethyl substituents as biolabile phosphate protectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1076350e70ede21837f9ca5d98dfa855
https://pubmed.ncbi.nlm.nih.gov/34695774
https://pubmed.ncbi.nlm.nih.gov/34695774
Publikováno v:
European journal of medicinal chemistry. 216
The synthesis and in vitro anti-HIV activity of a novel series of phosphoramidate pronucleotides including a S-pivaloyl-2-thioethyl (tBuSATE) group as biolabile phosphate protecting group are reported. Such constructs, obtained through different phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f006cde5152b9eedd26ee6133ed3e3
https://pubmed.ncbi.nlm.nih.gov/33711763
https://pubmed.ncbi.nlm.nih.gov/33711763
Autor:
Jean-Christophe Paillart, Géraldine Laumond, Roland Marquet, Alain Burger, Valérie Vivet-Boudou, Anne-Marie Aubertin, Yazan El Safadi
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (4), pp.1534-45. ⟨10.1021/jm901758f⟩
Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (4), pp.1534-45. ⟨10.1021/jm901758f⟩
International audience; With the goal of limiting HIV-1 proliferation by increasing the mutation rate of the viral genome, we synthesized a series of pyrimidine nucleoside analogues modified in position 5 of the aglycone moiety but unmodified on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0341f995368a6ce90fe924d53d64ddf2
https://doi.org/10.1021/jm901758f
https://doi.org/10.1021/jm901758f
Autor:
Maxime Mourer, Nicolas Psychogios, Geraldine Laumond, Jean-Bernard Regnouf-de-Vains, Anne-Marie Aubertin
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:36-45
Nine anionic water-soluble calix[4]arene species, incorporating sulfonate, carboxylate or phosphonate groups, six of them incorporating two 2,2′-bithiazole subunits in alternate position at the lower rim, have been synthesised and evaluated as anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc016e22f3097d3c3c04a2f79e2fe8dc
https://doi.org/10.1016/j.bmc.2009.11.016
https://doi.org/10.1016/j.bmc.2009.11.016
Autor:
Sonia Derdouch, Nicole Déglon, Francis Relouzat, Anne-Marie Aubertin, Stéphane Prost, Isabelle Dusanter-Fourt, Mikael Le Dantec, Sylvie Augé, Bernard Maillere, Gwenaelle Auregan, Marek Kirszenbaum, Roger Le Grand
Publikováno v:
médecine/sciences. 24:551-554
L’infection SIV induit la perte d’expression des facteurs de transcription Stat5a et Stat5b dans les cellules CD34+ Les patients infectes par le virus d’immunodeficience humaine (VIH) manifestent, en dehors des lymphopenies, de multiples defici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d58362cee4d4f455455dec8812568fc1
https://doi.org/10.1051/medsci/2008245551
https://doi.org/10.1051/medsci/2008245551
Autor:
J.-D. Abraham, A. Bohbot, Evelyne Schvoerer, Françoise Stoll-Keller, Marie Paule Kieny, Christine Thumann, Anne-Marie Aubertin
Publikováno v:
Gastroentérologie Clinique et Biologique. 32:59-68
Summary Aim Infection with hepatitis C virus (HCV) results in chronic hepatitis in more than 70% of cases. Alterations in the maturation of dendritic cells (DC) might play a role in the immune system's inability to eliminate the virus, although viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d6df59d3c459dff0de77dae624bf34
https://doi.org/10.1016/j.gcb.2007.12.006
https://doi.org/10.1016/j.gcb.2007.12.006
Autor:
Michel Evain, Ané Adjou, Sebastien Naud, François Huet, Anne-Marie Aubertin, Guillaume Viault, Muriel Pipelier, Didier Dubreuil, Stéphanie Legoupy
Publikováno v:
European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2007, pp.3296-3310
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2007, pp.3296. ⟨10.1002/ejoc.200700102⟩
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2007, pp.3296-3310
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2007, pp.3296. ⟨10.1002/ejoc.200700102⟩
The efficient synthesis of novel polyhydroxy-tetrahydropyrano-pyrroles from acetylenic carbohydrate precursors in three to four steps is described. The methodology involves, as key steps, the ring contraction of pyridazine intermediates obtained by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fa2e586f4e32deef9b0e02434628e5
https://doi.org/10.1002/ejoc.200700102
https://doi.org/10.1002/ejoc.200700102
Publikováno v:
Bioconjugate Chemistry. 17:1568-1581
In an approach to improve the pharmacological properties, safety and pharmacokinetic profiles, and their penetration into HIV reservoirs or sanctuaries, and consequently, the therapeutic potential of the current protease inhibitors (PIs) used in clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be805dbe333275d44a89a22909d8cfe6
https://doi.org/10.1021/bc060210m
https://doi.org/10.1021/bc060210m
Autor:
Gabriella Spiridon, Sophie Richert, Sandrine Einius-Haessig, Christiane Moog, Anne Marie Aubertin, Dominique Salmon-Ceron, Gianfranco Pancino, Renaud Burrer
Publikováno v:
AIDS Research and Human Retroviruses. 22:865-869
The aim of this study was to characterize the potent nonimmunoglobulin (Ig) inhibitory activity defected in plasma from some HIV-infected, efavirenz (EFV)-treated patients. Concentration of EFV in plasma was measured by HPLC and correlation with reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4407fec643b7da4fc248e5fb64866f4
https://doi.org/10.1089/aid.2006.22.865
https://doi.org/10.1089/aid.2006.22.865