Výsledky vyhledávání - "Anne-Lucie Nugues"

p65/RelA NF-κB fragments generated by RIPK3 activity regulate tumorigenicity, cell metabolism, and stemness characteristics

Autor: Yasmine Touil, Céline Latreche‐Carton, Hassiba El Bouazzati, Anne‐Lucie Nugues, Nathalie Jouy, Xavier Thuru, William Laine, Frederic Lepretre, Martin Figeac, Meryem Tardivel, Jérôme Kluza, Thierry Idziorek, Bruno Quesnel

Publikováno v: Journal of Cellular Biochemistry
Journal of Cellular Biochemistry, 2022, 123 (3), pp.543-556. ⟨10.1002/jcb.30198⟩

International audience; Receptor-interacting protein kinase 3 (RIPK3) can induce necroptosis, apoptosis, or cell proliferation and is silenced in several hematological malignancies. We previously reported that RIPK3 activity independent of its kinase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c9e57939f79f6861f8385d0b4db0a4
https://pubmed.ncbi.nlm.nih.gov/34927768

Zobrazit plný text záznamu

Identification of a novel synergistic induction of cell death by Smac mimetic and HDAC inhibitors in acute myeloid leukemia cells

Autor: Simone Fulda, Anne-Lucie Nugues, Sofie Steinwascher, Hannah Schoeneberger

Publikováno v: Cancer Letters. 366:32-43

Inhibitor of Apoptosis (IAP) proteins are expressed at high levels in acute myeloid leukemia (AML) and contribute to resistance to programmed cell death. Here, we report that inhibition of IAP proteins by the small-molecule Smac mimetic BV6 acts toge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b683e224c93f497e74b9fca788e25aa5
https://doi.org/10.1016/j.canlet.2015.05.020

Zobrazit plný text záznamu

Abstract 733: Modulating T cell immunity in tumors by targeting PD-L1 and neoantigens using a live attenuated oral Salmonella platform

Autor: Marc R. Mansour, Ming Wei, Heinz Lubenau, Sébastien Wieckowski, Lilli Podola, Philipp Beckhove, Amine Adda Berkane, Philippe Slos, Klaus M. Breiner, Anne-Lucie Nugues, Albrecht Meichle, Heiko Smetak

Publikováno v: Cancer Research. 78:733-733

Significant progresses have been achieved recently in cancer vaccines that aim at engaging or reengaging tumor directed T cells, in particular in the rapidly growing field of personalized immunotherapy. Yet novel immunization solutions to produce eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfa239300613df6a1c2b8f46ac0823e8
https://doi.org/10.1158/1538-7445.am2018-733

Zobrazit plný text záznamu

Live attenuated oral Salmonella platform for effective T- and B-cell targeting of PD-L1

Autor: Philippe Slos, Amine Adda Berkane, Marc R. Mansour, Anne-Lucie Nugues, Klaus M. Breiner, Albrecht Meichle, Philipp Beckhove, Ming Wei, Iris Kobl, Lilli Podola, Sébastien Wieckowski, Matthias Schroff, Heinz Lubenau, Heiko Smetak

Publikováno v: Journal of Clinical Oncology. 36:74-74

74 Background: Significant progresses have been recently achieved in cancer vaccines, yet novel immunization solutions to deliver efficiently tumor-associated antigens to professional antigen-presenting cells, and to overcome the peripheral tolerance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12b5d0013cda0114fc46236b94502556
https://doi.org/10.1200/jco.2018.36.5_suppl.74

Zobrazit plný text záznamu

Abstract B196: Live attenuated oral Salmonella platform for effective targeting of multiple tumor-associated epitopes and PD-L1

Autor: Matthias Schroff, Beckhove Philipp, Klaus M. Breiner, Lilli Podola, Heiko Smetak, Heinz Lubenau, Marc Mansour, Albrecht Meichle, Ming Wei, Sébastien Wieckowski, Anne-Lucie Nugues, Philippe Slos, Marco Springer, Iris Kobl, Amine Adda Berkane

Publikováno v: Molecular Cancer Therapeutics. 17:B196-B196

Significant progress has been achieved recently in cancer vaccines that aim at engaging or reengaging the tumor immunity, in particular in the rapidly growing field of personalized immunotherapy. Yet novel immunization solutions to deliver efficientl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a22320954cf592efbbb1278a2688b4f
https://doi.org/10.1158/1535-7163.targ-17-b196

Zobrazit plný text záznamu

Abstract 1342: RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage

Autor: Bruno Quesnel, Anne-Lucie Nugues, Anne Loyens, Céline Berthon, Dominique Hetuin, Thierry Idziorek, Elisabeth Bertrand, Hassiba Bouafia, Nathalie Jouy

Publikováno v: Cancer Research. 74:1342-1342

Introduction. Impairment in cell death pathways represents a general characteristic of most cancer cells. The receptor-interacting protein kinase 3 (RIP3) associates with RIP1 in a necrosome complex that can induce necroptosis, apoptosis, or cell pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51b2af259c2cf1e9e2d0e69ba129eb04
https://doi.org/10.1158/1538-7445.am2014-1342

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání