Variation and impact of polygenic hematologic traits in monogenic sickle cell disease

Autor: Thomas Pincez, Ken Sin Lo, Anne-Laure Pham Hung d’Alexandry d’Orengiani, Melanie E. Garrett, Carlo Brugnara, Allison E. Ashley-Koch, Marilyn J. Telen, Frederic Galacteros, Philippe Joly, Pablo Bartolucci, Guillaume Lettre

Publikováno v: Haematologica, Vol 108, Iss 3 (2022)

Several of the complications observed in sickle cell disease (SCD) are influenced by variation in hematologic traits (HT), such as fetal hemoglobin (HbF) level and neutrophil count. Previous large-scale genome-wide association studies carried out in

Externí odkaz: https://doaj.org/article/166842d6076144de914c1868e81d6859

Psychometric characteristics of the Revised Illness Perception Questionnaire (IPQ-R) in adults with sickle cell disease

Autor: Damien Oudin Doglioni, Anne-Laure Pham-Hung D’Alexandry D’Orengiani, Frédéric Galactéros, Marie-Claire Gay

Publikováno v: Health Psychology and Behavioral Medicine, Vol 10, Iss 1, Pp 60-80 (2022)
Health Psychology and Behavioral Medicine
article-version (VoR) Version of Record

Objective Sickle cell disease (SCD) is the most frequent monogenic disease worldwide. Psychological and behavioural factors are often reported as playing a significant role in predicting SCD health outcomes. When focusing on adaptation to a specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16423b8d6736bcd714b9a3ff72a36998
https://doaj.org/article/35287c86692e4120b21c8c0f8c147c26

Fetal Hemoglobin Induced Improvement in Relative Age of Sickle Red Blood Cells Determined through Glycated Hemoglobin Assessment By Flow Cytometry

Autor: Nassima Djouder, Nicolas Hebert, Stephane Moutereau, Emmanuel Adu, Steeve Lowenski, Anne-Laure Pham Hung D'Alexandry D'Orengiani, France Pirenne, Carlosse Keumeugni, Corinne Duguet, Pablo Bartolucci

Publikováno v: Blood. 140:8252-8253

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d68bd3c6d365500f211fba3dc041750c
https://doi.org/10.1182/blood-2022-165435

Cardiovascular phenotypes predict clinical outcomes in sickle cell disease: An echocardiography-based cluster analysis

Autor: Pablo Bartolucci, Frédéric Galactéros, Anne Laure Pham Hung d'Alexandry d'Orengiani, Geneviève Derumeaux, Simon Deswarte, François Lionnet, Marc Humbert, Christelle Chantalat, Gylna Loko, Laurent Savale, Bernard Maitre, Henri Guillet, Etienne Audureau, Jean-François Deux, Thomas d’Humières, Thibaud Damy, Jocelyn Inamo

Publikováno v: American journal of hematologyREFERENCES. 96(9)

Aims This study sought to link cardiac phenotypes in homozygous Sickle Cell Disease (SCD) patients with clinical profiles and outcomes using cluster analysis. Methods We analyzed data of 379 patients included in the French Etendard Cohort. A cluster

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8e3a288fade30db98d1a63ba200e47
https://pubmed.ncbi.nlm.nih.gov/34143511

Screening of FDA-Approved Drugs Using a MERS-CoV Clinical Isolate from South Korea Identifies Potential Therapeutic Options for COVID-19

Autor: Ji-Young Min, So Young Chang, David Shum, Magnar Bjørås, Wei Wang, Erlend Ravlo, Anne-Laure Pham Hung d’Alexandry d’Orengiani, Inhee Choi, Marc P. Windisch, Meehyun Ko, Aleksandr Ianevski, Denis E. Kainov, Soo Young Byun

Publikováno v: Viruses
Viruses, Vol 13, Iss 651, p 651 (2021)
Volume 13
Issue 4

Therapeutic options for coronaviruses remain limited. To address this unmet medical need, we screened 5406 compounds, including United States Food and Drug Administration (FDA)-approved drugs and bioactives, for activity against a South Korean Middle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63dd764df6b84d39a171b197c041e2ab
https://hdl.handle.net/11250/3045156