Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anne-Laure Lécrivain"'
Autor:
Laura Broglia, Anne-Laure Lécrivain, Thibaud T. Renault, Karin Hahnke, Rina Ahmed-Begrich, Anaïs Le Rhun, Emmanuelle Charpentier
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Bacterial RNA degradation is typically initiated by endoribonucleases and followed by exoribonucleases. Here the authors report the targetome of endoRNase Y in Streptococcus pyogenes, revealing the interplay between RNase Y and 3′-to-5′ exoribonu
Externí odkaz:
https://doaj.org/article/91cd2b74eef244269a407fef7ba055c4
Autor:
Rina Ahmed-Begrich, Emmanuelle Charpentier, Laura Broglia, Karin Hahnke, Thibaud T. Renault, Anne-Laure Lécrivain, Anaïs Le Rhun
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.1587. ⟨10.1038/s41467-020-15387-6⟩
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.1587. ⟨10.1038/s41467-020-15387-6⟩
RNA degradation is an essential process that allows bacteria to control gene expression and adapt to various environmental conditions. It is usually initiated by endoribonucleases (endoRNases), which produce intermediate fragments that are subsequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa42edda6571a525b034ba295bac50a8
https://hdl.handle.net/21.11116/0000-0006-8718-721.11116/0000-0006-871A-5
https://hdl.handle.net/21.11116/0000-0006-8718-721.11116/0000-0006-871A-5
Autor:
Emmanuelle Charpentier, Anaïs Le Rhun, Karin Hahnke, Rina Ahmed-Begrich, Anne-Laure Lécrivain, Thibaud T. Renault
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (46), pp.11814-11819. ⟨10.1073/pnas.1809663115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (46), pp.11814-11819. ⟨10.1073/pnas.1809663115⟩
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (46), pp.11814-11819. ⟨10.1073/pnas.1809663115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (46), pp.11814-11819. ⟨10.1073/pnas.1809663115⟩
mRNA decay plays an essential role in the control of gene expression in bacteria. Exoribonucleases (exoRNases), which trim transcripts starting from the 5′ or 3′ end, are particularly important to fully degrade unwanted transcripts and renew the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0862331e2e4e5c3eae0b2fc294c516f3
https://hdl.handle.net/21.11116/0000-0004-0158-821.11116/0000-0004-0156-A
https://hdl.handle.net/21.11116/0000-0004-0158-821.11116/0000-0004-0156-A
Autor:
Anne-Laure, Lécrivain, Anaïs, Le Rhun, Thibaud T, Renault, Rina, Ahmed-Begrich, Karin, Hahnke, Emmanuelle, Charpentier
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance To cope with harsh environments and cause infection, bacteria need to constantly adjust gene expression. Ribonucleases (RNases) control the abundance of regulatory and protein-coding RNA through degradation and maturation. The current ch
Autor:
Anne-Laure Lécrivain, Solange Lise Materne, Laura Broglia, Karin Hahnke, Emmanuelle Charpentier, Anaïs Le Rhun
Publikováno v:
RNA biology
RNA Biology
RNA Biology
Endoribonuclease Y (RNase Y) is a crucial regulator of virulence in Gram-positive bacteria. In the human pathogen Streptococcus pyogenes, RNase Y is required for the expression of the major secreted virulence factor streptococcal pyrogenic exotoxin B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0e27b6b88ce2f80aa93fdbb3c33061
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-154094
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-154094
Autor:
Laura Broglia, Johan Reimegård, Estelle Proux-Wéra, Anne-Laure Lécrivain, Anaïs Le Rhun, Cristina Della Beffa, Emmanuelle Charpentier
Publikováno v:
Nucleic Acids Research
A better understanding of transcriptional and post-transcriptional regulation of gene expression in bacteria relies on studying their transcriptome. RNA sequencing methods are used not only to assess RNA abundance but also the exact boundaries of pri
Autor:
Ines Fonfara, Kira S. Makarova, Janek Bzdrenga, Anaïs Le Rhun, Krzysztof Chylinski, Emmanuelle Charpentier, Eugene V. Koonin, Anne-Laure Lécrivain
Publikováno v:
Nucleic Acids Research
The CRISPR-Cas-derived RNA-guided Cas9 endonuclease is the key element of an emerging promising technology for genome engineering in a broad range of cells and organisms. The DNA-targeting mechanism of the type II CRISPR-Cas system involves maturatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c293a1cd87647fa5e24a73edd33c45
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-87653
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-87653