Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anne-Katrin Fabian"'
Autor:
Anne-Katrin Fabian, Andreas März, Sonja Neimanis, Ricardo M Biondi, Christian Kozany, Felix Hausch
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57508 (2013)
The FK506-binding protein 51 (FKBP51) is an Hsp90-associated co-chaperone which regulates steroid receptors and kinases. In pancreatic cancer cell lines, FKBP51 was shown to recruit the phosphatase PHLPP to facilitate dephosphorylation of the kinase
Externí odkaz:
https://doaj.org/article/6ced5f649c81470a8c0a399ccadf0b7e
Publikováno v:
Molecular and Cellular Biology. 33:1357-1367
The immunosuppressant and anticancer drug rapamycin works by inducing inhibitory protein complexes with the kinase mTOR, an important regulator of growth and proliferation. The obligatory accessory partner of rapamycin is believed to be FK506-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257bfb6d522d659a5adb514770eb0add
https://doi.org/10.1128/mcb.00678-12
https://doi.org/10.1128/mcb.00678-12
Publikováno v:
Journal of experimental botany. 56(412)
The medicinally applied tropane alkaloids hyoscyamine and scopolamine are produced in Atropa belladonna L. and in a small number of other Solanaceae. Calystegines are nortropane alkaloids that derive from a branching point in the tropane alkaloid bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bff6b3f83859ab0dd95a8f12e20099c
https://pubmed.ncbi.nlm.nih.gov/15642710
https://pubmed.ncbi.nlm.nih.gov/15642710
Autor:
Anne-Katrin, Fabian
Publikováno v:
Pflege Zeitschrift. 57(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::030ca1fa52344436a84423924621f52f
https://pubmed.ncbi.nlm.nih.gov/15497882
https://pubmed.ncbi.nlm.nih.gov/15497882
Autor:
Uwe Koch, Y. Wang, B. Hoogeland, R. Gopalakrishnan, Christian Kozany, Andreas Bracher, C. Kress, Anne-Katrin Fabian, Felix Hausch, Alexander Kirschner
The design of efficient ligands remains a key challenge in drug discovery. In the quest for lead-like ligands for the FK506-binding protein 51 (FKBP51), we designed two new classes of bicyclic sulfonamides to probe the contribution of conformational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ce218b4b2850e17135b2aa507a52ee
https://infoscience.epfl.ch/record/189077
https://infoscience.epfl.ch/record/189077
