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pro vyhledávání: '"Anne-Kathrin Knuth"'
Autor:
Anne-Kathrin Knuth, Stefanie Rösler, Barbara Schenk, Lisa Kowald, Sjoerd J.L. van Wijk, Simone Fulda
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 1, Pp 74-81 (2019)
Interferons (IFNs) are key players in the tumor immune response and act by inducing the expression of IFN-stimulated genes (ISGs). Here, we identify the mixed-lineage kinase domain-like pseudokinase (MLKL) as an ISG in various cancer cell lines. Both
Externí odkaz:
https://doaj.org/article/9bf0ec570bf74f28abe3cca90f4d20db
Autor:
Sjoerd J L van Wijk, Anne-Kathrin Knuth, Stefanie Rösler, Barbara Schenk, Lisa Kowald, Simone Fulda
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 1, Pp 74-81 (2019)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Interferons (IFNs) are key players in the tumor immune response and act by inducing the expression of IFN-stimulated genes (ISGs). Here, we identify the mixed-lineage kinase domain-like pseudokinase (MLKL) as an ISG in various cancer cell lines. Both
Smac mimetics and type II interferon synergistically induce necroptosis in various cancer cell lines
Autor:
Stefanie Roesler, Simone Fulda, Anne-Kathrin Knuth, Ines Eckhardt, Michael John Cekay, Tanja Frank
Publikováno v:
Cancer letters. 410
Since cancer cells often evade apoptosis, induction of necroptosis as another mode of programmed cell death is considered a promising therapeutic alternative. Here, we identify a novel synergistic interaction of Smac mimetics that antagonize x-linked