Zobrazeno 1 - 10
of 446
pro vyhledávání: '"Anne-Geneviève MARCELIN"'
Autor:
Aude Boulay, Emmanuel Quevarec, Isabelle Malet, Giuseppe Nicastro, Célia Chamontin, Suzon Perrin, Corinne Henriquet, Martine Pugnière, Valérie Courgnaud, Mickaël Blaise, Anne-Geneviève Marcelin, Ian A Taylor, Laurent Chaloin, Nathalie J Arhel
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 11, Pp 2918-2945 (2024)
Abstract HIV-1 capsids cross nuclear pore complexes (NPCs) by engaging with the nuclear import machinery. To identify compounds that inhibit HIV-1 nuclear import, we screened drugs in silico on a three-dimensional model of a CA hexamer bound by Trans
Externí odkaz:
https://doaj.org/article/7cbc18f74cf040398f77493b6d8d2daf
Autor:
Johannes C. Botha, Karen Zafilaza, Cathia Soulie, Nicolas Yin, Moira Spyer, Sofia Balaska, Stella Chatziioannidou, Vaia Tsiakalou, George Papadakis, Lemonia Skoura, Alexandros Zafiropoulos, George Sourvinos, Olivier Vandenberg, Anne-Geneviève Marcelin, Electra Gizeli, Eleni Nastouli
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 12 (2024)
ABSTRACT The goal of this study is to test a novel device and methodology based on the “Pebble” platform and real-time quantitative colorimetric loop-mediated isothermal amplification (qcLAMP) during SARS-CoV-2 detection using crude samples and e
Externí odkaz:
https://doaj.org/article/93f5ca41a7d04a938a193adae9065442
Comparison of the indirect immunofluorescence assay and a commercial ELISA to detect KSHV antibodies
Autor:
Valentin Leducq, Léa Ben Said, Sophie Sayon, Vincent Calvez, Anne-Geneviève Marcelin, Aude Jary
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic virus involved in several diseases. The gold standard for KSHV sero diagnosis remains the indirect immunofluorescence assay (IFA), which is time-consuming and operator-dependen
Externí odkaz:
https://doaj.org/article/e05f463c7aea472b8ea5e4b6c5c793b1
Autor:
Olivier Lambotte, Pierre Delobel, Jean-Philippe Spano, Kevin Bihan, Dominique Costagliola, Christine Katlama, Anne-Geneviève Marcelin, Laurent Greillier, Baptiste Abbar, Armelle Lavole, Séverine Gibowski, Cathia Soulié, Lambert Assoumou, Raghiatou Baldé, Thierry Allegre, Alain Makinson, Olivia Zaegel-Faucher, Marianne Veyri, Mathilde Bertheau, Michèle Algarte Genin, Marine Baron
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background Immune checkpoint inhibitors (ICIs) have been a major advance in cancer management. However, we still lack prospective real-world data regarding their usage in people with HIV infection (PWH).Methods The ANRS CO24 OncoVIHAC study (NCT03354
Externí odkaz:
https://doaj.org/article/69894f86f8e24e439ccac9ecea674593
Autor:
Garyfallia Poulakou, Pierre-Joseph Royer, Nikolay Evgeniev, Gwénaëlle Evanno, Françoise Shneiker, Anne-Geneviève Marcelin, Bernard Vanhove, Odile Duvaux, Stéphane Marot, Vincent Calvez
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionXAV-19 is a glyco-humanized swine polyclonal antibody targeting SARS-CoV-2 with high neutralizing activity. The safety and clinical efficacy of XAV-19 were investigated in patients with mild to moderate COVID-19.MethodsThis phase II/III,
Externí odkaz:
https://doaj.org/article/b72ce91525ff4694b55c65ba81e477f4
Autor:
Karen Zafilaza, Jonathan Bellet, Aurélie Truffot, Vincent Foulongne, Manuela Mireille Onambele, Maud Salmona, Camille Vellas, Claire Périllaud-Dubois, Audrey Mirand, Elisabeth André-Garnier, Enagnon Kazali Alidjinou, Ségolène Brichler, Honorine Fenaux, Magali Bouvier-Alias, Cédric Hartard, Céline Dorival, Fabrice Carrat, Anne-Geneviève Marcelin, Karl Stefic, Cathia Soulie
Publikováno v:
Viruses, Vol 16, Iss 10, p 1542 (2024)
Background: Neutralizing antibodies targeting the SARS-CoV-2 Spike protein reduce COVID-19-related risk of hospitalization, particularly in high-risk individuals. The COCOPREV-R study aimed to evaluate and compare clinical outcomes in high-risk SARS-
Externí odkaz:
https://doaj.org/article/11a29272a1314243b6d35f559956a600
Autor:
Sara Thietart, Antoine Rozes, Florence Tubach, Stéphane Marot, Anne-Geneviève Marcelin, Mathieu Raux, Hélène Vallet, Bruno Riou, Jacques Boddaert, Lorène Zerah
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Mortality is high in older patients hospitalized with COVID-19. Previous studies observed lower mortality during the Omicron wave, yet no data is available on older patients. The objective was to compare in-hospital mortality betw
Externí odkaz:
https://doaj.org/article/199b51eca44b49d3b1bc36009e0baf89
Autor:
Kathleen Gärtner, Sara Domínguez-Rodríguez, Judith Heaney, Triantafylia Gkouleli, Paul Grant, Karim Dorgham, Delphine Sauce, Cathia Soulie, Eloise J. Busby, Denise M. O’Sullivan, Moira Spyer, Johannes C. Botha, Maria Angeles Muñoz-Fernandez, Alfredo Tagarro, Nicola Cotugno, Jim F. Huggett, Nigel Klein, Paolo Palma, Pablo Rojo Conejo, Caroline Foster, Carlo Giaquinto, Paolo Rossi, Deborah Persaud, Anita De Rossi, Anne-Geneviève Marcelin, Eleni Nastouli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionInitiation of antiretroviral treatment (ART) in patients early after HIV-infection and long-term suppression leads to low or undetectable levels of HIV RNA and cell-associated (CA) HIV DNA and RNA. Both CA-DNA and CA-RNA, overestimate the
Externí odkaz:
https://doaj.org/article/4ff5de9e0e7d46feaef69aac5332bac4
Autor:
Gervillien Arnold Malonga, Almoustapha Issiaka Maiga, Dimitry Moudiongui Mboungou Malanda, Mahamadou Saliou, Juthèce Private Malanda-Kiminou, Oumar Dolo, Anicet Luc Magloire Boumba, Alhassane Ba, Robert Murphy, Jean Félix Peko, Anne-Geneviève Marcelin, Vincent Calvez, Stéphane Marot
Publikováno v:
Ticks and Tick-Borne Diseases, Vol 15, Iss 1, Pp 102276- (2024)
Crimean-Congo hemorrhagic fever virus (CCHFV) is the causative agent of Crimean-Congo hemorrhagic fever (CCHF), a highly contagious and potentially fatal emerging disease. We assessed CCHFV seroprevalence by conducting a serological survey of two coh
Externí odkaz:
https://doaj.org/article/4d4cfcae05d64864b34e66448c0e478c
Autor:
Nadine Tarantino, Elena Litvinova, Assia Samri, Cathia Soulié, Véronique Morin, Alice Rousseau, Karim Dorgham, Christophe Parizot, Olivia Bonduelle, Alexandra Beurton, Makoto Miyara, Pascale Ghillani, Julien Mayaux, Raphael Lhote, Jean-Marc Lacorte, Anne-Geneviève Marcelin, Zahir Amoura, Charles-Edouard Luyt, Guy Gorochov, Amélie Guihot, Vincent Vieillard
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionIncreasing evidence has shown that coronavirus disease 19 (COVID-19) severity is driven by a dysregulated immunological response. Previous studies have demonstrated that natural killer (NK) cell dysfunction underpins severe illness in COV
Externí odkaz:
https://doaj.org/article/d2455d1f075a4e8e82ac78227b02e211