Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anne-Gaëlle Bourdat"'
Autor:
Julian Garcia, Anne-Gaëlle Bourdat, Yoann Roupioz, Jean Lhomme, Christian Coulombeau, Eric Defrancq, Mitsuharu Kotera
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
On the basis of molecular modeling studies, the 7-nitroindole nucleoside 1 was selected as a suitable photochemical precursor for photochemical generation of the C1′ deoxyribosyl radical under irradiation, which led to 2′-deoxyribonolactone. The
Autor:
Anthony Romieu, Didier Gasparutto, Jean Cadet, Anne-Gaëlle Bourdat, Cédric d'Ham, Victor Duarte
Publikováno v:
Biochimie. 82:19-24
Modified oligodeoxyribonucleotides (ODNs) are powerful tools to assess the biological significance of oxidized lesions to DNA. For this purpose, we developed original synthetic pathways for the site-specific insertion of several oxidized bases into D
Publikováno v:
ChemInform. 30
Autor:
Eric Defrancq, Mitsuharu Kotera, Anne-Gaëlle Bourdat, Christian Coulombeau, Jean Lhomme, Julian Garcia, Muriel Jourdan
Publikováno v:
ChemInform. 30
A highly efficient synthetic method for incorporation of the deoxyribonolactone lesion into oligonucleotides was developed using the photochemical properties of 7-nitroindole.
Autor:
Jean Cadet, Anthony Romieu, Cédric d'Ham, Didier Gasparutto, Anne-Gaëlle Bourdat, Victor Duarte
Publikováno v:
ChemInform. 31
Modified oligodeoxyribonucleotides (ODNs) are powerful tools to assess the biological significance of oxidized lesions to DNA. For this purpose, we developed original synthetic pathways for the site-specific insertion of several oxidized bases into D
Autor:
Sophie Bellon, Sylvie Sauvaigo, Didier Gasparutto, Jean-Luc Ravanat, Sandrine Frelon, Evelyne Muller, Jean Cadet, Anne-Gaëlle Bourdat, M. Berger, Victor Duarte, Thierry Douki
Publikováno v:
Biological Chemistry
Biological Chemistry, De Gruyter, 2002, 383 (6), pp.933-943
Biological Chemistry, 2002, 383 (6), pp.933-943
Biological Chemistry, De Gruyter, 2002, 383 (6), pp.933-943
Biological Chemistry, 2002, 383 (6), pp.933-943
This review discusses recent aspects of oxidation reactions of DNA and model compounds involving mostly OH radicals, one-electron transfer process and singlet oxygen ( 1 O 2 ). Emphasis is placed on the formation of double DNA lesions involving a pur
Publikováno v:
Nucleic acids research. 27(4)
Several studies have shown that ionizing radiation generates a wide spectrum of lesions to DNA including base modifications, abasic sites, strand breaks, crosslinks and tandem base damage. One example of tandem base damage induced by @OH radical inX-
Autor:
Julian Garcia, Anne-Gaëlle Bourdat, Muriel Jourdan, Mitsuharu Kotera, Eric Defrancq, Jean Lhomme, Christian Coulombeau
Publikováno v:
Scopus-Elsevier
A highly efficient synthetic method for incorporation of the deoxyribonolactone lesion into oligonucleotides was developed using the photochemical properties of 7-nitroindole.
Publikováno v:
Nucleosides and Nucleotides. 18:1349-1350
Both N(2-deoxy-β-D-erythro-pentofuranosyl)-formylamine (dβF) and 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dGuo) were introduced in synthetic oligonucleotides at a vicinal position via the solid phase phosphoramidite method in order to investiga
Publikováno v:
Journal of the American Chemical Society. 120:11810-11811