Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anne-Claire Groo"'
Autor:
Florian Daressy, Line Séguy, Loëtitia Favre, Sophie Corvaisier, Cécile Apel, Anne-Claire Groo, Marc Litaudon, Vincent Dumontet, Aurélie Malzert-Fréon, Sandy Desrat, Fanny Roussi, Aude Robert, Joëlle Wiels
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113546- (2022)
The overexpression of antiapoptotic members (BCL-2, BCL-xL, MCL-1, etc.) of the BCL-2 family contributes to tumor development and resistance to chemotherapy or radiotherapy. Synthetic inhibitors targeting these proteins have been developed, and some
Externí odkaz:
https://doaj.org/article/42554ec0867d47a2bab1e7e9b84fdb89
Autor:
Line Séguy, Léna Guyon, Manon Maurel, Pascal Verdié, Audrey Davis, Sophie Corvaisier, Vincent Lisowski, Patrick Dallemagne, Anne-Claire Groo, Aurélie Malzert-Fréon
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1626 (2021)
Background and Purpose: The activation of 5-HT4 receptors with agonists has emerged as a valuable therapeutic strategy to treat Alzheimer’s disease (AD) by enhancing the nonamyloidogenic pathway. Here, the potential therapeutic effects of tegaserod
Externí odkaz:
https://doaj.org/article/f5c812927505494e8ce09c82a9ac8d7d
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1141 (2020)
Among advanced formulation strategies, nanoemulsions are considered useful drug-delivery systems allowing to improve the solubility and the bioavailability of lipophilic drugs. To select safe excipients for nanoemulsion formulation and to discard any
Externí odkaz:
https://doaj.org/article/7593cf9622284f28b7a9f44e2c7a8442
Autor:
Thomas Adnet, Anne-Claire Groo, Céline Picard, Audrey Davis, Sophie Corvaisier, Marc Since, Frédéric Bounoure, Christophe Rochais, Loïc Le Pluart, Patrick Dallemagne, Aurélie Malzert-Fréon
Publikováno v:
Pharmaceutics, Vol 12, Iss 3, p 251 (2020)
Direct nose-to-brain delivery has been raised as a non-invasive powerful strategy to deliver drugs to the brain bypassing the blood-brain barrier (BBB). This study aimed at preparing and characterizing an innovative composite formulation, associating
Externí odkaz:
https://doaj.org/article/fbb8e2487303402abfb8886053e0b2c5
Autor:
Aude Robert, Joëlle Wiels, Line Séguy, Fanny Roussi, Aurélie Malzert-Fréon, Cécile Apel, Sandy Desrat, Vincent Dumontet, Vincent Guérineau, Jérôme Bignon, Florian Daressy, Marc Litaudon, Anne-Claire Groo, Florian Malard, Ewen Lescop
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (11), pp.1789-1798. ⟨10.1002/cmdc.202100011⟩
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (11), pp.1789-1798. ⟨10.1002/cmdc.202100011⟩
International audience; Drimane sesquiterpenoid dialdehydes are natural compounds with antiproliferative properties. Nevertheless, their mode of action has not yet been discovered. In this publication, we have demonstrated that various drimanes are p
Publikováno v:
Drug discovery today. 27(6)
Given the continual increase in the number of patients and the lack of curative treatment, the development of new therapies to treat Alzheimer's disease (AD) is becoming ever more urgent. In this review, we summarize the most promising preclinical st
Publikováno v:
Molecular Pharmaceutics
Molecular Pharmaceutics, American Chemical Society, 2021, 18 (1), pp.44-64. ⟨10.1021/acs.molpharmaceut.0c00857⟩
Molecular Pharmaceutics, American Chemical Society, 2021, 18 (1), pp.44-64. ⟨10.1021/acs.molpharmaceut.0c00857⟩
Surface functionalization of lipid-based nanocarriers (LBNCs) with targeting ligands has attracted huge interest in the field of nanomedicines for their ability to overcome some physiological barriers and their potential to deliver an active molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf7989c9cb7a722c058e964f7cf9da5
https://hal.archives-ouvertes.fr/hal-03340157
https://hal.archives-ouvertes.fr/hal-03340157
Autor:
Didier Goux, R. Delépée, Thomas Freret, Melanie Coolzaet, Aurélie Malzert-Fréon, Hippolyte Paysant, Marc Since, Anne-Claire Groo, Laurent Poulain, Anne Sophie Voisin-Chiret, Emilie Brotin, Gerald Nee, Louis-Bastien Weiswald, Siham Hedir
Publikováno v:
International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2020, 587, pp.119655-. ⟨10.1016/j.ijpharm.2020.119655⟩
International Journal of Pharmaceutics, 2020, 587, pp.119655-. ⟨10.1016/j.ijpharm.2020.119655⟩
International Journal of Pharmaceutics, Elsevier, 2020, 587, pp.119655-. ⟨10.1016/j.ijpharm.2020.119655⟩
International Journal of Pharmaceutics, 2020, 587, pp.119655-. ⟨10.1016/j.ijpharm.2020.119655⟩
Background Pyridoclax is an original lead, recently identified as very promising in treatment of chemoresistant ovarian cancers. To correct the unfavorable intrinsic physico-chemical properties of this BCS II drug, a formulation strategy was implied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07001b96429a36c6f7b16bdfb12db521
https://hal.archives-ouvertes.fr/hal-03492393
https://hal.archives-ouvertes.fr/hal-03492393
Autor:
Maria Stefania Sinicropi, Line Séguy, Annaluisa Mariconda, Francesco Puoci, Carmela Saturnino, Pasquale Longo, Jessica Ceramella, Domenico Iacopetta, Marc Since, Aurélie Malzert-Fréon, Anne-Claire Groo, Fanny Leroy
Publikováno v:
Journal of Drug Delivery Science and Technology. 66:102907
The aim of the present study was the proposal of a strategy to permit the safe use of the powerful antitumor agent Cisplatin. Considering the possibility of reducing the oxidative stress responsible for the Cisplatin induced nephrotoxicity by using a
Publikováno v:
Nanomedicine
Nanomedicine, Future Medicine, 2019, 14 (13), pp.1647-1662. ⟨10.2217/nnm-2018-0337⟩
Nanomedicine, Future Medicine, 2019, 14 (13), pp.1647-1662. ⟨10.2217/nnm-2018-0337⟩
International audience; Aim: Over the last decade, antimicrobial peptides (AMPs) have emerged as a promising alternative for the treatment of various infections. The aim of this work is to explore the potential of lipid nanocapsules for the delivery